Clinical trials: Dental Occlusion
Ischemic Heart Disease, Coronary Atherosclerosis
T-provisional Stenting vs Mini-Crush in Chronic Total Occlusions (CTO)
The aim is to compare the results of using T-provisional and Mini-Crush stenting techniques in patients with bifurcation lesions in the CTO segment.
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT02708329
- Testing
- T-provisional stenting, Mini-crush stenting, CTO coronary angioplasty
- Where
- Russia
- Volunteers
- 146 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Cerebrovascular Disorder
Aneurysms and Carotid Artery Block in Newborns
This study will determine the risk of brain aneurysm (abnormal outpouching of a brain artery) in young adults who had their carotid artery tied off as an infant as part of the extracorporeal membrane oxygenation (ECMO) procedure.
- Trial name
- NCT00646672
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Type 1 Diabetes
Sigi Insulin Management System - A First-in-Human Study in Adults With Type 1 Diabetes
This early feasibility first-in-human study is a prospective single-arm single-center study of Sigi insulin patch pump. After a 1st day and night under medical surveillance during a hotel stay, Sigi system will be evaluated…
- Trial name
- SigiFIH (NCT05973422)
- Testing
- SIGI Insulin Management System
- Volunteers
- 10 people
- Sponsor
- Tandem Diabetes Care, Inc.
Retinal Vein Occlusion
Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edema
The purpose of this study is to examine the effects of Lucentis for active Central Retinal Vein Occlusion with Macular Edema
- Trial name
- NCT00403039
- Testing
- Ranibizumab (Lucentis )
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Vitreous -Retina- Macula Consultants of New York
Acute Coronary Syndrome, Procedural Complication
Decrease Artery Occlusion by Distal Radial Arterial Cannulation in ACS Patients
The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications.
- Trial name
- DONATION (NCT05255939)
- Testing
- distal TRA group, conventional TRA group
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shenzhen People's Hospital
Tooth Extraction
Infiltration Anesthesia vs. Block Anesthesia
Checking the effectiveness of the infiltration technique of local anesthetic agent as an alternative to inferior dental nerve block during tooth extraction
- Trial name
- LAI (NCT06766981)
- Testing
- Infiltration with Articain 4%, Inferior Alveolar Nerve Block
- Where
- 2 sites in Iraq
- Volunteers
- 100 people
- Sponsor
- Sinan A. Shwailiya
Peripheral Arterial Occlusive Disease
CO2-Angiography-Study to Evaluate Diagnostic and Safety to Patients With Peripher Arterial Stenotic or Occlusive Disease.
This randomized study focuses on the diagnostic quality and safety of CO2 application as contrast medium through an innovative injector of AngioDroid in angiography interventions in patients with peripheral arterial occlusive…
- Trial name
- ACDA-RCT (NCT05590182)
- Testing
- Angiography
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Jena University Hospital
Gallbladder Diseases, Cholelithiasis
Impact of Pringle Maneuver on Postoperative Gallbladder Diseases After Hepatectomy
The liver is an organ with a rich blood supply. During liver surgery (hepatectomy), surgeons often temporarily clamp the blood vessels supplying the liver to maintain a clear surgical field and reduce bleeding.
