Clinical trials: Deglutition Disorder
Swallowing Difficulties, Thirst
Effect of Cold Water Spray on Swallowing Difficulty, Pain, and Thirst After Thyroid Surgery
Dysphagia and thirst are common in the early period after thyroidectomy and negatively affect patient comfort. This study aims to evaluate the effect of cold water spray on dysphagia, pain during swallowing, and thirst after…
- Conditions
- Swallowing Difficulties, Thirst, Thyroidectomy
- Trial name
- CWS-THY (NCT07879404)
- Testing
- Cold water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Achalasia Cardia
Randomised Trial Between LHM Alone Vs LHM With Anterior Fundoplication In Achalasia Cardia
Back ground: Achalasia Cardia (AC) manifests with major symptom dysphagia. Surgery as the treatment modality relieves dysphagia in most of the patients.
- Trial name
- NCT03438838
- Testing
- Laparoscopic Heller's myotomy, Anterior Fundoplication
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Govind Ballabh Pant Hospital
GERD
A New System for GERD Diagnosis and Treatment
This is a pilot study measuring a new diagnosis and treatment system "EAISMLP" in adult patients with gastroesophageal reflux disease (GERD).
- Trial name
- EAISMLP (NCT03600974)
- Testing
- Stretta, Laparoscopic Nissen fundoplication, Probiotic Agent
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
Regurgitation, Gastric
Evaluation of the Tolerance and Safety of a New Partly Fermented Anti-regurgitation Infant Formula
A randomised, controlled, double-blind trial to evaluate the tolerance and safety of a new partly fermented anti-regurgitation infant formula containing prebiotics and locust bean gum in infants with regurgitation.
- Trial name
- Leopard (NCT03371615)
- Testing
- Anti-regurgitation infant formula
- Where
- 2 sites in Poland
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Reflux Episodes
TLESR-impedance Study in Patients
The purpose of the study is to compare frequency and content of reflux episodes in patients with gastroesophageal reflux disease.
- Trial name
- NCT00743444
- Testing
- AZD3355
- Volunteers
- 27 people
- Sponsor
- AstraZeneca
Gastroesophageal Reflux
Antireflux Efficacy of Hiatal Hernia Repairs in Sleeve Gastrectomy Patients
Gastroesophageal reflux (GR) occurrence or persistence following a sleeve gastrectomy (SG) can be correlated to several factors but it is clear that one of the key factors is a persistent hiatal hernia or laxity of the esophageal…
- Trial name
- NCT04433507
- Testing
- Sleeve gastrectomy, Hiatal Hernia repair
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Deglutition Disorder, Dysphagia
The Turkish Feeding/Swallowing Impact Survey
The purpose of this study is to test the reliability and validity of the Turkish Feeding/Swallowing Impact Survey among caregivers of pediatric patients with swallowing disorders.
- Conditions
- Deglutition Disorder, Dysphagia, Outcome Assessment, Quality of Life
- Trial name
- NCT03005093
- Testing
- CAREGIVERS, CHILDREN OF CAREGIVERS
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Proton Pump Inhibitors, Gastroesophageal Reflux Disease
Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision Aid
BACKGROUND: Proton pump inhibitors (PPIs) treat problems such as gastroesophageal reflux disease (GERD). In many patients with mild or moderate GERD, PPIs should be used for 1-2 months but are often continued longer…
- Trial name
- NCT02558049
- Testing
- Decision aid
- Where
- 3 sites in Canada
- Volunteers
- 12 people
- Sponsor
- University of Ottawa
Stroke, Dysphagia
Oral Neuromuscular Training in Stroke Patients With Dysphagia
This study aims to explore if oral neuromuscular training is superior to orofacial sensory-vibration stimulation in patients with oropharyngeal dysphagia.
- Trial name
- NCT04164420
- Testing
- Oral neuromuscular training and orofacial sensory-vibration, Orofacial sensory-vibration stimulation
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Stroke, Dysphagia
Liu-Zi-Jue Exercise Combined With Conventional Rehabilitation Treat Dysphagia in Post-stroke
In this study, a prospective, randomized controlled method was adopted, with patients with post-stroke dysphagia as the main research objects, applying "Liu-Zi-Jue" to the patients for rehabilitation intervention, and to explore…
- Trial name
- NCT05602922
- Testing
- Liu-Zi-Jue Exercise, Basic treatment +Swallowing rehabilitation training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Morbid Obesity, Acidosis
Intraoperative Fluid Management in Laparoscopic Bariatric Surgery
The objective of this study is to evaluate the effects of 'high' versus 'low' volume intraoperative fluid administration (Ringer Lactate, RL) on intra- and postoperative parameters, in obese patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Acidosis, Intra-Abdominal Abscess, Hemorrhage
- Trial name
- NCT00905502
- Testing
- Lactated Ringer's solution
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gastroesophageal Reflux Disease
Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescents
The purpose of this study was to assess the safety and effectiveness of once daily oral administration of dexlansoprazole delayed-release capsules in adolescent participants with symptomatic non-erosive gastroesophageal reflux…
- Trial name
- NCT01642602
- Testing
- Dexlansoprazole
- Where
- 64 sites in United States, Belgium and 6 more
- Volunteers
- 104 people
- Sponsor
- Takeda
Gastroesophageal Reflux
A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis
The purpose of this study is to evaluate whether Rebamipide facilitate the healing of inflamed mucosa as an adjuvant regimen in erosive reflux esophagitis (ERE).
- Trial name
- REPAIR (NCT02755753)
- Testing
- Lansoprazole, Rebamipide
- Where
- 5 sites in China, South Korea
- Volunteers
- 143 people
- Sponsor
- YongChan Lee
Dysphagia, Oropharyngeal, Swallowing Disorder
Validity and Reliability of the Turkish Version of the Sydney Swallow Questionnaire
Purpose of the study is the validity and reliability of the Turkish version of the Sydney Swallow Questionnaire (SSQ-T), so that it would be used as an assessment tool for Turkish dysphagia patients.
- Conditions
- Dysphagia, Oropharyngeal, Swallowing Disorder, Validation
- Trial name
- NCT04465903
- Testing
- Turkish Version of Sydney Swallow Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Dysphagia
Specialize Dysphagia Training and Knowledge/Competency of Nurses
The aim of this research is to determine the effect of specialized dysphagia training on knowledge and competency of nurses.
- Trial name
- NCT05626361
- Testing
- Dysphagia training, Reading material
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Laryngopharyngeal Reflux, Throat Pain
Anti-reflux Control to Decrease Post Tonsillectomy Pain
The study aims to determine if treating pediatric patients (age 7-17) for four weeks with omeprazole prior to tonsillectomy will decrease post tonsillectomy pain.
- Trial name
- NCT01777854
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants
Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates
Oral feeding of neonates while on nasal continuous positive airway pressure (NCPAP) is a common practice in many neonatal intensive care units (NICU) all over the country.
- Conditions
- Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants, Respiratory Aspiration, Newborn, Premature
- Trial name
- NCT02661256
- Testing
- NCPAP, Varibar® Thin Liquid Barium Sulfate for Suspension
- Volunteers
- 7 people
- Sponsor
- NYU Langone Health
Cough
Validation of Peptest™ for the Detection of Reflux in Cough
Chronic cough is a common presenting problem which has a significant impact on quality of life. Gastro-oesophageal reflux (GOR) is a common cause of chronic cough and reflux of stomach contents into the airways has been…
- Trial name
- NCT03851393
- Testing
- Induction of cough with inhaled citric acid, Peptest™ analysis of saliva pepsin, Peptest™
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Cerebral Palsy, Respiratory Function
Inspiratory Muscle Training in Children With Cerebral Palsy: Effects on Respiratory and Motor Functions
This study investigates the effect of inspiratory muscle training on respiratory parameters, trunk control, upper extremity function and swallowing in patients with cerebral palsy aged 5-18 years.
- Conditions
- Cerebral Palsy, Respiratory Function, Balance, Swallowing
- Trial name
- NCT07041593
- Testing
- Inspiratory muscle training and standard neurodevelopmental physiotherapy (SNP), Standard neurodevelopmental physiotherapy (SNP)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Sadık Emre ÇELEBİ
GERD
An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)
This study looks at the effect on basal and pentagastrin-stimulated acid output of 40 mg Esomeprazole (Nexium) administered orally and intravenously as a 15-minute infusion to people with symptoms of Gastroesophageal Reflux…
- Trial name
- NCT00629564
- Testing
- Esomeprazole
- Volunteers
- 60 people
- Sponsor
- AstraZeneca
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