Clinical trials: Deconditioning
Immobility Syndrome, Deep Venous Thrombosis
Bedside Bike Early Mobilization Program for Inpatients
Hospital immobility leads to serious complications including muscle loss, weakness, delirium, pressure ulcers, and blood clots. Despite being medically stable, hospitalized patients spend over 90% of their time in bed due to…
- Conditions
- Immobility Syndrome, Deep Venous Thrombosis, Delirium, Hospital Acquired Condition
- Trial name
- BB-STEP (NCT07281638)
- Testing
- Bedside Bike
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Sedentary, Deconditioning
Eccentric Cycling : a Promising Training Modality for Sedentary People
The present study aims to compare the acute and training responses of (1) eccentric high intensity interval training (EI), (2)work-matched continuous eccentric training (EC), and (3) concentric high intensity interval training…
- Conditions
- Sedentary, Deconditioning, Eccentric Exercise Training, Eccentric Cycling Exercise
- Trial name
- NCT07189975
- Testing
- High intensity eccentric cycling training, Moderate intensity eccentric cycling training, High intensity concentric cycling training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Liege
Healthy
Deconditioning of Acquired Food Aversion
Background. Aversive conditioning impairs the rewarding value of a comfort meal. Our aim is to demonstrate the potential effect of deconditioning to reverse aversive conditioning and restore the hedonic postprandial response.
- Trial name
- NCT05897411
- Testing
- Unmasking previous conditioning procedure, No unmasking of previous conditioning
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Cardiovascular Deconditioning
Responses of the Cardiovascular Systems to Leg Exercises in Microgravity-like Conditions
One of the major issues in space explorations is the negative effect of prolonged exposure to very low gravity (i.e. a condition often referred to as microgravity or weightlessness) on astronauts' health.
- Trial name
- STAMAS (NCT02313142)
- Testing
- Leg exercises
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hospital-associated Deconditioning
Promoting Increased Physical Activity in Hospitalised Older Adults
The PIVOT study will explore the feasibility of training volunteers to deliver exercise to hospitalised older adults to improve the health of older people and prevent deconditioning while in hospital.
- Trial name
- PIVOT (NCT06017934)
- Testing
- Volunteer-led physical activity
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Rehabilitation, Post-Operative Condition
High-Intensity-Interval-Training in Geriatric Rehabilitation - A Feasibility Study
Study with Patients (40-60 participants) above the age of 65. There will be a comparison of regular training on ergometer (10 trainings within 2 weeks, 40 min each) to high intensity interval training on ergometer (6 trainings…
- Conditions
- Rehabilitation, Post-Operative Condition, Deconditioning After Acute Hospital, Oncology
- Trial name
- NCT04025385
- Testing
- High Intensity Interval Training
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Klinik Valens
Physical Deconditioning
Single Maximal Exercise Session and the Metabolic Response of Physically Inactive Young Adults (EASY-Study)
The goal of this clinical trial is to learn how the metabolic parameters of physically inactive young adults respond to a progressive exercise testing.
- Trial name
- EASY (NCT06680713)
- Testing
- Exercise
- Where
- Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sergio Martinez-Huenchullan
Weightlessness, Weightlessness; Adverse Effect
Thigh Cuffs to Prevent the Deconditioning Induced by 5 Days of Dry Immersion
The objective of the study is to investigate whether thigh cuffs help to prevent and/or reduce the deconditioning induced by 5 days of dry immersion and in particular the fluid shift and its related ophthalmological disorders.
- Trial name
- DI-Cuff (NCT03915457)
- Testing
- Dry immersion Control Group, Thigh cuffs intervention
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Cardiovascular Abnormalities, Weightlessness
Electroacupuncture is Effective in Cardiac Deconditioning Induced by Head-down Bed Rest
To investigate the changes of cardiovascular function during short-term simulated weightlessness after electroacupuncture (EA) treatment．
- Trial name
- NCT02300207
- Testing
- electronic acupuncture treatment instrument
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Dental Anxiety, Dental Phobia
Positive Psychological Deconditioning of Pediatric Patients With Dental Anxiety Through Artificial Intelligence
Pediatric patients who will be attending dental treatment at both the Orthodontics and Pediatric Dentistry Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences at the University of Pavia, Pavia, Italy and a…
- Trial name
- NCT06276478
- Testing
- AI-video, Verbal instructions
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Muscle Atrophy, Muscle Weakness
Evaluating Muscle Function After Ankle Surgery
Patients who are forced to rest or reduce activity as a result of illness, injury, or surgery often experience resulting muscle weakness.
- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Trial name
- NCT00060970
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Colon Cancer, Muscle Strengthening
Neuromuscular Deconditioning and Reconditioning in Colon Cancer Patients: an APA Muscle Rendorcement Program
Colon cancer is a real public health problem with more than 46,000 new cases diagnosed per year in France and about 650 cases in Burgundy.
- Trial name
- REMUSCLON (NCT05099211)
- Testing
- Muscle biopsies, Muscle Strengthening, Blood and urine samples
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Low Back Pain, Mechanical
Physical Deconditioning in COVID-19 Positive Patients and Non-Specific Low Back Pain
The purpose of this study is to take advantage of cohorts of patients followed for Coronavirus Disease 2019 (COVID19) expected to present poor physical fitness as the consequence of COVID19 to explore the relationship between…
- Trial name
- Phydel (NCT04990518)
- Where
- Switzerland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Atrophy, Muscular, Atrophy, Disuse
Blood Flow Restricted Electrical Stimulation During Immobilisation
Following injury or surgery to a limb, it is often immobilised to allow tissue healing. Short periods of disuse cause loss of muscle size and strength and impaired mechanical properties of tendons, which leads to reduced…
- Trial name
- NCT05093985
- Testing
- Neuromuscular electrical stimulation with blood flow restriction
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Weightlessness, Weightlessness; Adverse Effect
A New Nutritional Countermeasure to Prevent the Deconditioning Induced by 60 Days of Antiorthostatic Bed Rest
The objective of this study is to investigate whether the cocktail of natural antioxidants XXS-2A-BR2 comprising vitamin E and coupled with omega-3 helps to prevent and / or reduce the deleterious effects induced by long term…
- Trial name
- LTBRCocktail (NCT03594799)
- Testing
- Bed Rest Control Group, Cocktail intervention
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Haematological Cancer, Healthy
Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization
The goal of this clinical trial is to examine if pulsed electromagnetic fields (PEMF) can prevent or decrease physical deconditioning associated with prolonged hospitalisation and immobility of haematology patients.
- Trial name
- PEMF (NCT06744764)
- Testing
- PEMF (1mT), PEMF (0mT)
- Where
- 2 sites in Singapore
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Simulated Microgravity by Head Down Tilt Bedrest, Weightlessness
A 60 Days Head Down Tilt Bedrest With Artificial Gravity and Cycling Exercise on 24 Healthy Male (BRACE)
The objective of this study is to investigate whether a cycling exercise coupled with artificial gravity via a short-arm human centrifuge helps to prevent and / or reduce the deleterious effects induced by 60 days of…
- Trial name
- BRACE (NCT06544213)
- Testing
- Control Group, Countermeasure Supine Bike, Countermeasure AG-Bike
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Hot Weather; Adverse Effect, Immobilization, Tonic
Heat Therapy to Prevent Deconditioning During Immobilization
Animal models suggest that heat stress increases protein content and facilitates the recovery of atrophied muscle after an immobilization period, or following a chemically induced muscle injury in rats.
- Trial name
- NCT05021523
- Testing
- Hot ambient conditions exposures, Immobilization
- Where
- Qatar
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aspetar
PHYSICAL ACTIVITY
Relationship of Physical Condition and Functionality in Post-covid Patients
Cross-sectional, correlational cohort study where the variables Aerobic endurance (6-minute walk test), Muscle endurance (Medical research council MRC), Flexibility (Sit-and-reach test), Functionality (WHODAS 2.0), Number of days…
- Trial name
- NCT05422950
- Testing
- Relationship between physical condition and functionality in post-covid patients
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia