Clinical trials: Decompression, Surgical
Traumatic Brain Injury
Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients
This study was conducted in two parts: 1. This first part was designed to determine thiopentone dose requirement for induction of anaesthesia with and without the use of Bispectral Index monitoring - Participant and Care Provider…
- Trial name
- NCT03480880
- Testing
- Bispectral Index
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Spinal Fusion, Chronic Lower Back Pain
Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery
After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating…
- Trial name
- NCT06282770
- Testing
- Laser Diode Brace
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Cervical Spondylotic Myelopathy
Anterior Vs Posterior Procedures for Cervical Spondylotic Myelopathy: Prospective Randomized Clinical Trial
There is no difference in surgical outcomes for patients suffering from cervical spondylotic myelopathy treated with anterior decompression and fusion or posterior cervical laminoplasty.
- Trial name
- CSM (NCT00876603)
- Testing
- ACDF, Cervical laminoplasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Assessing Superion Clinical Endpoints vs. Decompression
PURPOSE: The primary purpose of this study is to demonstrate that the Composite Clinical Success of the study group receiving the Superion® IDS is not inferior to the success rate observed in the study group treated by direct…
- Trial name
- ASCEND (NCT03048955)
- Testing
- Superion® IDS, Direct decompression Surgery
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VertiFlex, Incorporated
Avascular Necrosis of Bone
Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression
The purpose of this study is to determine if surgical angiogenesis performed in talar avascular necrosis by free microvascular bone grafts from the femoral condyle is a superior technique compared to core decompression and…
- Trial name
- TalarAVN (NCT02291900)
- Testing
- core decompression
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- BG Trauma Center Ludwigshafen
Lumbar Stenosis, Familial
Sagittal Imbalance and Lumbar Stenosis Surgery: Decompression Without Implant
Lumbar stenosis (LSS) is the most frequent degenerative lumbar disease and is the most frequent indication for spinal surgery. When non-invasive treatments fail, decompression surgery is the gold standard therapy for the majority…
- Trial name
- CLE/EOS (NCT03065452)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Periampullary Cancer, Complications of Surgical Procedures or Medical Care
Comparison Between Fully Covered Metal Stents and Plastic Stents in Preoperative Biliary Drainage
This study is a prospective, randomized study to compare of outcome of fully covered metal stents with that of plastic stents for preoperative biliary drainage in distal common bile duct cancer, pancreas head cancer or ampullary…
- Conditions
- Periampullary Cancer, Complications of Surgical Procedures or Medical Care, Disorder of Bile Duct Stent
- Trial name
- NCT01789502
- Testing
- Fully covered metal stents, Plastic stents
- Where
- 3 sites in South Korea
- Volunteers
- 86 people
- Sponsor
- Inje University
Trigeminal Neuralgia, Tic Douloureux
Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict
The aim of the registry is a multicenter, prospective long-term data collection of patients suspected neurovascular conflict and referred for possible microvascular decompression (Jannetta procedure).
- Conditions
- Trigeminal Neuralgia, Tic Douloureux, Facial Pain, Glossopharyngeal Neuralgia
- Trial name
- PETER registry (NCT07135024)
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 5,001 people
- Sponsor
- Gerrit A Schubert
Lumbar Spinal Stenosis, Prehabilitation
Effectiveness of Prehabilitation for Patients Undergoing Lumbar Spinal Stenosis Surgery
Lumbar spinal stenosis (LSS) is a common spinal disease that leads to pain and disability. LSS is defined as lower extremity and perineal symptoms (e.g.
- Trial name
- NCT03388983
- Testing
- 6-week prehabilitation
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Migraine
(Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist
To compare Botox-treated and Botox-untreated symptomatic tissues (defined as areas where the head hurts and the pain is felt) of chronic migraine (CM) patients using molecular studies.
- Trial name
- NCT03381261
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Massachusetts General Hospital
Chronic Low Back Pain
A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
To administer the MSDR® (Musculoskeletal Disorder Reporting) instrument to document the musculoskeletal profile of patients with chronic low back pain, a prospective, non-randomized, multicenter treatment trial
- Trial name
- NCT00732394
- Testing
- MSDR
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedAppraise, Inc.
Failed Back Surgery Syndrome, Pain
Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome
The EVIDENCE trial is a randomized controlled trial comparing the therapeutic effectiveness and cost-effectiveness of the Precision® Spinal Cord Stimulation with that of reoperation as a treatment of pain in patients with Failed…
- Conditions
- Failed Back Surgery Syndrome, Pain, Back Pain
- Trial name
- Evidence (NCT01036529)
- Testing
- Precision Spinal Cord Stimulator, Back Surgery
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD.However, there have been no evidence of which degree of partial neuromuscular blockade should be performed or no…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Lateral Spread Response Monitoring
- Trial name
- NCT01598961
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB, No NMB
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center
Anterior Spinal Artery Compression Syndromes, Cervical Region
Effect of Placing the Endotracheal Tube Beyond Cervical C7 Level in Anterior Cervical Decompression and Fusion Surgery
Endotracheal intubation is performed to secure the patient's airway during general anaesthesia undergoing surgery. The procedure involves placing a tube known as endotracheal tube (ETT) mouth into the trachea.
- Trial name
- NCT06473077
- Testing
- ETT beyond C7 level
- Where
- Malaysia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Lumbar Spinal Stenosis, Surgery
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis
Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment.
- Trial name
- NCT04254757
- Testing
- Two different treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Pain, Postoperative, Spine Surgery
Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy
Effective non-opioid analgesics are of particular interest in ambulatory surgery, as providers may be able to reduce pain while avoiding perioperative opioids that can delay same day discharge.
- Trial name
- NCT04574778
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Rothman Institute Orthopaedics
Cervical Myelopathy, Cervical Radiculopathy
Investigation in Integrated Perspective of Radiculomyelopathy Patients
Cervical radiculopathy and myelopathy are common degenerative disorders, which can create a large amount of social and medical burden.
- Trial name
- NCT03396055
- Testing
- specific rehabilitation exercise
- Where
- Taiwan
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Low Back Pain, Cervical Pain
Prospective Study of Post Surgical Continued Spinal Pain Patients
Continued spinal pain following spine surgery is reported in up to 50% of patients. Disability and pain following spine surgery occurs.
- Conditions
- Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder
- Trial name
- NCT05401682
- Testing
- Cox chiropractic care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keiser University College of Chiropractic Medicine
LUMBAR STENOSIS
Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Stenosis of symptomatic lumbar canal is presented as a series of degenerative changes affecting the various vertebral segment structures, including: a joint zigoapofisária, yellow ligament, the articular capsule and the…
- Trial name
- Stenosis (NCT02879461)
- Testing
- LUMBAR DESCOMPRESSION
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Federal University of São Paulo