Clinical trials: Dental Implant, open to volunteers
Alveolar Bone Loss, Edentulism Nos
The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation
Pneumatization of the maxillary sinus may lead to insufficient bone volume for dental implant placement in the edentulous posterior maxilla.
- Trial name
- NCT06533397
- Testing
- Sinus floor elevation (SFE), preoperative cone beam computed tomography (CBCT), postoperative CBCT
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Socket Shield Technique, Concentrated Growth Factors
Immediate Implant Placement Using Socket Shield With CGF
This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic…
- Conditions
- Socket Shield Technique, Concentrated Growth Factors, Immediate Dental Implant Placement, Alveolar Bone Preservation
- Trial name
- CGF (NCT07520526)
- Testing
- Immediate implant placement with Socket Shield Technique and CGF
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Peri Implant Mucositis, Peri Implantitis
Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages.
- Trial name
- AmbiJet-FIH (NCT07722715)
- Testing
- AmbiJet cold plasma system, Standard Mechanical Debridement (S3 Guideline)
- Where
- Ukraine
- Volunteers
- 26 people
- Sponsor
- Freiburger Medizintechnik GmbH
Dental Implant, Bone Grafting
Influence of Alveolar Bone Drilling and Anatomical Position on Integration
The goal of this clinical trial is to learn if alveolar bone drilling and anatomical position of an immediately placed dental implant has influence on the primary stability, osseointegration and function.
- Conditions
- Dental Implant, Bone Grafting, Immediate Dental Implant Placement
- Trial name
- NCT07589140
- Testing
- dental implant placement, Dental implant
- Where
- Lithuania
- Volunteers
- 124 people
- Sponsor
- Lithuanian University of Health Sciences
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge
Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.
The purpose of the study is to compare soft tissue volume changes in terms of volume gain and stability around dental implants and PROMS in cases where a sub-epithelial connective tissue graft (SCTG) from the palate, Porcine…
- Conditions
- Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge, Edentulous Alveolar Ridge
- Trial name
- NCT04766255
- Testing
- Soft Tissue graft augmentation, Implant Placement
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Failure, Prosthesis, Dental Prosthesis, Implant-Supported
Clinical Performance of All-on-4 PEEK and Conventional Prostheses
The all-on-4 treatment approach for completely edentulous mandible is a proven concept. However, there are still issues regarding the use of metal substructure to support the prostheses such as allergy, metallic taste, and…
- Conditions
- Failure, Prosthesis, Dental Prosthesis, Implant-Supported, Survival, Prosthesis, Complete Edentulism
- Trial name
- NCT06388395
- Testing
- Accuracy of full-arch surgical guides, Survival and complications of the prostheses, Survival and complications of the implants
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Dental Implant
Mucograft Seal in ARP Follow-up
Rationale: Early implant placement with alveolar ridge preservation (ARP) using either a collagen matrix or a palatal graft rendered similar esthetic, clinical and PROMs to early implant placement without ARP, up to 1 year after…
- Trial name
- NCT05663385
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Erasmus Medical Center
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Keratinized Mucosa Deficiency, Peri-implant Soft Tissue
Apical Flap Repositioning vs. Mucosa Excision With Free Gingival Grafts for Peri-Implant Keratinized Mucosa Augmentation
The goal of this clinical trial is to learn which surgical technique works better to increase the amount of firm gum tissue (called keratinized mucosa) around dental implants in adults.
- Conditions
- Keratinized Mucosa Deficiency, Peri-implant Soft Tissue, Dental Implants
- Trial name
- FGGIF (NCT07772414)
- Testing
- Free gingival graft with apical flap repositioning, Free gingival graft with vestibular mucosa excision
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Dental Implant, Immediate Dental Implant Placement
Melatonin Effect on Immediate Dental Implants in the Posterior Mandible
This pilot randomized controlled clinical trial aims to evaluate the feasibility, clinical safety, and preliminary radiographic osteogenic effects of applying topical 1% w/w melatonin gel during immediate implant placement in the…
- Conditions
- Dental Implant, Immediate Dental Implant Placement, Alveolar Bone Loss, Bone Density
- Trial name
- NCT07869030
- Testing
- 1% w/w Melatonin Gel, Standard Immediate Dental Implant Placement
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Future University in Egypt
Implant Site Reaction
Photofunctionalization With UVC
Summary: Objective: The general objective is to compare the placement of standard implants with a surface photofunctionalization technique based on ultraviolet C radiation (UVC), having as working hypothesis that this…
- Trial name
- EPID (NCT06724107)
- Testing
- UVC
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Implant
Effect of Povidone Iodine on the Dental Implant Internal Surface Microbiome
We hope to learn if applying antiseptic to the inside of a dental implant will decrease or alter the types of bacteria inside it which may then decrease the incidence of implant failure associated with bone loss, infection, and…
- Trial name
- NCT07899983
- Testing
- Povidone-Iodine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Madigan Army Medical Center
Dental Implant, Edentulous Alveolar Ridge
Clinical and Radiographic Comparison of Two Implant-Abutment Connections
The aim of this clinical study is to evaluate two different implant-abutment connection design on preserves gingiva and bone health in the long term.
- Trial name
- NCT07889882
- Testing
- N1 Dental implant placement + N1 abutment, Nobel active Implant placement + on1 abutment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kutahya Health Sciences University
Partially Edentulous Mandible
Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Guided Implant Placement
The AI assisted CAD/CAM workflow will be adopted for the treatment planning and guide design generation with the aim of comparing precision of implant placement with conventional digital workflow.
- Trial name
- Implant (NCT07523815)
- Testing
- AI assisted implant placement, Conventional computer guided implant placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sandra Moussa Botros El Tarzi
Complete Edentulism
Microbial Adhesion and Peri-Implant Tissue Health in All-on-Four Hybrid Prostheses Supported by Zantex or Zirconia Frameworks
This study compares two materials (Zantex and Zirconia) used to make fixed full-arch dental prostheses supported by four dental implants (the "All-on-Four" technique) in patients who have no natural teeth in the lower jaw.
- Trial name
- NCT07811661
- Testing
- Zirconia Framework, Zantex Framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Kafrelsheikh University
Dental Implants, Dental Prosthesis, Implant-Supported
Clinical Evaluation of a Hyperbolic Paraboloid Triple-Abutment on Morse Taper Dental Implants
This prospective clinical study aims to evaluate the clinical and radiographic outcomes of a novel triple-abutment system with hyperbolic paraboloid geometry installed on Morse taper dental implants.
- Trial name
- NCT07310979
- Testing
- Triple-Abutment System with Hyperbolic Paraboloid Geometry
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania