Clinical trials: Delayed Onset Muscle Soreness (DOMS)
Hypermobility Syndrome
The Effect of Joint Hypermobility Syndrome on Delayed Onset of Muscle Soreness and Recovery Time
The purpose of the study is to investigate Joint Hypermobility Syndrome (JHS) and its effect on delayed onset muscle soreness (DOMS) and recovery time.
- Trial name
- NCT04934267
- Testing
- Eccentric Exercise for subjects with JHS, Eccentric Exercise for Controls
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Injury;Sports
Post-exercise Recovery of DOMS in Recreational Athletes
The main goal of this study was to investigate the effectiveness of cryo-sauna in preventing the development of DOMS in the lower extremity.
- Trial name
- NCT05757518
- Testing
- Cryosauna
- Where
- Poland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Delayed Onset Muscle Soreness (DOMS)
PNF Versus Cryotherapy in Delayed Onset Muscle Soreness
This randomized, double-blind, single-center pilot clinical trial evaluated three interventions for delayed onset muscle soreness in the hamstring muscles. Twenty-nine untrained adults were included.
- Trial name
- NCT07624032
- Testing
- Proprioceptive Neuromuscular Facilitation, Local Cryotherapy
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia de Salamanca
Myalgia
Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS)
The potential benefits of exercise for the treatment of chronic inflammatory diseases and pain have been well documented in the scientific literature.
- Trial name
- UEL (NCT06125002)
- Testing
- Diosmin750
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sergio Marques Borghi
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Delayed Onset Muscle Soreness (DOMS)
Effects of Sports Massage and Thai Massage on Delayed-Onset Muscle Soreness and Recovery
This study investigated the effects of sports massage and modified traditional Thai massage on delayed-onset muscle soreness (DOMS) and recovery following strenuous exercise in healthy, physically inactive young men.
- Trial name
- NCT07892118
- Testing
- Sports Massage, Traditional Thai Massage, Passive Recovery
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS), Muscle Damage, Photobiomodulation (PBM)
- Trial name
- NCT07790016
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Acute Delayed Onset Muscle Soreness (DOMS)
Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness
This study evaluate the efficacy and safety of Etodolac-lidocaine topical patch applied one time daily when compared with placebo in the treatment of acute Delayed Onset Muscle Soreness (DOMS) of the upper limbs.
- Trial name
- NCT02695381
- Testing
- Etodolac-lidocaine topical patch
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MEDRx USA, Inc.
Delayed Onset Muscle Soreness (DOMS)
The Effect of Percussion Massage Therapy on the Recovery of DOMS in Physically Active Young Men Delayed Onset Muscle Soreness = DOMS
The goal of this clinical trial is to learn the effect of percussion massage therapy (PMT) on the recovery of delayed onset muscle soreness (DOMS) in physically active young men.
- Trial name
- Required (NCT06612502)
- Testing
- Static stretching, Fascia gun ( Short-time PMT ), Fascia gun ( Long-time PMT )
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanxi Normal University
Electromagnetic Fields
Effect of Pulsed Electromagnetic Stimulation on DOMS
The aim of our study is to investigate the effect of Pulsed Electro Magnetic Field application on delayed muscle soreness in healthy Quadriceps femoris muscle.
- Trial name
- NCT05554874
- Testing
- Pulsed electromagnetic fields
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Pain, Delayed Onset Muscle Soreness
An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
The purpose of this study is to evaluate analgesic efficacy of Topical Voltaren Gel (diclofenac sodium gel) 1% applied QID compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness.
- Trial name
- NCT02087748
- Testing
- 1% diclofenac sodium gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Delayed Onset Muscle Soreness
Pilot Study Comparing the Efficacy and Safety of a New Pain Patch and Placebo in Delayed Onset Muscle Soreness (DOMS)
The purpose of this study is to evaluate the analgesic efficacy and safety of a new pain patch compared to placebo and no treatment in subjects experiencing Delayed Onset Muscle Soreness (DOMS).
- Trial name
- NCT02602353
- Testing
- Loxoprofen Pain Patch, No Treatment
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lead Chemical Co., Ltd.
Delayed Onset Muscle Soreness (DOMS)
Vibrating and Non-Vibrating Foam-Rolling on DOMS
The goal of this randomized clinical trial is to determine whether vibrating foam rolling is more effective than non-vibrating foam rolling for improving ankle function and reducing muscle soreness after delayed onset muscle…
- Trial name
- NCT07877181
- Testing
- Vibrating Foam Rolling, Non-Vibrating Foam Rolling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Delayed Onset Muscle Soreness
Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness
This is a Phase 2, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the dosing interval, efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24…
- Trial name
- DIS DOMS (NCT02339129)
- Testing
- SST-0225
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage
TENS Versus Foam Rolling for Muscle Recovery After Eccentric Exercise in Elite Female Volleyball Players
Purpose: This study compared two recovery methods-transcutaneous electrical nerve stimulation (TENS) and foam rolling (FR)-for muscle recovery after intense exercise in elite female volleyball players.
- Conditions
- Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage, Muscle Recovery, Athletic Injuries
- Trial name
- TENS-FR-VB (NCT07438197)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Foam Rolling (FR)
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage
Antioxidant Supplementation and Muscle Recovery From DOMS in Trained Women
This randomized, placebo-controlled, parallel-group trial investigated the effects of combined antioxidant and anti-inflammatory supplementation on delayed onset muscle soreness (DOMS) recovery in trained women.
- Conditions
- Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage, Muscle Recovery
- Trial name
- NCT07877441
- Testing
- Creatine Monohydrate, Omega 3 FA (Fish Oil), N-Acetyl Cysteine (NAC)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez