Clinical trials: Degenerative Osteoarthritis
Knee Osteoarthritis
Comparison of Soft Tissue Techniques on Hamstring Flexibility Knee Osteoarthritis
The aim of this research is to compare the effects of Graston Technique, active release technique and PNF stretching on hamstring flexibility in Patients with Knee Osteoarthritis.
- Trial name
- NCT05125289
- Testing
- Graston technique group, Active release technique group, Proprioceptive Neuromuscular Facilitation stretching group
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Effects of Semi-standarized Acupuncture in Chronical Symptomatic Osteoarthritis of the Knee Through: A Randomized Controlled Trial
Introduction: Knee osteoarthritis is a long-term rheumatic disease with a significant impact on the patient's quality of life and the socio-economic development of societies.
- Trial name
- NCT05096806
- Testing
- Acupuncture, TENS
- Volunteers
- 56 people
- Sponsor
- Universitat de Girona
Knee Osteoarthritis (Knee OA), Total Knee Arthroplasty
Early Clinical Benefits of Robot-Assisted vs Manual Total Knee Arthroplasty (RATKA-EARLY)
This study, called the RATKA-EARLY trial, was designed to compare two surgical techniques used in total knee replacement (also known as total knee arthroplasty or TKA).
- Trial name
- RATKA-EARLY (NCT07078149)
- Testing
- Robotic-assisted TKA (RATKA)., Conventional manual TKA (mTKA)
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitario Santa Cristina
Wrist Arthritis, Wrist Arthropathy
Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE)
This randomized clinical trial (RCT) aims to compare clinical and radiographic outcomes of different partial wrist fusion techniques in participants with post-traumatic wrist arthritis.
- Conditions
- Wrist Arthritis, Wrist Arthropathy, Scapholunate Advanced Collapse, Scaphoid Nonunion
- Trial name
- PARTE (NCT04580225)
- Testing
- Four-Corner Arthrodesis, Three-Corner or Capitolunate Arthrodesis with Triquetral Excision
- Where
- 5 sites in Canada
- Volunteers
- 170 people
- Sponsor
- University of Alberta
Osteoarthritis
Postural Analysis in Patients With Knee Osteoarthritis
Osteoarthritis is the result of the degeneration of the cartilage to articulate, being currently considered as having an multifactorial cause.The knees are one of the affected joints more due to overload that constitutes the main…
- Trial name
- NCT01031576
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteoarthritis, Total Knee Arthroplasty
Use of Cold and Compression Therapy With Total Knee Replacement Patients
The purpose of the study is to evaluate the effectiveness of a device that delivers cold and intermittent compression as compared to ice and compressive wraps on patients who have undergone knee replacement.
- Trial name
- NCT00712816
- Testing
- Game Ready Injury Treatment System (CoolSystems Inc.), Ice with compressive bandages
- Where
- 11 sites in United States, Australia
- Volunteers
- 224 people
- Sponsor
- CoolSystems, Inc.
Arthropathy of Hip Joint, Osteoarthritis, Hip
Opioid Free and Therapy Minimized Advantages Using HANA Table for Total Hip Arthroplasty
To prove that anterior approach total hip arthroplasty using the HANA table can be performed with little, if any, need for opioids using a combination of education, optimized pre op and post op pain protocols and optimized…
- Trial name
- NCT03790306
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- St. Elizabeth Medical Center, Utica, NY
Osteoarthritis, Knee, Healthy
Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects
This is a study of participants that will receive an intravenous (IV) infusion of oxytocin (naturally occurring hormone that is made in the brain).
- Trial name
- NCT04431206
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis
Effective Rehabilitation of Patients Operated With Total Knee Arthroplasty
The purpose of this study is to investigate the effect of maximal strength training (MST) compared to standard rehabilitation in patients operated with total knee arthroplasty.
- Trial name
- NCT01877733
- Testing
- Maximal strength training
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Norwegian University of Science and Technology
Femoracetabular Impingement
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery
The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population.
- Trial name
- DoD FAI-2 (NCT04243447)
- Where
- 13 sites in United States, Canada
- Volunteers
- 747 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis, Knee
Physiotherapy and Therapeutic Education After Total Knee Arthroplasty.
The purpose of this study is to test whether adding a treatment using pain neuroscience education (PNE) and coping skills training (CST) to usual care, in subjects with knee osteoarthritis and pain catastrophizing, who are…
- Trial name
- NCT03198247
- Testing
- Usual care, PNE + CST
- Where
- Spain
- Sponsor
- Centro Universitario La Salle
Osteoarthritis
Osteoarthritis Topical Treatment
This is a phase 2a clinical trial performed to evaluate the efficacy of a topical treatment of ibuprofen compared to the use of a placebo topical treatment. A multi-center, double-blinded, randomized placebo controlled study.
- Trial name
- ANTIPAIN (NCT01496326)
- Testing
- Ibuprofen
- Where
- 5 sites in Switzerland
- Volunteers
- 75 people
- Sponsor
- BioChemics, Inc.
Osteoarthritis, Knee, Osteoarthritis, Hip
Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip
The primary objective of this study is to evaluate the effectiveness of REGN475 compared to placebo in participants with pain due to osteoarthritis (OA) of the knee or hip and a history of inadequate joint pain relief or…
- Trial name
- NCT02447276
- Testing
- REGN475
- Where
- 72 sites in United States
- Volunteers
- 421 people
- Sponsor
- Regeneron Pharmaceuticals
Osteoarthritis, Knee
Dry Needling and Exercise Program in Osteoarthritis
Osteoarthrosis (OA) is a chronic degenerative disease that affects the joints, knee OA is the most prevalent type, affecting 265 million people worldwide, more than 40% of adults over 45 years of age, being one of the greatest…
- Trial name
- NCT06816940
- Testing
- CONTROL GROUP:, EXPERIMENTAL GROUP
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Manuel Albornoz Cabello
Knee Osteoarthritis
Effects of Mindfulness-Based Stress Reduction on Knee Osteoarthritis
The purpose of this study is to see if stress reduction can lead to less pain due to knee osteoarthritis. To do this the investigators will compare two types of stress reduction modalities, Mindfulness-Based Stressed Reduction…
- Trial name
- MBSR on KOA (NCT03527849)
- Testing
- Mindfulness-Based Stress Reduction, Health Enhancement Program
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Davis
Hip Osteoarthritis
Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis
This is a randomized, double-blind and placebo-controlled study to evaluate the efficacy of zoledronic acid on the biologic incorporation of cementless hip prosthesis in postmenopausal female patients.The study population…
- Trial name
- NCT01218035
- Testing
- zoledronic acid
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- Turku University Hospital
Gastric Ulcer, Duodenal Ulcer
Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID
The purpose of this study is to assess the efficacy of esomeprazole (D961H) 20 mg versus placebo once daily for up to 24 weeks of treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily…
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- NCT00542789
- Testing
- Esomeprazole
- Where
- 39 sites in Japan
- Volunteers
- 343 people
- Sponsor
- AstraZeneca
Osteoarthritis, Fibromyalgia
Assessing Central Aspects of Pain
BACKGROUND: Chronic pain continues for more than 12 weeks despite medication or treatment. Chronic pain is the main symptom of muscle and joint problems, rarely explained by damage to the muscle and joints alone.
- Conditions
- Osteoarthritis, Fibromyalgia, Chronic Low Back Pain, Inflammatory Arthritis
- Trial name
- AsCent (NCT06518278)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Nottingham
Knee Osteoarthritis
Sinew Acupuncture for Knee Osteoarthritis
The study aims to exam whether sinew acupuncture can relieve pain and symptoms of KOA and improve functional movement by Visual Analog Scale (VAS), Western Ontario and McMasters University Osteoarthritis Index (WOMAC), Timed up…
- Trial name
- NCT03099317
- Testing
- Sinew acupuncture
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- The University of Hong Kong
Osteoarthritis, Knee
Study of SI000413 in Knee Osteoarthritis Patients
The purpose of this study is to evaluate efficacy and safety of SI000413 in patients with knee osteoarthritis by orally administration and to determine optimal dose.
- Trial name
- NCT01525758
- Testing
- SI000413, microcrystalline cellulose
- Where
- 3 sites in South Korea
- Volunteers
- 152 people
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
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