Clinical trials: Deficiency Vitamins
Vitamin D Inadequacy, Vitamin D Deficiency
Clinical Approaches to Correcting Vitamin D Inadequacy and Maintaining Adequacy
Vitamin D is available in two forms, vitamin D2 and vitamin D3. It has previously been assumed that these two forms maintain blood vitamin D equally. However, this may not be the case.
- Trial name
- D2/D3 (NCT00692120)
- Testing
- Cholecalciferol (vitamin D3), Ergocalciferol (vitamin D2)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin d Deficiency
Peripheral Immunological Effects of High-dose Vitamin D Treatment in Healthy Subjects
Vitamin D deficiency is associated with the risk of developing MS. Vitamin D treatment has therefore been tested as a background treatment for this pathology, with a seemingly modest clinical effect.
- Trial name
- VDSS (NCT05654818)
- Testing
- Vitamin D
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cardiovascular Diseases, Vitamin D Deficiency
The Effect of Vitamin D Statues on Endothelial Function
In the United States, cardiovascular disease causes over one-third of all deaths and vitamin D deficiency is an epidemic. An increasing body of data suggests that low vitamin D status adversely impacts the cardiovascular system.
- Trial name
- CVD Cookie (NCT01049048)
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin D Deficiency, Vitamin; Excess Vitamin D (Nutritional)
Vitamin D Supplements on Markers for Cardiovascular Disease and Diabetes: an Individual Participant Data Meta-analysis
This meta-analysis will be conducted to study the effect on vitamin D supplements on markers for cardiovascular disease and diabetes using individual participant data from 12 RCTs.
- Trial name
- NCT02551835
- Volunteers
- 2,945 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Vitamin D Deficiency
The 'Hidden' Biological Impact of Vitamin D Deficiency: a Biomarker Study; Part 2
The investigators major aims are to: determine the vitamin D status of a group of young, apparently healthy adults in Hong Kong; examine inter-relationships between vitamin D status and biomarkers of DNA damage and repair…
- Trial name
- NCT02451787
- Testing
- Vitamin D
- Where
- Hong Kong
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Vitamin D Deficiency, Hypocalcemia
Effect of Vitamin D Supplement on Disease Activity in SLE
To study the effect of vitamin D supplementation on disease activity of SLE ( SLEDAI-2K ) and IL-6 level
- Conditions
- Vitamin D Deficiency, Hypocalcemia, Hyperparathyroidism, Systemic Lupus Erythematosus (Disorder)
- Trial name
- NCT05260255
- Testing
- vitamin D2 ( calciferol )
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Healthy
Study Comparing Two Isoforms of Vitamin D Supplements for Infants
There are two different types of vitamin D - vitamin D3 (animal source) and vitamin D2 (plant source). Almost all the usual vitamin D preparations for infants available in Canadian pharmacies contain vitamin D3 which may not be…
- Trial name
- NCT01190137
- Testing
- Cholecalciferol (D3) or ergocalciferol (D2)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- McGill University
Cytokine Storm
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
The effect of Weekly 50,000 IU vitamin D3 supplements on the serum levels of selected cytokines involved in cytokine storm of Covid-19; A randomized clinical trial in the Covid-19 uninfected people with vitamin D deficiency.
- Trial name
- NCT04476745
- Testing
- Vitamin D3
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Hypercholesterolemia, Cognitive Dysfunction
The Dual Impact of Homocysteine and Cholesterol on Cognitive Functions
The study evaluates if the relationship between total serum cholesterol is dependent on the total serum homocysteine. Fasting blood samples will taken from participants and two batteries of cognitive scales will be used to asses…
- Conditions
- Hypercholesterolemia, Cognitive Dysfunction, Hyperhomocysteinemia
- Trial name
- NCT03631238
- Testing
- Blood sampling for total cholesterol and homocysteine and cognitive assessment by psychometric tests.
