Clinical trials: Delayed-onset Muscle Soreness
Delayed Onset Muscle Soreness, DOMS
Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness (DOMS)
This is a Phase 3, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24 hours, over a…
- Trial name
- DOMS (NCT02597634)
- Testing
- SST-0225
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Delayed Onset Muscle Soreness
Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
Numerous techniques are reported to enhance recovery following intense exercise, however there is equivocal support for such claims.
- Trial name
- NCT02018211
- Testing
- control, graduated compression socks, neuromuscular electrical stimulation device
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Firstkind Ltd
Phototherapy
Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes
Therapy with light emitting diodes (LED) is a good resource to accelerate the recovery of the athlete and reduce muscle damage caused by exercise.
- Trial name
- NCT03728439
- Testing
- LED before, LED interval, LED after
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Delayed Onset Muscle Soreness
Effects of a Polyherbal Supplement on the Signs and Symptoms of Delayed Onset Muscle Soreness
This study is a randomized, double-blind, placebo-controlled, crossover design study in healthy subjects to determine the effects of a polyherbal supplement on the signs and symptoms of delayed onset muscle soreness (DOMS)…
- Trial name
- NCT02157675
- Testing
- Polyherbal capsule
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NewChapter, Inc.
Delayed Onset Muscle Soreness Experimentally Induced
Clinical and MRI Characteristics of Delayed Onset Muscle Soreness (DOMS) of the Shoulder Rotator Muscles Induced by Eccentric Exercise: An Exploratory Prospective Experimental Study
The purpose of this study is to characterize the clinical and radiological manifestations of delayed onset muscle soreness (DOMS) experimentally induced by an isokinetic eccentric contraction protocol targeting the shoulder…
- Trial name
- DOMEX (NCT07880782)
- Testing
- Isokinetic dynamometer
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Musculoskeletal Pain, Healthy
Multivariable Recovery After Exercise-induced Muscle Pain in the Forearm Muscles
This study investigates the evolution of sensory, motor and tissue variables following exercise-induced pain in wrist extensor muscles in healthy subjects.
- Conditions
- Musculoskeletal Pain, Healthy, Delayed Onset Muscle Soreness
- Trial name
- NCT04012203
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Delayed-Onset Muscle Soreness
Effects of Kinesio Taping on Delayed-Onset Muscle Soreness and Functional Recovery
This study evaluates the effects of kinesio taping applied to the quadriceps femoris on delayed-onset muscle soreness, lower-extremity range of motion, and explosive jump performance following a fatiguing exercise protocol in…
- Trial name
- NCT07840690
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Firat University
Muscle Soreness
Topical Eucalyptus Globulus and Mentha x Piperita on Muscle Soreness in Older Adults and the Elderly
Subjects over age 50 with no previous resistance training sessions will be recruited at a subacute rehabilitation and long term care facility.
- Trial name
- NCT04866407
- Testing
- Mentha x piperita, Eucalyptus globulus
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain
Mirthful Laughter and Muscle Soreness / Pain
The purpose of this study is first to investigate the effect of a controlled intervention with a comedy video on pain tolerance in a social setting while quantitatively measuring laughter in a young healthy population…
- Trial name
- NCT02896075
- Testing
- 30 Minute Comedy Video, 30 Minute Documentary Video
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy
Effects Of Yoga Before vs After Eccentric Exercise On Delayed Onset Muscle Soreness
The goal of this clinical trial is to compare the effects of pre and post-exercise yoga after eccentric exercise on delayed onset muscle soreness in healthy adults.
- Trial name
- NCT05854771
- Testing
- Single bout of yoga before eccentric exercise, Single bout of yoga after eccentric exercise
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Muscle Soreness
Ibuprofen Versus Placebo For Muscle Soreness
The study will assess the sensitivity of the Delayed Onset Muscle Soreness Model by comparing the safety and efficacy of oral ibuprofen to placebo over 24 hours.
- Trial name
- NCT03228992
- Testing
- Ibuprofen 400 mg
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Jean Brown Research
Delayed Onset Muscle Soreness
Effects of Allicin Pretreatment on Anti-oxidation Ability and Delayed Onset Muscle Soreness
To investigate the effects of allicin pretreatment on delayed onset muscle soreness (DOMS), muscle function, and oxidative stress following eccentric exercise
- Trial name
- NCT07812688
- Testing
- allicin
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guangxi Normal University
Musculoskeletal Pain, Soreness, Muscle
Effects of Instrument Assisted Soft Tissue Mobilization on Delayed Onset Muscle Soreness
The aim of our study is to investigate the effect of instrument assisted soft tissue mobilization therapy on delayed onset muscle soreness
- Conditions
- Musculoskeletal Pain, Soreness, Muscle, Musculoskeletal Disorder
- Trial name
- NCT05531851
- Testing
- Instrument Assisted Soft Tissue Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Muscles
Rates of Recovery From Strenuous Exercise in Physically Active Older Adults
The purpose of this study to determine if older adults who are healthy and physically active (i.e., Masters athletes) demonstrate slower rates of recovery from unaccustomed strenuous exercise of downhill running than younger…
- Trial name
- NCT02899650
- Testing
- exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Recovery, Psychological, Transcranial Magnetic Stimulation
Evaluating Combined Electromagnetic Stimulation for Enhanced Physical and Psychological Recovery in Athletes with DOMS
This randomized controlled trial explores the impact of a combined transcranial and peripheral electromagnetic stimulation over the potential correlation between psychological well-being and recovery outcomes of young athletes…
- Trial name
- NCT06855316
- Testing
- electromagnetic stimulation
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Delayed Onset Muscle Soreness
Effects of Percussive Massage Treatment With Theragun on Post Exercise Delayed Onset Muscle Soreness
This project will be Randomized control trial conducted to check the effects of percussive massage treatment with theragun on pain and muscle length on post exercise delayed onset muscle soreness (DOMS) of calf muscles in healthy…
- Trial name
- NCT05026944
- Testing
- Percussive massage and static stretching exercises, static stretching exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Acute Pain
A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity
The purpose of this study to evaluate the efficacy and safety of K-285 compared with menthol gel for the treatment of delayed onset muscle soreness (DOMS) in the lower extremity.
- Trial name
- NCT04484428
- Testing
- K-285, Menthol
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.