Clinical trials: Dementia; Degenerative, Dementia Mixed
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Dementia, Dementia, Vascular
Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept Study
Due to COVID-19, the routine treatment for dementia, Cognitive Stimulation Therapy (CST), is currently suspended in multiple countries. Access to treatment is, therefore, paramount.
- Conditions
- Dementia, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies
- Trial name
- V-iCST (NCT04828434)
- Testing
- Virtual Individual Cognitive Simulation Therapy
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University College, London
Alzheimer's Disease, Dementia
Blood Gene Expression Signature in Patients Diagnosed With Probable Alzheimer's Disease Compared to Patients Suffering From Other Types of Dementia
The objective of the study is to define the performance of blood-based signatures for Alzheimer's Disease (AD) in different patients populations including AD, non-AD dementia, and non-demented controls.
- Trial name
- NCT00880347
- Testing
- Blood sampling
- Where
- 21 sites in France
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Exonhit
Dementia, Mild Cognitive Impairment
SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia
Assistive Technologies (ATs) can help people living with dementia (PwD) maintain their everyday activity. Still, there is a gap between potential and supply. Involving future users can close the gap.
- Conditions
- Dementia, Mild Cognitive Impairment, Alzheimer Disease, Dementia With Lewy Bodies
- Trial name
- SAIN_UMR (NCT05885620)
- Testing
- drinking reminder and cognitive task (smartwatch-based application)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Rostock
Dementia, Dementia, Vascular
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members.
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease
- Trial name
- PICSI-M (NCT05596760)
- Testing
- Jumpstart Guide
- Where
- 3 sites in United States
- Volunteers
- 1,802 people
- Sponsor
- University of Washington
Dementia, Dysphagia
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia.
- Conditions
- Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular
- Trial name
- NCT06471660
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Depression, Stress, Psychological
Rural Dementia Caregiver Project
Rural caregivers face challenges of geographic isolation and lower health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their…
- Conditions
- Depression, Stress, Psychological, Self Efficacy, Loneliness
- Trial name
- NCT04428112
- Testing
- Building Better Caregivers Workshop, Attention Control
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dementia, Mixed, Dementia, Vascular
Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy
The STAREE-Mind imaging sub-study will examine the effect of statin treatment over a 4-year period, compared with placebo, on markers of brain health.
- Conditions
- Dementia, Mixed, Dementia, Vascular, Dementia of Alzheimer Type, Cognitive Decline
- Trial name
- STAREE-Mind (NCT05586750)
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- 2 sites in Australia
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Monash University
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dementia, Mild Cognitive Impairment (MCI)
Comprehensive Assessment of Neurodegeneration and Dementia
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits.
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Subjective Cognitive Impairment, Parkinson's Disease (PD)
- Trial name
- COMPASS-ND (NCT03402919)
- Where
- 19 sites in Canada
- Volunteers
- 1,573 people, healthy volunteers welcome
- Sponsor
- McGill University
Alzheimer Disease, Frontotemporal Degeneration (FTD)
PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia
Caregivers of individuals with Alzheimer's disease and related dementia rarely get the preparation or training they need to manage their caregiving responsibilities and to successfully balance their own self-care and their…
- Conditions
- Alzheimer Disease, Frontotemporal Degeneration (FTD), Lewy Body Dementia (LBD), Vascular Contributions to Cognitive Impairment and Dementia (VCID)
- Trial name
- NCT04748666
- Testing
- Problem Solving Training
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dementia; Degenerative, Dementia Mixed
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday).
- Trial name
- tES (NCT06877312)
- Testing
- Transcranial Direct Current Stimulation (tDCS), 30 Hz Transcranial Alternating Current Stimulation (tACS), 50 Hz Transcranial Alternating Current Stimulation (tACS)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Dementia of Alzheimer Type, Alzheimer Disease
Telehealth-enabled Integrated Palliative Care for People With Dementia
In prior work, this team developed a telehealth primary care model (TIPC), designed in close partnership with patients and clinicians to address a widespread increase in telehealth use during the COVID-19 pandemic.
- Conditions
- Dementia of Alzheimer Type, Alzheimer Disease, Frontotemporal Degeneration, Lewy Body Dementia
- Trial name
- IBC (NCT05524181)
- Testing
- Telehealth Integrated Primary Care (TIPC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Dementia, Alzheimer Disease
Feasibility of Passive Data Collection in Dementia Subjects With Agitation
This is a multi-center, observational, feasibility study, to evaluate long term passive data collection, data quality, and user experience of HealthMode Agitation (Apps) to collect motion, location, physiological, and audio data…
- Conditions
- Dementia, Alzheimer Disease, Vascular Dementia, Frontotemporal Dementia
- Trial name
- NCT04413851
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- HealthMode Inc.