Clinical trials: Deficits, Neurologic
Parkinson's Disease
Cognitive Rehabilitation in Parkinson's Disease
We are testing a computer game-style rehabilitation program for people with Parkinson's disease (PD). People with PD often have difficulty with motor planning, such as initiating or starting movements.
- Trial name
- NCT01085968
- Testing
- PC based training
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Bariatric Surgery, Gastric Motor Dysfunction
EGG Test as a Predictor for an Individual Response to Treatment by Various Bariatric Procedures
Total body weight loss (TBWL) after bariatric endoscopy (BE) is variable. Gastric emptying may be normal, rapid or delayed in patients with obesity and be a factor in variable BE outcomes.
- Conditions
- Bariatric Surgery, Gastric Motor Dysfunction, Gastroparesis
- Trial name
- NCT05731531
- Testing
- ELECTROGASTROGRAPHY
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Neurodevelopmental Disorders, Autism Spectrum Disorder
A Game-based Neurodevelopmental Assessment for Young Children
The aim of this study is to evaluate a novel tablet game-based neurodevelopmental assessment tool for young children aged 3 to 8 years old.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Dyslexia
- Trial name
- BRIGHTEN (NCT05780853)
- Testing
- Tablet Game-based Assessment - YARN assessment service, Adaptive Behavior Assessment System, Third Edition (ABAS-3), Demographic questionnaire
- Where
- United Kingdom
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Brightlobe Limited
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Epilepsy
Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery
This project will test the accuracy of a novel diffusion-weighted magnetic resonance imaging (DWMRI) approach using a deep convolutional neural network (DCNN) to predict an optimal resection margin for pediatric epilepsy surgery…
- Trial name
- NCT04986683
- Testing
- Brain magnetic resonance imaging, Neuro-psychology testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
ADHD
The Effects of Yoga on Attention, Impulsivity and Hyperactivity in Pre-school Age Children
This pilot project will evaluate yoga as an intervention to improve attention and reduce challenging behaviors such as hyperactivity and impulsivity, rated by parent and teachers, in preschool age children with or "at risk" for…
- Trial name
- NCT02642666
- Testing
- Children's Yoga
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Cognitive Deficits, Mild
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination
This randomized, double-blind, placebo-controlled trial will evaluate whether 12 weeks of supplementation with the probiotic Lactobacillus rhamnosus GG combined with colon-delivered riboflavin will improve cognitive performance…
- Trial name
- MENTOR (NCT07410052)
- Testing
- Experimental 1, Experimental 2
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Healthy, Shoulder Impingement Syndrome
Injury Prevention Programs in Overhead Athletes
To evaluate and describe the effect of performing an integrated injury prevention exercises on the variables considered as injury risk factors in overhead athletes
- Conditions
- Healthy, Shoulder Impingement Syndrome, Shoulder Injury, Shoulder Pain Chronic
- Trial name
- IPOverhead (NCT06747702)
- Testing
- Injury prevention workout
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Weight Loss, Muscle Loss
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance.
- Conditions
- Weight Loss, Muscle Loss, Bone Loss
- Trial name
- NCT01292395
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Stroke, Deficit in Manual Activities
Improving Bi-manual Activities in Stroke Patients With Application of Neuro-stimulation
Noninvasive brain stimulations (NIBS) will be used in healthy volunteers and in chronic stroke patients to improve bimanual activities and motor learning.
- Trial name
- NCT02308852
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication.
- Trial name
- DoDNAC (NCT04481048)
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Ischemic Stroke
The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment.
- Trial name
- NCT03702452
- Testing
- functional rehabilitation nursing program, control group
- Where
- China
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neurological Disorders, Health Adult Subjects
A Multicenter Interventional Study on the Use of a 3-Degree-of-Freedom (3DOF) Platform to Evaluate the Safety and Usability of the System and Its Impact on Balance, Proprioception, and Neurological Deficits in the Rehabilitation of Patients With Neurological Disorders.
This multicenter interventional study aims to evaluate a three-degrees-of-freedom dynamic platform (3DoF Platform) designed to support rehabilitation of balance, proprioception, and motor and cognitive functions in patients with…
- Trial name
- 3DOF (NCT07502937)
- Testing
- 3DOF balance board robotic platform group, Conventional Rehabilitation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Neurodevelopmental Disorders, Autism
Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies
The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year…
- Conditions
- Neurodevelopmental Disorders, Autism, ADHD, Intellectual Disability
- Trial name
- NCT06199362
- Where
- Sweden
- Volunteers
- 2,400,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Whiplash Injury of Cervical Spine, Muscle Weakness
Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders
The aim of this prospective observational study is to investigate whether the presence or absence of directional preference impacts movement coordination impairments as measured in patients with Whiplash Associated Disorders…
- Trial name
- NCT06143228
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- D'Youville College
Parkinson Disease, Gaucher Disease
Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism
The purpose of this study is to determine if participants have changes in dopamine cells in their brain using DaTSCAN™ brain imaging.
- Conditions
- Parkinson Disease, Gaucher Disease, Idiopathic Rapid Eye Movement Sleep Disorder
- Trial name
- NCT01358474
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sleep Disorder, ADHD
Sleep Patterns in Children and Adolescents With ADHD
This study is aimed to find out Sleep profile differences in children and adolescents with and without ADHD,Relationship between sleep profile disturbance and ADHD symptoms, Impact of sleep disturbance on cognition functions and…
- Conditions
- Sleep Disorder, ADHD, Cognitive Change
- Trial name
- NCT03737552
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Attention Deficit Hyperactivity Disorder Symptoms
Implementation Strategies for Caregiver and Teacher Use of Behavioral Interventions: Aim 2
The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support caregivers in using behavioral interventions for children with hyperactive…
- Trial name
- NCT07321327
- Testing
- Positive Behavior Management Toolkit for Caregivers, Positive Behavioral Management Toolkit for Teachers
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia