Clinical trials: Deglutition Disorder
GERD, Esophagitis
Esophageal Monitoring Device for Assessing Mucosal Impedance
The investigators are looking at a novel approach to measuring gastroesophageal reflux disease (GERD) damage and reducing the need for costly and less optimal testing presently used for diagnostic and treatment purposes.
- Trial name
- NCT01556919
- Testing
- Standard of care endoscopy
- Where
- United States
- Volunteers
- 429 people
- Sponsor
- Vanderbilt University
Gastric Reflux, Gastro Esophageal Reflux
Gastric Reflux and Sinonasal Symptoms
The study is conducted to: study correlation between sinonasal troubles \& GERD Assess whether antireflux therapy improve state of sinus in patients complaining from reflux \& sinonasal symptoms
- Trial name
- NCT04105894
- Testing
- MSCT of nose and PNs, Swab from nasal and oral mucous discharge to evaluate presence of HCL and pepsin, medical treatment of GERD t
- Volunteers
- 40 people
- Sponsor
- Assiut University
Laryngopharyngeal Reflux
A New Nasopharyngeal pH Probe for Diagnosis of Laryngopharyngeal Reflux
The purpose of this study is to evaluate the utility of a minimally invasive nasopharyngeal pH probe for the diagnosis of laryngopharyngeal reflux (LPR) in children with airway compromise; to determine whether it is comparable to…
- Trial name
- NCT01308502
- Testing
- Dx-pH probe
- Where
- United States
- Sponsor
- Children's Hospital of Philadelphia
Stroke
Changes of Swallowing Function and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Therapy and Neuromuscular Electrical Stimulation in Stroke Patients With Dysphagia
1. The inter-rater and intra-rater reliability of sonography. 2. To explore that sonography is a clinically practical tool for assessing the changes of oropharyngeal muscles mass. 3.
- Trial name
- NCT04728737
- Testing
- swallowing therapy, IOPI therapy, neuromuscular electrical stimulation (NMES) therapy
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Gastroesophageal Reflux Disease (GERD)
Retrospective Observational Study on GERD Management in General Hospitals in Korea
A RetrospectiVe ObservatIoNal Study of a CurrEnt Status and its Management of GERD (GastroEsophageal Reflux Disease) in General HOspitals in Korea
- Trial name
- VINCERO (NCT06974903)
- Where
- South Korea
- Volunteers
- 13,750 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Refractory Reflux Esophagitis
Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux Esophagitis
The purpose of this study is to evaluate the efficacy and safety of E3810 tablets in patients with Proton Pump Inhibitor-resistant reflux esophagitis.
- Trial name
- NCT00770913
- Testing
- E3810
- Where
- 54 sites in Japan
- Volunteers
- 337 people
- Sponsor
- Eisai Co., Ltd.
Head and Neck Cancer
Nutritional Status and Barriers to Dietary Intake in Head and Neck Cancer Patients
The investigators hope to learn more about how side-effects of RT or RTchemo affect food intake and nutrition status.
- Trial name
- NCT00375180
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- AHS Cancer Control Alberta
Achalasia Cardia, Esophageal Cancer (EsC)
INCIDENCE, PREVALENCE AND OVERALL RISK OF ESOPHAGEAL CANCER IN ACHALASIA: A PROPENSITY-MATCHED POPULATION-BASED STUDY FROM A LARGE MULTICENTER DATABASE
Esophageal Achalasia has been investigated as a potential risk factor for esophageal cancer (EC). Longstanding disease, repeated treatment, age and male sex seem the most relevant risk factors, but no clear effect size estimation…
- Trial name
- RECAP (NCT07022886)
- Testing
- achalasia treatments
- Where
- Italy
- Volunteers
- 47,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Metabolic Syndrome, Severe Obesity
Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.
The aim of this study is to determine the feasibility and effectiveness of endoscopic anastomosis of sleeve gastrectomy to ileum with a lumen apposing metal stent (LAMS) after a failed sleeve gastrectomy.
- Conditions
- Metabolic Syndrome, Severe Obesity, Reflux, Gastroesophageal, Bariatric Surgery
- Trial name
- NCT06757296
- Testing
- Endoscopic SASI
- Where
- 3 sites in Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore Health Services
Oesophageal Reflux
Determination of the Left Paratrachéal Force Required to Occlude the Esophageal Entrance
Determine the force required to occlude the esophagus with a left paratracheal pressure
- Trial name
- NCT05214079
- Testing
- Left paratracheal pressure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liege
Anesthesia
Risk of Gastric Reflux During Tulip vs GMA(Glottis Mask Airway) Airway
Glottis mask airway (GMA) is supraglottic airway device and is frequently used in patients undergoing general anesthesia. However, gastroesophageal reflux remains a risk during ventilation through supraglottic airway devices.
- Trial name
- TUGGER (NCT06527352)
- Testing
- glottis mask airway, tulip shaped, classical shaped
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Air Force Military Medical University, China
Dysphagia, Stroke
NMES Plus Conventional Therapy for Stroke Dysphagia
Aim: The aim of this study is to investigate the effect of neuromuscular electrical stimulation (NMES) combined with traditional dysphagia therapy (TDT) in acute/subacute stroke patients with dysphagia.
- Trial name
- NCT07415785
- Testing
- neuromuscular electrical stimulation, traditional dysphagia therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chiayi Christian Hospital
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Obstructive Sleep Apnea, Reflux, Laryngopharyngeal
Prevalence of Pharyngolaryngeal Reflux in Patients Treated for Obstructive Sleep Apnea Syndrome
The aim of the study is to find, using validated and efficient tools, a laryngopharyngeal reflux in patients receiving polysomnography for suspected obstructive sleep apnea syndrome.
- Trial name
- RESTECH (NCT05110352)
- Testing
- Polysomnography, Pharyngeal ph-metry Restech, Peptest
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Elsan
Achalasia Cardia
Comparison of Balloon Dilatation and Per Oral Endoscopic Myotomy in Children With Achalasia Cardia
To compare the efficacy of balloon dilatation (BD) and per oral endoscopic myotomy (POEM) in improving the symptoms of children with achalasia in short and long term Presently most guidelines such as American Society for…
- Trial name
- NCT07167355
- Testing
- POEM, BALLOON DILATATION
- Volunteers
- 70 people
- Sponsor
- Asian Institute of Gastroenterology, India
Esophageal Dysmotility
Topical Bethanechol for Improvement of Esophageal Dysmotility
The purpose of this research project is to determine the effect of a drug called bethanechol on swallowing function in patients with Ineffective Esophageal Motility (IEM).
- Trial name
- NCT01031043
- Testing
- Bethanechol
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Augusta University
Gastroesophageal Reflux
SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01)
The aim of this study is to evaluate the efficacy of a new thickened formula on regurgitation
- Trial name
- SWAN (NCT02710955)
- Testing
- Thickened infant formula
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- United Pharmaceuticals
Mitral Valve Stenosis With Incompetence or Regurgitation
The Effects of Levosimendan During Mitral Valve Surgery
The effects of levosimendan on renal function in patients with low ejection fraction undergoing mitral valve surgery will be investigated in a prospective, double-blinded, randomized clinical trial using serum creatinine…
- Trial name
- NCT01969071
- Testing
- Levosimendan, Dobutamine
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Dysphagia
Intermittent Oro-esophageal Tube on Feeding Hesitancy in Stroke Patients
The aim of this clinical trial is to compare Feeding Hesitancy of ischemic stroke patients who receive enteral nutrition support through either Intermittent Oro-esophageal Tube or Nasogastric Tube.
- Trial name
- NCT06312371
- Testing
- Intermittent Oro-esophageal Tube Feeding, Nasogastric Tube Feeding
- Volunteers
- 80 people
- Sponsor
- Muhammad
Parkinson's Disease and Parkinsonism, Dysphagia
Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism.
- Trial name
- NCT07153692
- Testing
- tDCS, Conventional Dysphagia Treatment
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Wang Ping
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.