- Trial name
- NCT07452848
- Testing
- Pringle maneuver
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- West China Hospital
Coronary Disease, Coronary Artery Disease
SPIRIT V: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in the Treatment of Patients With de Novo Coronary Artery Lesions (Diabetic Sub-Study)
The purpose of this Clinical Evaluation is a continuation in the assessment of the performance of the XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® EECSS) in the treatment of patients with de novo coronary artery…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- NCT01171820
- Testing
- TAXUS® Liberté™, XIENCE V® EECSS
- Where
- 28 sites in Austria, France and 9 more
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Devices
Retinal Vein Occlusions
Anatomic Outcomes Following Ozurdex Injections
Ozurdex(TM) has recently been FDA approved for use in macular edema secondary to retinal vein occlusion. It remains unclear how quickly the drug works and for how long as the initial studies did not have frequent anatomic…
- Trial name
- NCT01282411
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Barnes Retina Institute
Anemia, Coronary Disease
PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG)
Anemia poses risks during coronary artery bypass grafting (CABG), increasing complications and mortality rates. Blood transfusions in cardiac surgery have negative outcomes, prompting the use of erythropoietin in Patient Blood…
- Conditions
- Anemia, Coronary Disease, Coronary Artery Disease, Coronary Stenosis
- Trial name
- NCT06542393
- Testing
- Erythropoietin, blood transfusion
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Respiratory Failure, Weaning Failure
Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure
Mechanical ventilation is essential in the management of patients in Intensive Care. The approach to patients with prolonged weaning is challenging.In this context, it is vital to implement "diaphragmatic protection" strategies…
- Trial name
- PTPPocc (NCT06040138)
- Testing
- End expiratory occlusion maneuver
- Where
- 4 sites in Argentina
- Volunteers
- 50 people
- Sponsor
- Hospital Italiano de Buenos Aires
Chronic Total Occlusion (CTO), Chronic Coronary Syndrome
FAPI Imaging Predicts Adverse Cardiac Events in Chronic Total Occlusion
Prospective, observational, single-center cohort study Hypothesis Higher myocardial FAPI uptake in CTO patients predicts a greater incidence of major adverse cardiovascular events (MACE) within 12 months after PCI.
- Trial name
- FACT-2 (NCT07020858)
- Testing
- FAPl lmaging
- Where
- China
- Volunteers
- 470 people
- Sponsor
- Lin Zhao
Acute Myocardial Infarction
Stem Cell Therapy in Patients With Myocardial Infarction and Persistent Total Occlusion of Infarct Related Artery
Background: When an acute myocardial infarction occurs, the artery supplying the infarct zone should be opened within twenty four hours of onset of infarction. This has clearly been shown to be beneficial.
- Trial name
- COAT (NCT01625949)
- Testing
- Intracoronary stem cells injection, coronary dilatation and stenting
- Where
- India
- Volunteers
- 40 people
- Sponsor
- All India Institute of Medical Sciences
Injury of Radial Artery
Nitroglycerin Prevents Radial Artery Occlusion
Trans-radial approach (TRA) has becoming popular and widely adopted over the last decade. However, radial artery occlusion (RAO) continues to be one of the limitation of trans-radial access and potentially limits the radial…
- Trial name
- NORAO (NCT02105493)
- Testing
- 500 microgram of Nitroglycerin, Saline 5 mL
- Where
- Indonesia
- Volunteers
- 1,706 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Chronic Total Occlusion of Coronary Artery
Antegrade and Retrograde Dissection and Re-entry Approach for CTO
BACKGROUND：Chronic total occlusion (CTO) angioplasty is one of the most challenging procedures remaining for the interventional operator.
- Trial name
- LOTUS (NCT03769038)
- Testing
- chronic total occlusion
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Basilar Artery Occlusion, Endovascular Treatment
A Comparison of Contact Aspiration Versus Stent Retriever for Acute Basilar Artery Occlusion
Compare the effectiveness and safety of contact aspiration (CA) and stent retriever (SR) in acute ischemic stroke patients with basilar artery occlusion.
- Trial name
- ANGEL-COAST (NCT05615038)
- Testing
- Contact aspiration Thrombectomy, Stent retriever thrombectomy
- Where
- 6 sites in China
- Volunteers
- 338 people
- Sponsor
- Beijing Tiantan Hospital
Occlusion
Effect of T-scan Occlusal Analysis and Adjustment vs Articulating
The aim of this study is to compare two different methods for occlusal analysis of implant - supported prosthesis (T-scan and conventional method with articulating papers) regarding the stresses transmitted to the implants.
- Trial name
- NCT05051878
- Testing
- T-scan, articulating paper
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Diabetes, Macular Edema
Research Study in Patients With Persistent Macular Edema
The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational medication to treat macular edema that persists despite current treatment methods.
- Conditions
- Diabetes, Macular Edema, Diabetic Retinopathy, Retinal Disease
- Trial name
- NCT00035906
- Testing
- DEX PS DDS®
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Allergan
Dental Caries
DPBRN Prevalence of Questionable Occlusal Caries Lesions
The purpose of this study was to investigate the process involved when making decisions about the diagnosis and treatment of questionable lesions, as well as determine if there is any association between lesions progression (or…
- Trial name
- NCT01201447
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
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