Clinical trials: Degenerative Joint Disease
Knee Osteoarthritis
The Feasibility And Efficacy Of A Telerehabilitation Program For People With Knee Osteoarthiritis In Sri Lanka
it will be 8 week zoom program of exercises for knee osteo arthritis. participant will be selected according to elegibilty criteria. pre and post measurements will be obtained. then feasibility and efficacy will be assesed.
- Trial name
- NCT06268925
- Testing
- Exercises
- Where
- Sri Lanka
- Volunteers
- 14 people
- Sponsor
- University of Peradeniya
Knee Osteoarthritis
Clinical Investigation to Compare the Safety and Efficacy of Cellular Matrix to Those of Ostenil® Plus and to Those of PRP Only
Platelet-rich plasma (PRP) is an autologous product prepared from the patient's own blood, representing a powerful source of platelet-derived growth factors, particularly useful in the field of regenerative medicine.
- Trial name
- NCT02964143
- Testing
- Cellular Matrix / A-CP HA, Ostenil® Plus, RegenKit-BCT-1
- Volunteers
- 306 people
- Sponsor
- Regen Lab SA
Osteoarthritis Of Knee
Evaluating the Effectiveness of Using a Home Laser Device to Treat Patients With Knee Osteoarthritis
Osteoarthritis is a degenerative disease affecting joint cartilage and its surrounding tissue. It is the leading cause of disability in the elderly.
- Trial name
- NCT06773676
- Testing
- B-Cure laser pro
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Barzilai Medical Center
Knee Osteoarthritis, Blood Loss
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Trial name
- NCT05099276
- Testing
- Tranexamic Acid Pill
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the Summit™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208390
- Testing
- Summit Tapered Hip System
- Where
- 5 sites in China, Hong Kong and 3 more
- Volunteers
- 275 people
- Sponsor
- DePuy International
Osteo Arthritis Knee, Movement Disorders
Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients With Knee Osteoarthritis
Individuals with knee osteoarthritis are one of the groups most affected by musculoskeletal disorders and experience pain and mobility limitations that significantly limit their daily living activities.
- Conditions
- Osteo Arthritis Knee, Movement Disorders, Physical Disability, Knee Osteoarthritis
- Trial name
- NCT06527313
- Testing
- Movement Mobilization Concept, Exercise and Tape, Special Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istinye University
Knee, Osteoarthritis
Amniotic Suspension Allograft Injection for Knee Osteoarthritis
There have been few clinical trials on ASA for the treatment of knee osteoarthritis, and there is currently no literature reporting the optimal treatment dosage.
- Trial name
- ASAIKO (NCT06704893)
- Testing
- ASA injection 40 mg group, ASA injection 20 mg group, HA injection group
- Where
- 2 sites in Taiwan
- Volunteers
- 160 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Arthroplasty, Total, Osteoarthritis
Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial
Given the benefits of genicular nerve radiofrequency ablation (RFA) in improving pain and functional status in non-surgical patients with knee osteoarthritis as well as the high prevalence of postoperative pain from total knee…
- Conditions
- Knee Arthroplasty, Total, Osteoarthritis, Radiologic Tibiofemoral Osteoarthritis
- Trial name
- NCT02947321
- Testing
- Genicular Nerve RFA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Osteoarthritis
Medacta GMK Sphere® Multicenter Post-Market Outcomes Study
This study is to average Forgotten Knee Score (FJS) of those patients receiving the Medacta GMK Sphere® knee at the two and five year time points.
- Trial name
- NCT02501733
- Testing
- Medacta GMK Sphere® Medial Knee Prosthesis
- Where
- 5 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Hand Osteoarthritis
Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin
Osteoarthritis is the most common form of arthritis worldwide. Specifically, osteoarthritis of the hands affects millions of people and is a major cause of hand disability and pain.
- Trial name
- DUPRO (NCT02612233)
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Total Knee Arthroplasty, Osteoarthritis
Kinematic Analysis: Posterior Stabilized, Fixed Bearing Total Knee Arthroplasty With Attune Knee System - Phase 2
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal…
- Trial name
- NCT02613338
- Testing
- DePuy Attune posterior stabilizing fixed bearing knee system
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- The University of Tennessee, Knoxville
Symptomatic Hip Osteoarthritis
The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis
To demonstrate the difference in terms of symptomatic efficacy between ADANT® sodium hyaluronate and placebo following an intra-articular injection in patients with symptomatic osteoarthritis of the hip.
