Clinical trials: Dental Developmental Disorders and Anomalies
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Pit and Fissure Sealants, Molar Incisor Hypomineralization
Clinical Evaluation of Two Different Pit and Fissure Sealants
It is planned to include girls and boys between the ages of 6-12 who apply to Başkent University Faculty of Dentistry, Pediatric Dentistry Clinic for routine dental examination.
- Trial name
- NCT06776471
- Testing
- Resin-based flowable filling material
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Baskent University
Molar Incisor Hypomineralization
Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization
To compare responses to electrical pulp test (EPT) and cold test among molar incisor hypomineralization (MIH)-effected and not MIH-effected carious teeth before and after administration of local anesthesia for caries removal.
- Trial name
- NCT04061096
- Testing
- Evaluation of cold test, Evaluation of electrical pulp test, Evaluation of pain during the treatment
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Molar Incisor Hypomineralization
Prevalence And Severity Of Molar Incisor Hypomineralization Among A Group Of Children With Type I Diabetes Milletus.
Determine the prevalence of molar incisor hypomineralization among a group of children with type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes .
- Trial name
- NCT06342089
- Testing
- Type I diabetes milletus
- Volunteers
- 238 people
- Sponsor
- Cairo University
Hypomineralization of Enamel
Esthetic Management of Anterior Teeth Utilizing Two Micro Abrasion Treatments
the aim of this clinical trial is to compare the new micro-abrasion material "ANTIVET" compared to the conventional micro-abrasion material used widely "opalustre".
- Trial name
- NCT05900817
- Testing
- antivet, Oplsture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Enamel Hypoplasia
Injection Molding Technique: A Minimally Invasive Management for Enamel Hypoplasia Affecting Permanent Anterior Teeth in Children
This study aims to evaluate and compare the clinical performance of the injectable giomer restoration versus an injectable composite resin restoration using the injection molding technique for veneering hypoplastic permanent…
- Trial name
- NCT06205420
- Testing
- Injectable composite resin restoration, Injectable giomer restoration, Active comparator: Direct composite resin laminate
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypomineralization of Enamel, Hypomineralization Molar Incisor
The Association Between MIH and HSPM
Aim of the Study Evaluate association between HSPM and MIH in Egyptian children. Record the prevalence of HSPM and MIH in Egyptian children
- Trial name
- NCT04344340
- Testing
- clinical examination
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Evaluation of the Effectiveness of Various Desensitizing Treatment Protocols
The objective of this research was to evaluate the clinical success of desensitization treatments using four different materials in the first permanent molars (FPMs) affected by MIH.
- Trial name
- NCT07085689
- Testing
- Sodium Fluoride Varnish (5%), Silver diamine fluoride- potassium iodide, Aqueous Silver Fluoride
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hacettepe University
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Molar Incisor Hypomineralization
Effect of Low-intensity Laser and Photodynamic Therapy on Infected Dentin of Permanent Teeth With MIH
The objective of this research was to evaluate the clinical effect of photodynamic therapy on dentin infected by caries lesion in permanent teeth with Molar Incisor Hypomineralization (MIH).
- Trial name
- NCT03826810
- Testing
- aPDT, ART
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Giza Governorate
One single operator will assess the prevalence of molar incisor hypomineralization and its Severity among a group of Egyptian children .
- Trial name
- MIH (NCT03233464)
- Where
- Egypt
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralisation
Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization
Molar Incisor Hypomineralization (MIH) is a common developmental enamel defect affecting children, particularly in Dubai, where it contributes to hypersensitivity, esthetic concerns, plaque accumulation, and increased caries…
- Trial name
- MIH-CARE (NCT07177053)
- Testing
- non fluoridated hydroxyapatite tooth paste (KAREX KINDER tooth paste), fluoridated toothpaste (Colgate Total PROTECTION ACTIVE)
- Volunteers
- 160 people
- Sponsor
- Dubai Health
Dental Caries, Tooth Hypomineralization
Zirconia and Bioflx Crowns for Primary Anterior Teeth
This parallel-group randomized controlled trial will compare the clinical performance of prefabricated zirconia and Bioflx crowns for restoring primary maxillary anterior teeth in children aged 3 to 5 years.
- Trial name
- NCT07691905
- Testing
- Zirconia Crown, Bioflx Crown
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- Hue University of Medicine and Pharmacy
Molar Incisor Hypomineralization
Educational Program to Improve Dental Interns, Knowledge ,Attitude and Awareness Toward Molar Incisor Hypo-mineralization.
This interventional, quasi experimental study aims to assess the effectiveness of an educational program on improving dental interns' knowledge, attitude and awareness regarding Molar-Incisor Hypo-mineralization (MIH).
- Trial name
- MIH (NCT07129720)
- Testing
- Educational Program on MIH
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Molar Incisor Hypomineralization
Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH
This trial will compare the application of Glass Ionomer Cement (GIC) sealant with no-intervention for the most clinically- and cost-effective strategy for managing MIH molars without post-eruptive breakdown, in a school setting…
- Trial name
- MIHMex (NCT03870958)
- Testing
- GIC sealant (GC Fuji TRIAGE®), Control
- Where
- Mexico
- Volunteers
- 195 people
- Sponsor
- Isabel Cristina Olegário da Costa
Molar Incisor Hypomineralization
Association Between Molar-Incisor Hypomineralization, Maternal Stress and Anxiety: A Cross-Sectional Study.
This study aims to evaluate the association between Molar-Incisor Hypomineralization, Maternal Stress and anxiety in a group of pediatric patients.
- Trial name
- NCT06081491
- Testing
- diagnosis
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar-Incisor Hypomineralization, Peridontal Disease
Molar-Incisor Hypomineralization Vs Periodontal Health
Background: To investigate the effect of molar incisor hypomineralization (MIH) on periodontal health, to evaluate the relationship between gingival crevicular fluid (GCF) volume, and GCF biomarkers such as matrix…
- Trial name
- MIH (NCT06764043)
- Testing
- Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge