Clinical trials: Degenerative Joint Disease
Osteo Arthritis Knee, Osteoarthritis
The Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study
Many individuals with osteoarthritis (OA) (up to 45%) are referred to an orthopaedic surgeon for a joint replacement prematurely or will not be candidates for surgery.
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Hip Arthritis
- Trial name
- TEAM (NCT04544904)
- Testing
- PAARx, JM
- Where
- Canada
- Volunteers
- 356 people
- Sponsor
- Western University, Canada
Osteoarthritis Metacarpophalangeal Joint, Rheumatoid Arthritis Metacarpophalangeal Joint
Metacarpophalangeal Joint Prostheses in Hand Surgery.
The primary working hypothesis of this study is whether KeriFlex® metacarpophalangeal joint prostheses provide an equivalent result to Swanson finger joint implants in patients with rheumatoid arthritis or post-traumatic…
- Trial name
- FLEX (NCT06154421)
- Testing
- Metacarpophalangeal joint prostheses
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Waldfriede Hospital
Degenerative Joint Disease of Shoulder
Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)
The main purpose of this research is to find out if a treatment called cryoneurolysis can reduce pain after reverse total shoulder replacement surgery. This treatment uses cold to temporarily block a nerve in the shoulder.
- Trial name
- NCT07125833
- Testing
- Cryoneurolysis, No cryoneurolysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Osteoarthritis, Knee, Osteoarthritis, Hip
Improve Osteoarthritis Care
The purpose of The Improve Osteoarthritis Care study is to improve the quality of osteoarthritis care in Norwegian primary care, by increasing the use of recommended treatment modalities and improving patient access to…
- Trial name
- NCT04670549
- Testing
- Implementation of treatment guidelines
- Where
- Norway
- Volunteers
- 1,541 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis, Knee
Development of Spin-lock and FSE Acquisitions Based 3D Quantitative Biochemical Imaging for Osteoarthritis
In Hong Kong, joint diseases are common health problems as identified by the Elderly Health Service under the Department of Health. It accounts for most of the disability of the elderly in Hong Kong.
- Trial name
- NCT04431752
- Testing
- Magnetic Resonance Imaging Scan
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Angioembolization in Knee Osteoarthritis
Embolization of Genicular Arteries for Treatment of Symptomatic Knee Osteoarthritis
To evaluate the efficacy and safety of genicular artery embolization in patients with symptomatic knee osteoarthritis refractory to conservative treatment.
- Trial name
- NCT07736248
- Testing
- genicular artery embolization, Calibrated microspheres (100-300 µm), Microcatheter
- Volunteers
- 30 people
- Sponsor
- Assiut University
Osteo Arthritis Shoulders
BMA vs Cortisone for Glenohumeral Osteoarthritis
This randomized trial seeks to investigate the difference if any between cortisone injection versus bone marrow aspirate injection in the glenohumeral joint of patients with confirmed osteoarthritis.
- Trial name
- BMAC (NCT03580148)
- Testing
- Cortisone, Bone Marrow Aspirate
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Women's College Hospital
Knee Osteoarthritis
Robotic Assisted vs Custom Made Total Knee Arthroplasty
The goal of this clinical trial is to compare Robotic Assisted, functionally aligned vs Custom Made Total Knee Arthroplasty in patients with knee osteoarthritis.
- Trial name
- Knieathlon (NCT06280352)
- Testing
- Custom made Total Knee Arthroplasty, Functionally aligned robotically assisted total knee arthroplasty
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Austrian Workers Compensation Board Styria
Hip Arthrosis
Capsulectomy vs Capsulotomy in Total Hip Arthroplasty. Clinical Outcomes and Proprioception Evaluation
The purpose of our study is to evaluate the differences in functional activities and proprioception after surgery in subjects who underwent hip prosthesis implant with capsulotomy or capsulectomy.
- Trial name
- NCT02749058
- Testing
- Capsulectomy in Direct Anterior Total Hip Arthroplasty, Capsulotomy in Direct Anterior Total Hip Arthroplasty
- Where
- Italy
- Volunteers
- 94 people
- Sponsor
- IRCCS San Raffaele
Osteo Arthritis Knee
Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis
This randomized controlled trial aims to evaluate the effectiveness of combining intermittent hypoxia-hyperoxia therapy (IHHT) with conventional physical therapy in improving pain, function, gait, balance, and general health…
- Trial name
- NCT06965946
- Testing
- Intermittent Hypoxia-Hyperoxia Therapy (IHHT), Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Medical University Peshawar
Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant)
The NUsurface® Meniscus Implant SUN Clinical Trial is a multi-center, single-arm, prospective, open label, non-randomized, observational clinical trial to gather safety and probable clinical benefit data on the NUsurface®…
- Trial name
- SUN (NCT02483988)
- Testing
- NUsurface® Meniscus Implant
- Where
- 13 sites in United States
- Volunteers
- 115 people
- Sponsor
- Phoenix Kinetics
Osteoarthritis
The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis
Patients will be randomized into the control or intervention group. Based on patient preference, the intervention group will be trained for one hour in either individual or group format on vegan diet.
- Trial name
- NCT01939262
- Testing
- Limitation of Animal Fat and Protein in the Diet, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Knee Osteoarthritis
Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty
This study will attempt to draw relationships between the soft-tissue related complications contributing to early TKA revision and the loading and positional patterns from intraoperative tibial trial sensors.
- Trial name
- NCT03023410
- Testing
- VERASENSE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Orthosensor, Inc.
Adult ALL, Healthy
Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
The proposed study evaluates the effect of medial and lateral wedges and carbon fiber custom dynamic orthoses (CDOs) on lower limb forces and motion during walking.
- Trial name
- CDOKNEEpilot (NCT05209360)
- Testing
- Medial or Lateral Wedge, Carbon Fiber Custom Dynamic Orthosis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
CPPD - Calcium Pyrophosphate Deposition Disease, Gout
The Orienting Study
This study at IRCCS Galeazzi - Sant'Ambrogio Hospital involves patients with gout, CPPD, and osteoarthritis as a control group. Patients will receive routine care with regular clinical, laboratory, and imaging assessments every…
- Trial name
- ORIENTING (NCT07504146)
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Chronic Pain, Fibromyalgia
Chronic Pain, Couples, & Physical Activity
Chronic pain affects more than 50 million adults in the United States and is estimated to cost the nation more than $560 billion dollars each year.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04077164
- Testing
- No intervention, observational only.
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Illinois Institute of Technology
Osteoarthritis
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip.
- Trial name
- NCT02844764
- Testing
- [StroMed + platelet rich plasma (PRP)]
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- VivaTech International, Inc.
Trapeziometacarpal Osteoarthritis
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of Trapeziometacarpal Osteoarthritis
The objective of this clinical trial is to evaluate whether a human umbilical cord amniotic membrane allograft can serve as an interposition implant in the surgical treatment of trapeziometacarpal osteoarthritis.
- Trial name
- NCT07435571
- Testing
- with SclerFIX
- Where
- 4 sites in France
- Volunteers
- 22 people
- Sponsor
- TBF Genie Tissulaire
Osteo Arthritis Knee
"Ready-to-use" Intra-articular Formulation of Mesenchymal Stromal Cells
The goal of this clinical trial is to compare a newly developed off-the-shelf cryopreserved "ready to inject" Mesenchymal Stem Cell (MSC) product with the usual MSC preparation the investigators have used in knee osteoarthritis…
- Trial name
- PANLAR-II (NCT05751564)
- Testing
- "Ready to inject" Umbilical cord-derived Mesenchymal Stromal Cell (MSC) product, Resuspended Umbilical cord-derived Mesenchymal Stromal Cell (MSC) product
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Hip Osteoarthritis
Turkish Validation of the HOOS-12
The Hip Disability and Osteoarthritis Outcome Score-12 (HOOS-12) is a short patient-reported outcome measure developed to assess pain, function, and hip-related quality of life in individuals with hip osteoarthritis.
- Trial name
- NCT07770971
- Testing
- Patient-Reported Outcome Assessment
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.