Clinical trials: Dehydration
Incisional Hernia
A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis
Currently, no standard of care exists to prevent incisional hernias (IH). This study will compare how frequently IH develop in standard abdominal closures vs. abdominal closures with dHACM added.
- Trial name
- NO-HERNIA (NCT04417140)
- Testing
- dHACM (AmnioWrap)
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Dehydration, Dehydration (Physiology)
Adequate Hydration and Health Outcomes
Cardiovascular diseases (CVD) are the leading cause of death in middle- and high-income countries, according to data from the World Health Organization (WHO).
- Conditions
- Dehydration, Dehydration (Physiology), Glucose Abnormalities, Cardiovascular
- Trial name
- HYDRATE (NCT07179107)
- Testing
- Baseline - week 1, Low Water Intake - week 2, Moderate Water Intake - week 3
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dehydration
Biomarkers for Noninvasive Assessment of Human Hydration
Low levels of dehydration (the loss of body water corresponding to 2% of the body weight), deteriorate physical and cognitive performance and may also be linked to a number of chronic diseases.
- Trial name
- NCT01507129
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gaia Medical Institute
Diarrhea, Infantile
IVC Index in Patient With Diarrhea and Dehydration And How It Affects Its Management
IVC Index in patient with Diarrhea and Dehydration And How It affects its management.
- Trial name
- NCT04654832
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dehydration in Children
Children Rehydration During Exercise
The low fluid intake in combination with a high intake of sugar-sweetened beverages (SSB) by children is a significant concern among public health professionals.
- Trial name
- ROAR (NCT06084702)
- Testing
- Rehydration with plain water, Rehydration Drink
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dehydration Hypertonic, Isotonic Dehydration
Effects of Dehydration on Neuromuscular Performance and Sympathetic Control of Cardiovascular Function
The mechanism(s) by which dehydration (both intra- and extracellular) impairs performance are still poorly described. A loss of volume results in increased occurrence of orthostatic intolerance, including dizziness, fatigue…
- Trial name
- NCT03263975
- Testing
- Gatorade or Enterade
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Dehydration, Mood
The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men
Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis…
- Trial name
- WEXMO (NCT05033665)
- Testing
- Increase water consumption, Maintain adequate water consumption
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dehydration
Non-Invasive Optical Spectroscopic Methods for Dehydration Identification in Marathon Trainees
Dehydration can result from exposure to harsh environments including hot and dry desert climates. Soldiers and non-military workers are frequently required to work in hot, dry conditions, and dehydration can be productivity…
- Trial name
- NCT01981902
- Testing
- Non-Invasive Optical Spectroscopic
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hypokalemia, Hyponatremia
Intravenous Fluids in Hospitalised Children
The main objective of the trial is to evaluate the risk of hypokalemia following administration of a isotonic solution compared to a hypotonic solution in acutely ill hospitalised children, who need intravenous fluid therapy.
- Conditions
- Hypokalemia, Hyponatremia, Hypernatremia, Dehydration
- Trial name
- NCT02926989
- Testing
- Plasmalyte Glucos 50 mg/mL, 0.45% saline in 5% dextrose
- Where
- Finland
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Dehydration
Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
The primary objective of this study is to analyze smart phone-based Transdermal Optical Imaging (TOI) features to develop a model that can discern hydration status, including: 1) at various timepoints throughout a 24-hour period…
- Trial name
- NCT06212518
- Testing
- GENPOP ad libitum fluid intake, GENPOP fluid restriction, ATHLETE ad libitum fluid intake
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Dehydration
Analysis of Sweat Secretion and Body Dehydration Monitoring
Monitoring of a person's physical status is a key point for maintaining of "healthy life". Wearable devices provide a unique possibility for real-time monitoring.
- Trial name
- NCT03229109
- Testing
- Spectrophon dehydration body monitor
- Where
- 2 sites in Israel
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Tirat Carmel Mental Health Center
Dehydration
Using Urine Color as a Marker of Hydration Status
The purpose of this study was to determine if rapid changes in hydration status could be determined by urine color expressed in CIE color space
- Trial name
- NCT05174793
- Testing
- dehydration and rehydration
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Insulin Resistance
The Effect of Vasopressin on Glucose Regulation
Data from experimental animals and human epidemiological studies have suggested that hypohydration and/or low water intake is linked to poor glucose regulation and diabetes.
- Trial name
- HYPERGlu (NCT02761434)
- Testing
- Hypertonic Saline (3% NaCl), Isotonic Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Malnutrition, Healthy Aging
Exploring the Feasibility of a Digital Service to Improve Nutrition and Hydration Status of Older Adults
Trial Design: This is a feasibility randomised controlled trial. Aim: The study aims to assess the feasibility of conducting a randomised controlled trial using a digital health tool (Keep-On-Keep-Up Nutrition, KOKU-Nut) to…
- Conditions
- Malnutrition, Healthy Aging, Dehydration
- Trial name
- NCT05943366
- Testing
- Keep-on-Keep-Up Nutrition (KOKU-Nut)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chloe French
Geriatric Population
Thirst for Knowledge
The purpose of this project is to determine the impact of hydration education on participant knowledge and water intake for residents in the independent living unit at Cornwall Manor.
- Trial name
- NCT07670767
- Testing
- Education with a regular hydration opportunity
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Dehydration, Heat Stress
Implementing an Intervention to Reduce Heat Stress and Chemical Exposures
The investigators are studying the dangers that farmworkers face while working in the fields and at home. The investigators goals are: 1. Measure how much heat and chemicals farmworkers in Imperial County are exposed to.
- Trial name
- NCT06442969
- Testing
- Education and resources provided by community health workers
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Evaluate the Fluorescence of Natural Tooth Following Dehydration
Effect of Dehydration on Dental Fluorescence
A cheek retractor will be placed to ensure consistent isolation throughout the procedure. Dehydration will be assessed at baseline, at the 5th minute, and at the 10th minute using three different evaluation techniques.
- Trial name
- NCT07295977
- Testing
- Digital photograph with Ashur plaque indicator, Digital photographs with the Led lights (365 nm), The QLF (Quantitative Light-Induced Fluorescence- 405 nm) images
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dehydration, Menstruation
Hydration & Female Life Stages
Female life stages including premenopausal, perimenopausal, postmenopausal, are characterized by changing concentrations and patterns of hormones.
- Conditions
- Dehydration, Menstruation, Pre-menopause, Peri-menopausal Women
- Trial name
- NCT07653620
- Testing
- electrolyte beverage
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Dehydration
Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase
The purpose is to evaluate the ease of use and technical challenges encountered during subcutaneous infusion of Lactated Ringer's (LR) solution, preceded by recombinant human hyaluronidase (hylenex), utilizing commonly used…
- Trial name
- INFUSE-AT (NCT00807885)
- Testing
- hylenex-facilitated subcutaneous Lactated Ringer's infusion
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Hot Weather; Adverse Effect, Kidney Dysfunction
Renal Considerations in the Heat Stress Recommendations
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is unknown, but may be related to kidney dysfunction caused by increases in body…
- Conditions
- Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia
- Trial name
- Aim1 (NCT04767347)
- Testing
- 23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Indiana University