Clinical trials: Delayed Development
Developmental Delay, Child Development
Validity and Reliability of Indonesian Translated Ages and Stages Questionnaires - Third Edition (ASQ-3) as a Screening Tool for Developmental Delay in 1-12 Months Old Children
This study aimed to provide the validity and reliability of the Indonesian ASQ-3 questionnaires as a screening tool for developmentally delayed children aged less than one year old. This study was divided into 2 phases.
- Conditions
- Developmental Delay, Child Development, Child Development Disorder, Global Developmental Delay
- Trial name
- NCT05398900
- Where
- Indonesia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Preterm, Extreme Prematurity
Effectiveness of Home Based Early Intervention of Extremely Premature Infant by Parent
This study is to prove the effectiveness of home based early intervention of extremely premature infant by Parent.
- Conditions
- Preterm, Extreme Prematurity, Early Intervention, Developmental Delay
- Trial name
- NCT05334550
- Testing
- Home Based Early Intervention by Parent
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center
Autism Spectrum Disorder
pBFS Guided rTMS Over Cognitive Control Network for ASD
The aim of this trial is to assess the efficacy and safety of precision neuromodulation for alleviating core symptoms in patients with autism spectrum disorder (ASD) who also have intellectual or developmental delay.
- Trial name
- NCT06255535
- Testing
- active iTBS treatment
- Where
- 6 sites in China
- Volunteers
- 215 people
- Sponsor
- Changping Laboratory
Cerebral Palsy, Spinal Muscular Atrophy
Pediatric Powered Wheelchair Standing Devices: An Exploratory Study
For children who use a power wheelchair, a powered wheelchair standing device (PWSD) may be considered for daily use. A PWSD allows a child to electronically move between sitting and standing and can be driven in either position.
- Conditions
- Cerebral Palsy, Spinal Muscular Atrophy, Spinal Cord Injuries, Spina Bifida
- Trial name
- NCT05117827
- Testing
- Power Wheelchair Standing Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Motor Delay
Effects of Conventional Physical Therapy With and Without Cuevas Medek Exercises in Developmental Delay
There are several etiologies for developmental delay (DD). One of the main causes of developmental delay is cerebral palsy (CP), which has a variety of clinical characteristics brought on by damage to the developing brain.
- Trial name
- NCT06522451
- Testing
- conventional physical therapy, Conventional physical therapy along with cuevas medek exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Prematurity, Extreme Prematurity
Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder
Extreme prematurity is constantly increasing according to the World Health Organization. However, methods to train premature infants at risk of disability is sorely lacking. The goal of this project is to overcome this problem.
- Conditions
- Prematurity, Extreme Prematurity, Infant Development, Brain Damage
- Trial name
- Premalocom2 (NCT06027645)
- Testing
- Crawling stimulation with a mini-skateboard (i.e. the crawliskate)
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Marianne Barbu-Roth
Intellectual Disability, Intellectual Disability, Mild
Therapeutic Play in Children With Mild Intellectual Disability
The aim of this study is to determine the effectiveness of a designed therapeutic play activities program on improving motor adaptive behavior in a sample of Egyptian children with mild intellectual disabilities.
- Conditions
- Intellectual Disability, Intellectual Disability, Mild, Motor and Developmental Delay, Motor Delay
- Trial name
- NCT06735482
- Testing
- Therapeutic play program
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Beni-Suef University
Down Syndrome, Gross Motor Delay
Up, Down, and All Around: Evaluating Mobility Devices for Young Children With Developmental Disabilities and Delays
This research study will examine young children with Down syndrome's initial experiences with mobility devices. Children's biomechanics and exploration will be quantified while they are using both an overground partial bodyweight…
- Conditions
- Down Syndrome, Gross Motor Delay, Cerebral Palsy
- Trial name
- NCT06591559
- Testing
- Permobil Explorer Mini, Portable Mobility Aid for Children (PUMA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder
Videoconferencing-based Focused Acceptance and Commitment Therapy for Parents of SHCN Children
The purpose of the proposed non-randomized waitlist-controlled design study is to evaluate the feasibility, acceptability, and potential effectiveness of using a Videoconferencing-based Individual Focused Acceptance and…
- Conditions
- Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Development Delay
- Trial name
- NCT05803252
- Testing
- Focused Acceptance and Commitment Therapy, Waitlist Control
- Where
- 5 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- Chinese University of Hong Kong
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pediatric Liver Transplantation, Developmental Delay
Intraoperative Cerebral and Renal Tissue Oxygen Saturation and Pediatric Living Donor Liver Transplantation Prognosis.
This rSO2 study is a prospective clinical study. The purpose of the rSO2 study is to investigate whether there is a correlation between the intraoperative cerebral and renal tissue oxygen saturation and the incidence of…
- Conditions
- Pediatric Liver Transplantation, Developmental Delay, Postoperative Complications, Socioemotional Delay
- Trial name
- rSO2-LDLT (NCT04518332)
- Where
- China
- Volunteers
- 123 people
- Sponsor
- RenJi Hospital
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Language Development, Language Delay
A Language Intervention Study of Preterm Infants
This is a randomized controlled trial to study a reading intervention in the NICU among preterm infants using LENA (Language Environment Analysis) recordings, linguistic feedback, and a language curriculum to improve the neonatal…
- Conditions
- Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
- Trial name
- NCT03688386
- Testing
- Reading intervention, Infant bonding, LENA recording
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Neonatal Encephalopathy, Therapeutic Hypothermia
The Long-term Consequences of Neonatal Encephalopathy in the Hypothermia Era
The goal of this study is to characterize the ability and related brain profiles of children with Neonatal encephalopathy (NE) - Therapeutic hypothermia (TH) at 9 years old. The main questions it aims to answer are: 1.
- Conditions
- Neonatal Encephalopathy, Therapeutic Hypothermia, Brain Injuries, Child Development
- Trial name
- NCT05756296
- Testing
- Therapeutic hypothermia
- Where
- 2 sites in Canada
- Volunteers
- 198 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Language Delay, Developmental Language Disorders
Effectiveness of Early Parent-Based Language Intervention
The purpose of the study is to examine the effectiveness of a highly-structured parent-based language intervention group program for two-year-old children with language delay.
- Trial name
- NCT00625261
- Testing
- Heidelberg Parent-based Language Intervention HPLI
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
Infertility, Abortion, Spontaneous
Development of a Bioabsorbable Medical Device for the Prevention of Postoperative Intra-uterine Adhesions.
The main objective of this study is to describe the level of expression of the biological factors involved in the formation of adhesions (Transforming growth factor beta, Activin A, inhibin) at the time of a first diagnostic…
- Conditions
- Infertility, Abortion, Spontaneous, Embryo Implantation, Delayed
- Trial name
- PréSynUT-1 (NCT02328742)
- Testing
- Hysteroscopy + endometrial biopsy, Telephone call, Resection + endometrial biopsy
- Where
- 3 sites in France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Autism Spectrum Disorder, Social Communication Disorder
Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
The goal of this randomized control trial is to test the efficacy of the Social ABCs 6 week, group-based model using a virtual delivery platform.
- Conditions
- Autism Spectrum Disorder, Social Communication Disorder, Autism or Autistic Traits, Autism Spectrum Disorder With Impaired Functional Language
- Trial name
- NCT05663970
- Testing
- VG Social ABCs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital