Clinical trials: Degenerative Osteoarthritis
Osteoarthritis, Knee
Effects of Multicomponent Exercise on Subchondral Bone and Cartilage in Postmenopausal Women With Knee Osteoarthritis
Today, osteoarthritis (OA) is considered a whole-organ disease that is amenable to prevention and treatment in the early stages.
- Trial name
- LuRu2 (NCT06173193)
- Testing
- Multicomponent exercise regimen, Standard rehabilitative management
- Where
- Finland
- Volunteers
- 103 people
- Sponsor
- University of Jyvaskyla
Pain, Physical Function
Osteoarthritis Outcomes in Different Ages
We aim to study if there are differences in outcomes between different age groups for persons with knee or hip osteoarthritis during treatment in digitally delivered exercise and education treatment.
- Conditions
- Pain, Physical Function, Age
- Trial name
- NCT05208463
- Testing
- Joint Academy
- Where
- Sweden
- Volunteers
- 14,610 people
- Sponsor
- Joint Academy
Knee Osteoarthritis (Knee OA)
Effects of Core Stabilization Exercises in Female Patients With Gonarthrosis
Osteoarthritis (OA) is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, primarily affecting weight-bearing joints.
- Trial name
- NCT07482332
- Testing
- 10 days of conventional physiotherapy (Hot Pack, TENS, Ultrasound) and 6 weeks of routine knee exercises, Six weeks of core stabilization exercises.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Perilunate Dislocation
Development of Automated Real-time Algorithms for Detection of Dislocation of the Carpus
Perilunate dislocation of the carpus is a serious lesion of the wrist which is defined by a total loss of contact of the articular surfaces capito-lunar, scapholunate and lunate-triquetral.
- Trial name
- CARPUS (NCT05458921)
- Where
- France
- Volunteers
- 10,100 people
- Sponsor
- University Hospital, Strasbourg, France
Bilateral Knee Osteoarthritis
Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA
This is a randomized, open-label, parallel group study to compare systemic exposure of triamcinolone acetonide following administration into both knees of either FX006 or TAcs.
- Trial name
- NCT03378076
- Testing
- FX006 32 mg, TAcs 40 mg
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Amputation, Osteo Arthritis Knee
Femoral Cartilage Thickness In Patients With Lower Limb Amputation
The aim of the study to investigate any relation with functional parameters and femoral cartilage thickness evaluation by ultrasonography in lower extremity amputate individuals.
- Trial name
- NCT04422717
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Osteoarthritis, Overweight and Obesity
Fit and Strong! Plus Comparative Effectiveness Trial
This randomized controlled trial is comparing outcomes of customary Fit and Strong!, to Fit and Strong! Plus, an enhanced version of the program that incorporates weight management.
- Trial name
- NCT03180008
- Testing
- Fit and Strong!, Fit and Strong! Plus
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Osteoarthritis, Mindfulness
A Mindfulness Program (MBSR) in the Management of Symptomatic Hip and Knee Osteoarthritis
Symptomatic osteoarthritis (OA) is the most common joint disease and the leading cause of disability in industrialized countries.
- Conditions
- Osteoarthritis, Mindfulness, MBSR
- Trial name
- MINDFULNESS_OA (NCT03644615)
- Testing
- Mindfluness and usual care, Usual care
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis Pain
Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee
To evaluate the efficacy of ACP-044 compared with placebo in the treatment of pain associated with osteoarthritis of the knee
- Trial name
- NCT05008835
- Testing
- ACP-044 Dose A, ACP-044 Dose B
- Where
- 34 sites in United States
- Volunteers
- 61 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Osteoarthritis, Knee
Prospective Post-Market Data Collection on Patients With Knee OA and Treated With nSTRIDE APS
This study will document treatment effects, changes in quality of life, procedure complications, adverse events, healthcare resource utilization, and further needed intervention(s) following treatment with nSTRIDE autologous…
- Trial name
- PROGRESS III (NCT02580643)
- Testing
- APS
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- Zimmer Biomet
Osteoarthritis (OA) of the Knee
Kinesio Taping After Platelet-Rich Plasma Treatment in Individuals With Knee Osteoarthritis
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine…
- Trial name
- NCT07773324
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Agri Ibrahim Cecen University
Hip Osteoarthritis, Hip Disease
Treatment of Osteoarthritis of the Hip Joint With Intra-articular Injection of Microfractured Autologous Adipose Tissue Containing Mesenchymal Stromal Cells.
The aim of the study is to evaluate the safety and efficacy up to 12 months of MF-AT in the echo-guided infiltrative treatment of hip OA through clinical, subjective and objective evaluations.
- Trial name
- Lipo-Hip (NCT05465096)
- Testing
- Micro-fragmented adipose tissue injection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Total Knee Arthroplasty Comparing Cementless to Cemented Fixation
The purpose of this study is to determine if there are any clinical or radiographic differences in cemented and cementless fixation in total knee replacement.
- Trial name
- NCT01335438
- Testing
- Cementless (Nexgen), Cemented (Nexgen)
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Young Hoo Kim
Knee Osteoarthritis, Task Performance and Analysis
Knee Osteoarthritis, Motor Control, Risk of Falls and Virtual Reality
The goal of this clinical trial is to learn about knee osteoarthritis, functionality, and risk of falls in community-dwelling adults aged 60 years and older.
- Conditions
- Knee Osteoarthritis, Task Performance and Analysis, Accidental Falls, Virtual Reality
- Trial name
- NCT06362785
- Testing
- Virtual Reality, Therapeutic exercise
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Thumb Osteoarthritis
Ligament Reconstruction Weilby vs Simple Trapeziectomy
There is currently no consensus on the best surgical approach for carpometacarpal osteoarthritis treatment. Simple trapeziectomy (TI) or trapeziectomy with ligament reconstruction tendon interposition (LRTI) are both accepted…
- Trial name
- WEILBY (NCT03858946)
- Testing
- Simple trapeziectomy, Weilby
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Knee Osteoarthritis
Autologous Adipose Stem Cells and Platelet Rich Plasma Therapy for Patients With Knee Osteoarthritis
Adipose stem cells and platelet rich plasma can regenerate the injured cartilage.
- Trial name
- NCT02142842
- Testing
- Autologous adipose tissue stromal vascular fraction and platelet rich plasma
- Where
- 3 sites in Vietnam
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Science Ho Chi Minh City
Degenerative Joint Disease, Osteoarthritis
PEAK PlasmaBlade 4.0 Versus Traditional Electrosurgery in Total Knee Replacement.
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade 4.0 during total knee replacement; to monitor and record post-operative pain, activity level, narcotic consumption, adverse…
- Trial name
- PRECISE (NCT01081886)
- Testing
- PEAK PlasmaBlade 4.0, Traditional Electrosurgery with scalpel
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Medtronic Surgical Technologies
Knee Osteoarthritis
Taping Versus Conventional Physiotherapy in Knee Osteoarthritis
The purpose of this study is to determine the effects of kinesio taping versus conventional physiotherapy in women with knee osteoarthritis.
- Trial name
- NCT05606354
- Testing
- Intervention group
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Osteoarthritis
DePuy Global Unite Shoulder System
To collect medium to long-term survivorship implant outcomes on the DePuy Global Unite Shoulder System
- Trial name
- NCT02412397
- Testing
- Total Shoulder Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Knee
Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain
The purpose of this study is to evaluate the efficacy and safety of Transdermal therapeutic system (TTS) fentanyl patches (transdermal patch containing a drug that is put on the skin so the drug will enter the body through the…
- Trial name
- NCT01742897
- Testing
- TTS-fentanyl
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
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