- Trial name
- NCT00330135
- Testing
- Sodium hyaluronate
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Daiichi Sankyo
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
TracPatch in Total Knee Arthroplasty
Total Knee Arthroplasty is becoming an increasingly common operation. An important part of a successful overall patient outcome is regaining functional range of motion after surgery.
- Trial name
- NCT03466476
- Testing
- Consensus TracPatch
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Osteoarthritis
Group Physical Therapy for Knee Osteoarthritis
Osteoarthritis (OA) is a common cause of pain and disability. Physical therapy is a key part of treatment for OA, but VA Medical Centers are often limited in their capacity to provide physical therapy services for veterans with…
- Trial name
- NCT00642772
- Testing
- Group Physical Therapy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Obesity (Disorder), Knee Osteoarthritis (Knee OA)
Effects of Resveratrol Supplementation Combined With a Low-Calorie Diet in Postmenopausal Women With Obesity and Knee Osteoarthritis
Obesity is a major modifiable risk factor for knee osteoarthritis and is associated with chronic low-grade inflammation, pain, functional impairment, and cartilage degradation.
- Trial name
- ERSOKO (NCT07634302)
- Testing
- Trans-resveratrol extract from Polygonum Cuspidatum, Low-Calorie Diet
- Where
- Russia
- Volunteers
- 97 people
- Sponsor
- Federal State Budgetary Scientific Institution
Osteoarthritis, Knee
Comparison of Meniscus Extrusion Between Preoperative and Postoperative MOWHTO Using Ultrasonographic Assessment
The purpose of this study is to measure the changes in the medial and lateral meniscus extrusion of the knee joint before and after surgery using ultrasound in patients who undergo medial opening wedge high tibial osteotomy, and…
- Trial name
- NCT04719195
- Testing
- Meniscus extrusion ultrasonogrphic evaluation
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- The Catholic University of Korea
Knee Osteoarthritis, Muscle Tightness
Effects of Dynamic Soft Tissue Mobilization in Reducing Hamstring Tightness in Knee Osteoarthritis
The objective of this randomized control trial is to evaluate the effectiveness of dynamic soft tissue mobilization in comparison with the proprioceptive neuromuscular facilitation (hold-relax) technique in reducing hamstring…
- Conditions
- Knee Osteoarthritis, Muscle Tightness, Range of Motion, Dynamic Stretching
- Trial name
- NCT04925895
- Testing
- Dynamic soft tissue mobilization, Proprioceptive neuromuscular facilitation stretching, Cryotherapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Dow University of Health Sciences
Knee Osteoarthritis, Low Level Laser Therapy
Low-Level Laser Therapy in Knee Osteoarthritis: Effects on Clinical Outcomes, Femoral Cartilage Thickness and Regional Sarcopenia
It was designed as a single-center, prospective, randomized controlled study. The study consists of two groups. Both groups of patients will receive a conventional home based exercise program.
- Conditions
- Knee Osteoarthritis, Low Level Laser Therapy, Regional Sarcopenia, Exercise Theraphy
- Trial name
- NCT07078877
- Testing
- home based exercise, Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara Etlik City Hospital
Knee Osteoarthritis (Knee OA)
Knee OsteoArthritis Long-term Assessment
The goal of this clinical study is to learn if Hydrogel OA 2% injection is safe and whether it works to improve symptoms of diagnosed knee osteoarthritis in adults when compared to Hyaluronic Acid (Durolane), a treatment that is…
- Trial name
- KOALA (NCT06839222)
- Testing
- Hydrogel OA 2%, Hyaluronic Acid (Durolane)
- Where
- 5 sites in Belgium
- Sponsor
- Allegro NV/SA
Osteoarthritis
Blocking Extracellular Galectin-3 in Patients With Osteoarthritis
The proposed study is a pilot, double-blind, randomized clinical trial comparing galectin-3 inhibition with MCP to placebo for the treatment of knee osteoarthritis.
- Trial name
- NCT02800629
- Testing
- Modified Citrus Pectin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.