Clinical trials: Defibrillator
Sudden Cardiac Death, Heart Failure
Cardiac Rehab Retrospective Review (CR3)
All patients enrolled in the Austrian LifeVest Registry will be retrospectively screened for successfully completed ambulatory or stationary rehabilitation program.
- Conditions
- Sudden Cardiac Death, Heart Failure, Ventricular Arrythmia, Ventricular Tachycardia
- Trial name
- CR3 (NCT04675957)
- Testing
- cardiac rehabilitation
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Medical University of Graz
Ventricular Tachycardia
Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing
Cardiac arrest or sustained VT (ventricular tachycardia) in patients with heart disease is best treated with an ICD (implantable cardioverter defibrillator).
- Trial name
- NCT00585871
- Testing
- clonidine, metoprolol
- Where
- United States
- Sponsor
- James Martins
Myocarditis, Ventricular Arrythmia
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management
Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents.
- Conditions
- Myocarditis, Ventricular Arrythmia, Inflammatory Cardiomyopathy, Genetic Predisposition
- Trial name
- MYOCAR (NCT04521790)
- Testing
- support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Scientific Institute San Raffaele
Cardiomyopathies, Gender
Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy
The purpose of this registry is to prospectively assess outcomes of device-treated ventricular tachyarrhythmias and all-cause mortality in non-ischemic cardiomyopathy patients indicated for ICD or CRT-D implantation for the…
- Conditions
- Cardiomyopathies, Gender, Implantable Defibrillator User
- Trial name
- BIO-LIBRA (NCT03884608)
- Where
- 49 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Biotronik, Inc.
Respiration, Artificial
Feasibility of Ventilation Detection Via Standard Defibrillator Pads in Mechanically Ventilated Pediatric Patients
This study is a prospective, observational case series of a convenience sample of mechanically ventilated pediatric patients in the Pediatric ICU, Progressive Care Unit and Operating Room at the Children's Hospital of…
- Trial name
- Vent Detection (NCT00628875)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital of Philadelphia
Defibrillators, Implantable, Heart Failure, Congestive
Implantable Cardioverter Defibrillators And Magnetic Resonance Imaging of the Heart at 1.5 Tesla
To evaluate short-term and long-term effects by MR imaging on the technical and functional status of implantable cardioverter defibrillators.
- Trial name
- NCT00356239
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital, Bonn
The Patient Meets ACC/AHA/ESC Guidelines for Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronization Therapy (CRT-D) Device
Clinical Evaluation Of Remote Monitoring With Direct Alerts To Reduce Time From Event To Clinical Decision
St. Jude Medical developed the Merlin.net™ Patient Care Network (Merlin.net™ PCN) to augment or replace routine scheduled in-clinic visits.
- Trial name
- REACT (NCT01090349)
- Testing
- Implantation of an ICD/CRT-D device, Merlin.NET PCN
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 220 people
- Sponsor
- Abbott Medical Devices
Heart Failure, Myocardial Infarction
Prophylactic Substrate Ablation in Post-myocardial Patients Undergoing Defibrillator Implantation.
Prophylactic substrate ablation in post-MI patients undergoing defibrillator implantation reduces appropriate defibrillator therapies.
- Conditions
- Heart Failure, Myocardial Infarction, Ventricular Tachycardia
- Trial name
- NCT02780947
- Testing
- Ventricular tachycardia substrate ablation
- Volunteers
- 40 people
- Sponsor
- Spyridon Deftereos
Implantable Cardioverter Defibrillator (ICD), Aromatherapy
Implantable Cardioverter Defibrillator (ICD) Patients and Inhalation Aromatherapy
The effective management of anxiety and fatigue, which lead to negative physical, social, and psychological impacts and increase treatment costs in individuals with implanted cardioverter-defibrillators (ICD), is of great…
- Conditions
- Implantable Cardioverter Defibrillator (ICD), Aromatherapy, Anxiety, Fatigue Symptom
- Trial name
- ICD (NCT06874777)
- Testing
- Aromatherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- TC Erciyes University
Arrhythmia, Cardiac
Surface Electrocardiogram (ECG) Signal Recording for Implantable Subcutaneous String Defibrillator (ISSD) Development
Record cutaneous Electrocardiogram (ECG) data from positions corresponding to the expected subcutaneous locations of the Implantable Subcutaneous String Defibrillator (ISSD) using existing, approved ECG recording devices.
- Trial name
- NCT02991716
- Testing
- recorded patients
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NewPace Ltd
Sudden Cardiac Death
The International SubcutaneouS Implantable Cardioverter Defibrillator Registry (iSuSI)
The entirely subcutaneous implantable defibrillator (S-ICD) (Emblem, Boston Scientific, Marlborough, MA, USA) was introduced as a new therapeutic alternative to the conventional transvenous ICD in 2009 and implantations are…
- Trial name
- iSuSI (NCT05390047)
- Where
- Germany
- Volunteers
- 4,000 people
- Sponsor
- University of Luebeck
Cardiac Pacing, Electric Countershock
Follow-up of Patients With Implantable Cardioverter Defibrillators by Home Monitoring (ANVITE)
Patients with implantable cardioverter defibrillators (ICDs) should undergo regular device follow-ups every 3 months, to verify proper ICD function.
- Conditions
- Cardiac Pacing, Electric Countershock, Ventricular Tachyarrhythmia
- Trial name
- ANVITE (NCT00858559)
- Testing
- Implantable cardioverter defibrillator with Home Monitoring function, Standard implantable cardioverter defibrillator
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Tachycardia
PVC Response ''Atrial Pace'' Inducing Atrial Tachycardias
Premature ventricular contractions (PVC) are common phenomenon and occasionally retrograde conduction from ventricle to atrium occurs and may cause pacemaker mediated tachycardia.
- Trial name
- NCT05344456
- Testing
- Change in the device PVC algorithm to ''Off''
- Where
- Finland
- Volunteers
- 16 people
- Sponsor
- Helsinki University Central Hospital
Ventricular Tachycardia, Monomorphic
Fast VT Episodes Are Terminated by ATP One Shot
Many arrhythmias detected in the ventricular fibrillation (VF)-zone picture monomorphic ventricular tachycardia (VT) and, hence, could be terminated by antitachycardia pacing (ATP) treatment.
- Trial name
- FavoriteATP (NCT00617578)
- Testing
- ATP One Shot ON, ATP One Shot OFF
- Where
- 14 sites in Austria, Finland and 2 more
- Volunteers
- 194 people
- Sponsor
- Biotronik SE & Co. KG
Ventricular Fibrillation, Ventricular Tachycardia
Influence of Home Monitoring on the Clinical Status of Heart Failure Patients With an Impaired Left Ventricular Function
Re-hospitalizations or deaths by worsening heart failure are often preceded by distinct trends of clinical parameters such as atrial or ventricular arrhythmia, activity, heart rate variability, or ventricular ectopy.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Congestive Heart Failure
- Trial name
- IN-TIME (NCT00538356)
- Testing
- ICD or CRT-D with Home Monitoring feature deactivated, ICD or CRT-D with Home Monitoring feature activated
- Where
- 39 sites in Australia, Austria and 5 more
- Volunteers
- 720 people
- Sponsor
- Biotronik SE & Co. KG
Congestive Heart Failure, Sudden Cardiac Death
Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms
The purpose of this study is to determine whether waveforms of the intracardiac electrograms, acquired through an ICD, can be used: to predict malignant ventricular arrhythmias, requiring appropriate ICD therapies, and to predict…
- Conditions
- Congestive Heart Failure, Sudden Cardiac Death, Arrhythmia, Cardiomyopathies
- Trial name
- ICD-EGMs (NCT00916435)
- Where
- 2 sites in United States
- Volunteers
- 630 people
- Sponsor
- Johns Hopkins University
Arrhythmia, Bradycardia
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival…
- Conditions
- Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
- Trial name
- PPR (NCT00271180)
- Testing
- Device
- Where
- 333 sites in United States, Australia and 33 more
- Volunteers
- 20,000 people
- Sponsor
- Medtronic
MRI Scans, Magnetic Resonance Imaging
Registry of Patients for MRI With Non-MRI Conditional Pacemakers and ICD Non-MRI Conditional Pacemakers and ICD
The purpose of the registry is to accumulate pre-and post-scan device interrogation data for the purpose of determining the risk of MRI for patients with implantable devices.
- Conditions
- MRI Scans, Magnetic Resonance Imaging, Pacemaker, Implantable Cardioverter Defibrillator
- Trial name
- NCT02318550
- Testing
- MRI Scan
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Lancaster General Hospital
Hypertrophic Cardiomyopathy
Optimisation of Decision Making for Defibrillator Implantation in Hypertrophic Cardiomyopathy
The main objective of the study is to improve implantable cardioverter defibrillator (ICD) implantation decision-making processing relevance by developing a new prediction model of sudden cardiac death (SCD) in hypertrophic…
- Trial name
- OPTIM-HCM (NCT03846297)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree
Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic Devices
Objective: This clinical study employs a prospective, paired, self-controlled, non-inferiority, multicenter research design to assess the safety and efficacy of utilizing 5G cloud follow-up for CIED in parameters monitoring and…
- Conditions
- Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree, Heart Failure
- Trial name
- CIED-CARE (NCT06652750)
- Testing
- Routine Management, 5G Cloud Follow-up
- Where
- 2 sites in China
- Volunteers
- 688 people
- Sponsor
- The Third People's Hospital of Chengdu