- Where
- Egypt
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitamin D Deficiency
Comparison of 25-hydroxy Vitamin D Level in Caucasian Women Receiving Vitamin D Supplementation and Not Receiving Supplementation: a Randomized Controlled Trial.
The objective of this study is to assess whether vitamin D supplements are sufficient to increase females who are deficient or borderline deficient in vitamin D levels to normal levels.
- Trial name
- NCT00882505
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Vitamin D Deficiency, Pregnancy
Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome
The VitDTracking study focuses on the relevance of maternal vitamin D levels and their association with prematurity, aiming to improve maternal and child health outcomes, particularly by reducing avoidable preterm births.
- Trial name
- VitDTracking (NCT06292195)
- Testing
- Exposure
- Where
- 3 sites in Portugal
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Évora
Vitamin A Deficiency in Children
Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical Outcomes
Aim of the work is to assess the prevalence of vitamin A deficiency in critically ill children with sepsis and the association between vitamin A deficiency and clinical outcomes
- Trial name
- NCT06391437
- Testing
- Extraction of blood sample
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Benha University
Endothelial Dysfunction, Hyperhomocysteinemia
Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
The present study aims at investigating the effects of the oral supplementation with creatine on the systemic microvascular reactivity and plasma levels of homocysteine in vegetarian individuals of the vegan type.
- Trial name
- NCT02961972
- Testing
- monohydrate and micronized creatine
- Where
- Brazil
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Vitamin D Deficiency
The Genetic Effects on Vitamin D Supplementation
Vitamin D is essential for skeletal growth and bone health, deficiency causes rickets and osteomalacia. In the UK 29% of adults have vitamin D deficiency. It is recommended all adults take 10µg vitamin D supplement daily.
- Trial name
- NCT05802433
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Vitamin B6 Deficiency
Vitamin B6 Dependence of One-Carbon Metabolism
Marginal vitamin B6 deficiency, which occurs commonly worldwide, leads to a cellular deficiency of the coenzyme pyridoxal phosphate (PLP).
- Trial name
- NCT00877812
- Testing
- Arm 1 glycine and leucine, Arm 2 Intervention of Serine and methionine infusion
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Vitamin D Deficiency
Effect of Vitamin D Treatment on Fatigue
Primary objective -Change in Fatigue Assesment Score (FAS) between the first visit (baseline) and 28 (+maximum 7) days after oral administration of 100 000 E vitamin D (Cholecalciferol).
- Trial name
- NCT02022475
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Overweight, Hypovitaminosis D
Effects of Vitamin D Supplementation on Obesity, Inflammatory and Metabolic Markers
46 eligible overweight women with hypovitaminosis D are assigned to either vitamin D or control group using block randomization method.
- Trial name
- NCT05376865
- Testing
- Vitamin D supplement
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani, Ph.D.
Prediabetes, Vitamin D Deficiency
Effect of Vitamin D Deficiency and Vitamin D Supplementation on Glucose Metabolism
This study was intended to evaluate the effect of vitamin D supplementation on insulin sensitivity and pancreatic islet beta-cell function.
- Trial name
- NCT00749918
- Testing
- Cholecalciferol (vitamin D3)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Infertility, Female, Infertility
Vitamin D and Polycystic Ovarian Syndrome (PCOS)
Primary Objectives: To evaluate the efficacy of metformin and Vitamin D supplementation on serum insulin and serum androgen levels (Total testosterone, Steroid Hormone Binding Globulin, Free Androgen Index) levels compared…
- Conditions
- Infertility, Female, Infertility, Vitamin D Deficiency
- Trial name
- NCT03989778
- Testing
- Vitamin D
- Where
- 2 sites in Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Diarrhoea
Causes of Rotavirus Vaccine Failure in Zambian Children
Zambia recently introduced routine infant immunization against rotavirus - the most important cause of severe gastroenteritis and diarrhoea mortality in children.
- Trial name
- NCT01886833
- Where
- Zambia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia