Clinical trials: Deglutition Disorder
Laryngeal Cleft, Dysphagia
Injection Versus Suture Repair of Laryngeal Clefts
The purpose of the study is to learn more about a procedure that may be helpful for the participant's swallowing issues. The investigators are hoping to find out if one type of procedure is the same or better than another type of…
- Trial name
- NCT07057258
- Testing
- Endoscopic suture repair, Injection laryngoplasty
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Oregon Health and Science University
Swallowing Disorder.Other Specified
Electromagnetic Therapy for Cervicogenic Dysphagia
Cervicogenic dysphagia (CD) is a swallowing disorder in patients with cervicogenic pathology. Pulsed electromagnetic therapy (PEMT) is a widely utilized therapeutic modality.
- Trial name
- NCT07765043
- Testing
- The pulsed electromagnetic field treatment program plus the swallowing resistance training program
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Dysphagia, Pneumonia
Oropharyngeal Dysphagia in Patients With Community Acquired Pneumonia
This study investigates relationship between community acquired pneumonia and oropharyngeal dysphagia in patients admitted to a department of respiratory medicine in Northern Denmark.
- Trial name
- NCT01974089
- Testing
- Dysphagia
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Regionshospital Nordjylland
Gastroesophageal Reflux Disease, Hiatal Hernia
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)
Laparoscopic Nissen Fundoplication has established itself as the procedure of choice in the surgical management of the majority of patients suffering from gastroesophageal reflux disease (GERD).
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Barrett's Esophagus, Esophagitis
- Trial name
- NCT00872755
- Testing
- Nissen, Gastropexy
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- G. Hatzikosta General Hospital
Deglutition Disorders
The Aspirometer: A Noninvasive Tool for Detecting Aspiration Aim 3
This investigation evaluates the effectiveness of a device called the Aspirometer, which uses high resolution cervical auscultation (HRCA), in detecting when food or liquids enter the airway (aspiration) of the person swallowing…
- Trial name
- NCT06637774
- Testing
- Aspirometer, Videofluoroscopic X-ray
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Dysphagia, Anxiety
Correlations Between Symptoms of Anxiety And/or Depression with Dysphagia Severity Level
The goal of this observational study is to know any CORRELATIONS BETWEEN SYMPTOMS OF ANXIETY AND / OR DEPRESSION WITH DYSPHAGIA SEVERITY LEVEL in is all of the new or ongoing patients with dysphagia in the Neurorehabilitation…
- Conditions
- Dysphagia, Anxiety, Depression
- Trial name
- NCT06587555
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Padjadjaran
Cancer
The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms"
The aim of the study is to identify how often gastrointestinal problems interfere with quality of life as a result of treatment for cancer with chemotherapy.
- Trial name
- FOCCUS (NCT02121626)
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Head and Neck Cancer, Dysphagia
Head and Neck Cancer Treatment Related Dysphagia
Cancers located in the upper aerodigestive tract of the head and neck region present unique management challenges due to the crucial functions in this anatomic region along with its anatomic density.
- Trial name
- NCT02657850
- Testing
- non- head and neck self reporting, head neck self reporting, provider reporting
- Where
- 9 sites in United States, Australia and 2 more
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Esophageal Reflux
The Effect of Chlorpromazine on Esophageal Sensitivity in Healthy Volunteers.
The effect of chlorpromazine (Largactil) on esophageal sensitivity will be investigated in this study. Overnight fasted subjects will be asked to fill out 2 questionnaires to assess the emotional status before their onset of the…
- Trial name
- NCT03183310
- Testing
- Chlorpromazine, Multimodal stimulation probe
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastroesophageal Reflux Disease
Prevalence and Impact in Work Productivity of Gastroesophageal Reflux Disease (GERD) in Primary Care Patients With Upper Gastrointestinal (GI) Symptoms Using GerdQ
The purpose of the study is to provide data on the GERD prevalence as percentage of patients with upper GI symptoms that are identified with GERD using the GerdQ Questionnaire.
- Trial name
- GerdQ-Greece (NCT00914342)
- Where
- 54 sites in Greece
- Volunteers
- 889 people
- Sponsor
- AstraZeneca
Oropharyngeal Dysphagia, Deglutition Disorders
Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia
Oropharyngeal dysphagia induces aspirations which could be responsible of aspiration pneumonia and denutrition. It could be present in the majority of central neurological disease (degenerative or vascular disease), which…
- Trial name
- TENSDEG (NCT01971320)
- Testing
- Urostim I stimulation
- Where
- 6 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Rouen
Cerebral Palsy (CP)
Scooter Board Activities on Neck Control and Dysphagia in Children With Cerebral Palsy
This study is a randomized control trial exploring the therapeutic effects of scooter board activities on neck control and dysphagia in children with cerebral palsy (CP).
- Trial name
- NCT06477224
- Testing
- Scooter Board Activities, Routine Physical Therapy
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Morbid Obesity, GERD
GERD After Sleeve Gastrectomy
The main adverse effect is gastroesophageal reflux disease (GERD), with concern on the development of Barrett's esophagus and esophageal adenocarcinoma in the long term. However, the relationship between SG and GERD is complex.
- Trial name
- NCT05178446
- Where
- Italy
- Volunteers
- 14,362 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Achalasia
Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia
Achalasia is a primary esophageal motility disorder where the lower esophageal sphincter fails to relax in response to swallowing with no well understood underlying cause.
- Trial name
- NCT01302288
- Testing
- Per oral endolumenal myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Oregon Clinic
Barrett's Esophagus, Radiofrequency Ablation
Radiofrequency Ablation in Patients With Barrett's Esophagus
The aim of this study is to establish a nationwide registry to collect data regarding the treatment of Barrett's Esophagus (BE) with radiofrequency ablation.
- Conditions
- Barrett's Esophagus, Radiofrequency Ablation, Gastroesophageal Reflux Disease
- Trial name
- RABE (NCT02793479)
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Matthias Paireder
Achalasia
Per-Oral Endoscopic Esophagomyotomy (POEM)
Achalasia is an esophageal motility disease that usually requires surgical intervention (esophagomyotomy). Laparoscopic techniques have reduced the morbidity associated with myotomy, but post-op GERD, wound infection, hernia and…
- Trial name
- POEM (NCT01635374)
- Testing
- Per-Oral Endoscopic Esophagomyotomy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Northwestern University
Stroke Sequelae, Deglutition Disorders
Effects of Different-Frequency Electroacupuncture on Suprahyoid Muscles in Post-Stroke Dysphagia: Efficacy and Neural Networks
This randomized controlled study in patients with post-stroke dysphagia aims to determine the optimal stimulation frequency of electroacupuncture of the suprahyoid muscles and to elucidate the underlying neural mechanisms.
- Conditions
- Stroke Sequelae, Deglutition Disorders, Acupuncture Therapy, Electroacupuncture
- Trial name
- NCT07496762
- Testing
- Low Frequency EA, Medium Frequency EA, High Frequency EA
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Kaili Chen
Ischemic Stroke, Hemiplegia
Combined Acupuncture-Based Therapy for Rehabilitation After Ischemic Stroke
Objective: To assess the therapeutic efficacy of combined electroacupuncture (or electric field acupuncture), hydroacupuncture (Cerebrolysin or B-complex vitamins), and acupressure massage in restoring motor function and treating…
- Conditions
- Ischemic Stroke, Hemiplegia, Neurogenic Dysphagia
- Trial name
- NCT07846488
- Testing
- Electro-Field Acupuncture, Electro-Acupuncture, Cerebrolysin
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- National Hospital of Acupuncture, Vietnam
Gastroesophageal Reflux Disease, Non Erosive Reflux Disease
Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)
The purpose of this study is to find out if people who have non-erosive reflux disease (NERD) have changes the investigators can see with a microscope (called confocal endomicroscopy) that is used during endoscopy (a camera scope…
- Conditions
- Gastroesophageal Reflux Disease, Non Erosive Reflux Disease, Dyspepsia
- Trial name
- CE_NERD (NCT02039869)
- Testing
- Confocal endomicroscopy, Proton pump inhibitor, Sucralfate
- Where
- 3 sites in United States
- Sponsor
- Virginia Commonwealth University
Reflux
Do Patients Who Have Had Surgery for Achalasia Suffer From Reflux
Patients who have had laparoscopic surgery for the treatment of achalasia will be asked to have pH studies done in order to determine is these patients suffer from reflux after surgery.
- Trial name
- NCT00519441
- Testing
- pH study
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kenneth Luberice
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