Clinical trials: Decompression, Surgical
Surgery, Pain
Postoperative Music for Orbital Decompression
The purpose of this study is to evaluate the effect of music to the postoperative pain and discomfort after orbital decompression.
- Conditions
- Surgery, Pain, Musth
- Trial name
- NCT04933201
- Testing
- Music, Routine perioperative treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Spinal Stenosis
Physical Therapy vs Surgical Decompression for Lumbar Spinal Stenosis
This is a randomized controlled multicenter trail comparing physical therapy to surgical decompression in patients with lumbar spinal stenosis.
- Trial name
- PTvsSD (NCT04552145)
- Testing
- surgery, Physiotherapy
- Where
- 3 sites in Norway
- Volunteers
- 232 people
- Sponsor
- Norwegian University of Science and Technology
Degenerative Lumbar Spinal Stenosis
Biportal Endoscopy Spine Surgery (BESS )Versus Unilateral Laminotomy Bilateral Decompression (ULBD ): RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic decompression and the unilateral approach bilateral decompression in spinal stenosis
- Trial name
- NCT03302507
- Testing
- BESS, ULBD
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Lumbar Spinal Stenosis
Clinical Outcome Study of Minimally Invasive Decompression for Lumbar Spinal Stenosis
The study is a prospective outcome study to evaluate the effectiveness and treatment outcomes of microendoscopic decompressive laminotomy (MEDL) with objective evaluation tools.
- Trial name
- MEDLLSS (NCT00737607)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Degenerative Spinal Arthritis, Cervical Myelopathy
Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion
This research study is being conducted to help improve the pre-operative, intra-operative, and post-operative course for patients and enhance recovery.
- Conditions
- Degenerative Spinal Arthritis, Cervical Myelopathy, Spinal Stenosis
- Trial name
- NCT04315090
- Sponsor
- Mayo Clinic
Avascular Necrosis of Bone
Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression
The purpose of this study is to determine if surgical angiogenesis performed in talar avascular necrosis by free microvascular bone grafts from the medial femoral condyle is a superior technique compared to core decompression and…
- Trial name
- TalarAVN (NCT02289976)
- Testing
- core decompression
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- BG Trauma Center Ludwigshafen
Spinal Stenosis Lumbar, Spondylolisthesis
Randomized Control Trial of Quadratus Lumborum Block for Lumbar Spine Decompression and Fusion Surgery
Lumbar spinal decompression and fusion is a commonly performed procedure fro neural impingement and back pain from a variety of pathologies.
- Conditions
- Spinal Stenosis Lumbar, Spondylolisthesis, Fusion of Spine, Lumbar Region, Degeneration Spine
- Trial name
- NCT04447950
- Testing
- Type 2/posterior Quadratus Lumborum block
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assuta Medical Center
Hip Necrosis, Hip Injuries
The Treatment of Initial Stage of Hip Osteonecrosis: the Core Decompression
This retrospective study evaluates 52 cases of avascular necrosis of femoral head (AVN) treated by core decompression, bone chips allograft, fibrin platelet rich-plasma (PRF) and concentrated autologous mesenchymal stromal cells…
- Trial name
- NEC15 (NCT04210440)
- Testing
- Core decompression procedure
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Dante Dallari, MD
Complex Regional Pain Syndrome I (CRPS I), Nerve Entrapment Syndrome
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria.
- Trial name
- CRPS-SURG (NCT07263256)
- Testing
- Lesion-Specific Surgical Correction, Median Nerve Decompression
- Where
- Czechia
- Volunteers
- 74 people
- Sponsor
- Jitka Fricova
Lumbar Spinal Stenosis, Spondylolisthesis
Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
The objective of the clinical investigation is to assess the proportion of lumbar spinal stenosis surgical treatment plans that change when an objective measurement of spinal stability is included and applied following a simple…
- Trial name
- SPSI (NCT03754972)
- Testing
- Sagittal plane shear index (SPSI)
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Medical Metrics Diagnostics, Inc
Exophthalmos, Orbitopathy, Graves
Deep Lateral Wall Partial Rim-Sparing Orbital Decompression for Treatment of Thyroid-Related Orbitopathy
The described technique of DLW-PRS decompression for TRO using SONOPET(R) appears to be safe and effective, reducing the complications associated with decompressing the orbital floor and medial wall.
- Conditions
- Exophthalmos, Orbitopathy, Graves, Surgery
- Trial name
- NCT04025034
- Testing
- Orbital decompression with ultrasonic bone removal
- Volunteers
- 35 people
- Sponsor
- Hospital Universitario 12 de Octubre
Tethered Cord Syndrome
Efficacy and Safety of Nerve Root Axial Decompression Surgery in The Treatment of Tethered Cord Syndrome
Background: Tethered cord syndrome (TCS) is a progressive clinical condition including a series of neurological dysfunctions and deformities attributable to abnormally increased tension on the spinal cord, which is lacking…
- Trial name
- NCT03262844
- Testing
- Conservative treatment, Capsule surgery
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Changzheng Hospital
Lumbar Spinal Stenosis, Spondylolisthesis
Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS), is a common disorder of narrowing of the spinal canal in the lower part of the back. This causes discomfort in the legs when standing or walking because of pressure on the spinal nerves.There are…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT01455805
- Testing
- Minuteman Fusion Implant, surgical decompression
- Where
- 4 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Spinal Simplicity LLC
Single Level Lumbar Decompression and Fusion Spine Surgery
Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA (multimodal analgesia) compared to usual analgsic care.
- Trial name
- NCT02202369
- Testing
- Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Cervical Degenerative Disc Disease, Cervical Stenosis
Minimally Invasive Posterior Decompression of the Cervical Spine
Degenerative stenosis of the cervical spinal canal may be caused by the compression of the posterior part of the dural sac and spinal cord by the hypertrophied ligamentum flavum and facet joints, by the compression of the…
- Conditions
- Cervical Degenerative Disc Disease, Cervical Stenosis, Posterior Spine Surgery
- Trial name
- NCT06995300
- Testing
- minimally invasive decompression via the posterior approach
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Lumbar Spinal Stenosis
MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
This is a multi-center, prospective, clinical study to assess the clinical application and outcomes of MILD® Interlaminar Decompression in patients with symptomatic lumbar spinal stenosis.
- Trial name
- MiDAS I (NCT00956631)
- Testing
- Interlaminar Decompression
- Where
- 13 sites in United States
- Volunteers
- 78 people
- Sponsor
- Vertos Medical, Inc.
Failed Back Surgery Syndrome, SCS
Spinal Cord Stimulation Versus Instrumentation for FBSS
Low back pain affects people of all ages and has become the leading cause of living with disability worldwide. Patients, suffering from persistent pain after spinal surgery in the absence of any clear spinal pathology are defined…
- Conditions
- Failed Back Surgery Syndrome, SCS, Neuromodulation, Spinal Cord Stimulation
- Trial name
- PROMISE (NCT05466110)
- Testing
- Spinal Cord Stimulation, Spinal Fusion Surgery
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- University Hospital Augsburg
Migraine
(Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist
To compare Botox-treated and Botox-untreated symptomatic tissues (defined as areas where the head hurts and the pain is felt) of chronic migraine (CM) patients using molecular studies.
- Trial name
- NCT03381261
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Massachusetts General Hospital