Clinical trials: Delayed-onset Muscle Soreness
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Myalgia [C05.651.542]
Cryotherapy and Laser Therapy on Muscle Damage
This study propose investigate the effect of cryotherapy and laser therapy in response to strenuous exercise-induced muscle damage on the biceps brachii muscle (muscle of the arms).
- Trial name
- CLMD (NCT02327988)
- Testing
- Cryotherapy, Laser therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Hypermobility Syndrome
The Effect of Joint Hypermobility Syndrome on Delayed Onset of Muscle Soreness and Recovery Time
The purpose of the study is to investigate Joint Hypermobility Syndrome (JHS) and its effect on delayed onset muscle soreness (DOMS) and recovery time.
- Trial name
- NCT04934267
- Testing
- Eccentric Exercise for subjects with JHS, Eccentric Exercise for Controls
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Injury;Sports
Post-exercise Recovery of DOMS in Recreational Athletes
The main goal of this study was to investigate the effectiveness of cryo-sauna in preventing the development of DOMS in the lower extremity.
- Trial name
- NCT05757518
- Testing
- Cryosauna
- Where
- Poland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Delayed Onset Muscle Soreness (DOMS)
PNF Versus Cryotherapy in Delayed Onset Muscle Soreness
This randomized, double-blind, single-center pilot clinical trial evaluated three interventions for delayed onset muscle soreness in the hamstring muscles. Twenty-nine untrained adults were included.
- Trial name
- NCT07624032
- Testing
- Proprioceptive Neuromuscular Facilitation, Local Cryotherapy
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia de Salamanca
Delayed Onset Muscle Soreness
Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery
Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS).
- Trial name
- NCT06815367
- Testing
- Pneumatic Compression, Blood Flow Restriction
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Myalgia
Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS)
The potential benefits of exercise for the treatment of chronic inflammatory diseases and pain have been well documented in the scientific literature.
- Trial name
- UEL (NCT06125002)
- Testing
- Diosmin750
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sergio Marques Borghi
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Delayed Onset Muscle Soreness (DOMS)
Effects of Sports Massage and Thai Massage on Delayed-Onset Muscle Soreness and Recovery
This study investigated the effects of sports massage and modified traditional Thai massage on delayed-onset muscle soreness (DOMS) and recovery following strenuous exercise in healthy, physically inactive young men.
- Trial name
- NCT07892118
- Testing
- Sports Massage, Traditional Thai Massage, Passive Recovery
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS), Muscle Damage, Photobiomodulation (PBM)
- Trial name
- NCT07790016
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Acute Delayed Onset Muscle Soreness (DOMS)
Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness
This study evaluate the efficacy and safety of Etodolac-lidocaine topical patch applied one time daily when compared with placebo in the treatment of acute Delayed Onset Muscle Soreness (DOMS) of the upper limbs.
- Trial name
- NCT02695381
- Testing
- Etodolac-lidocaine topical patch
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MEDRx USA, Inc.
Delayed Onset Muscle Soreness (DOMS)
The Effect of Percussion Massage Therapy on the Recovery of DOMS in Physically Active Young Men Delayed Onset Muscle Soreness = DOMS
The goal of this clinical trial is to learn the effect of percussion massage therapy (PMT) on the recovery of delayed onset muscle soreness (DOMS) in physically active young men.
- Trial name
- Required (NCT06612502)
- Testing
- Static stretching, Fascia gun ( Short-time PMT ), Fascia gun ( Long-time PMT )
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanxi Normal University
Electromagnetic Fields
Effect of Pulsed Electromagnetic Stimulation on DOMS
The aim of our study is to investigate the effect of Pulsed Electro Magnetic Field application on delayed muscle soreness in healthy Quadriceps femoris muscle.
- Trial name
- NCT05554874
- Testing
- Pulsed electromagnetic fields
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Pain, Delayed Onset Muscle Soreness
An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
The purpose of this study is to evaluate analgesic efficacy of Topical Voltaren Gel (diclofenac sodium gel) 1% applied QID compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness.
- Trial name
- NCT02087748
- Testing
- 1% diclofenac sodium gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Pain
Topical Ibuprofen for Delayed Onset Mulscle Soreness
The objective of this study is to compare the efficacy and safety of Ibuprofen 5% Topical Gel versus placebo administered two or three times daily for the treatment of pain associated with delayed onset muscle soreness following…
- Trial name
- NCT01794923
- Testing
- IBU BID, IBU TID
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Pfizer
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis