Clinical trials: Dental Wear, active
Edentulism Complete, Edentulism
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD/CAM-milled double cross-linked denture teeth, and prefabricated denture teeth.
- Trial name
- Printow (NCT07585162)
- Testing
- CAD/CAM-Milled Denture Base with Milled Denture Teeth, CAD/CAM-Milled Denture Base with Prefabricated Denture Teeth, 3D-printed denture base and teeth
- Volunteers
- 45 people
- Sponsor
- Najla Chebib
Tooth Wear, Orthodontic Extrusion
Orthodontic and Articular Effects of the One-Step No-Prep Protocol
This study investigates how the One-Step No-Prep protocol with orthodontic assistance affects dental and jaw function in adults treated for localized tooth wear.
- Trial name
- OSNPO (NCT07533240)
- Testing
- Low-dose Cone-Beam Computed Tomography
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Mainjot Amélie
Tooth Wear
Clinical Comparison of Different Adhesives in NCCLs
The aim of this randomized, controlled, prospective clinical trial is to evaluate the performances of a universal adhesive in three different application modes, a self-etch adhesive and an etch\&rinse adhesive in restoration of…
- Trial name
- NCT04481087
- Testing
- Clearfil Universal Bond Quick, Clearfil SE Bond, Tetric N-Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Eating Disorders, Oral Health
Oral Indicators for ED Screening
The main objective of this research project is to explore the capability of a standardized, evidence-based study tool (the OHEDs Checklist) in the early identification of oro-dental manifestations potentially indicative of an…
- Conditions
- Eating Disorders, Oral Health, Eating Disorders Symptoms
- Trial name
- OHEDS (NCT07295197)
- Where
- Italy
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Wear, Occlusal
Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus…
- Trial name
- NCT07689032
- Testing
- SHOFU Hard blocks, BRILLIANT Crios
- Volunteers
- 24 people
- Sponsor
- Cairo University
Transdiagnostic Psychopathology, Attrition
Digital Rewards and Retention in a M-health App
Attrition and user engagement are two challenges that eHealth interventions struggle with. Attempts to address this have been previously made through gamification, instructional design and using different types of incentives.
- Conditions
- Transdiagnostic Psychopathology, Attrition, Engagement, Depression, Anxiety
- Trial name
- DIGITALRCT (NCT06883773)
- Testing
- Multipurpose Online Tool, No intervention
- Where
- Romania
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Bucharest
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Dental Erosion
Salivary Function and Dental Changes During GLP-1 Therapy
People who use glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and tirzepatide, may experience changes in their oral health.
- Conditions
- Obesity, Dental Erosion, Saliva Collection, Saliva Altered
- Trial name
- NCT07720466
- Testing
- Unstimulated Whole Saliva Collection, Salivary Analysis, Oral Examination and BEWE Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Child Obesity
Attrition in Pediatric Obesity Management
Our feasibility study will assess the feasibility and acceptability of Family Navigation (FN) to address attrition (dropout) in pediatric obesity management.
- Trial name
- NCT05403658
- Testing
- Family Navigation, Usual Care
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- University of Alberta
Esophagogastric Cancer
A Study of Tooth Erosion in People With Esophagogastric Cancer
The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer…
- Trial name
- NCT05612048
- Testing
- Survey, Intra-oral camera, Optional Salvia sample
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Pediatric Obesity
Qualitative Evaluation of Pediatric Obesity Therapeutic Education Programs
Obesity concerns almost the entire planet and is considered in France as a major public health issue: 17% of children are overweight and 4% obese.
- Trial name
- QUALIPOP (NCT06488235)
- Volunteers
- 32 people
- Sponsor
- University Hospital, Angers
Child Obesity
Applying Navigation and Care to Help Ongoing Retention
Canada's health care system has established numerous clinics over the past 20 years to treat childhood obesity. However, up to 80% of children at these clinics drop out before they finish treatment.
- Trial name
- ANCHOR (NCT07834632)
- Testing
- Family Navigation, Usual Care
- Where
- Canada
- Volunteers
- 252 people
- Sponsor
- University of Alberta
Tooth Wear
Survival and Success of CAD/CAM Restorations After 5 Years of Intraoral Use
This study evaluates the survival and success rates of dental restorations fabricated exclusively using CAD/CAM technology over a period of 5 years.
- Trial name
- NCT07276269
- Testing
- CAD/CAM Digital Restoration Placement, Study of the Survival and Success of Endodontic Posts Using the CAD/CAM Digital Method After 5 Years of Intraoral Use
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
CAD/CAM Space Maintainer, 3D Printing
Evaluation of Clinical Wear and Surface Roughness of Partial Restorations Produced by Additive and Subtractive Manufacturing Methods: A Split-Mouth Randomized Controlled Clinical Trial
The aim of this study is to compare the surface roughness and wear values of crowns fabricated using currently utilized 3D printing and CAD-CAM technologies.
- Conditions
- CAD/CAM Space Maintainer, 3D Printing, Dental Treatment, Dental Disease
- Trial name
- NCT07057401
- Testing
- CAD-CAM Manufactured Crowns, 3D Printed Crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Husna Selinay
Implant Supported Overdenture, Wear, Occlusal
Clinical Evaluation of Conventional and 3D-printed Implant-supported Overdentures Retained With New Attachment Systems
Randomized Crossover Clinical Trial Comparing Two Denture Designs (A and B) Retained by Two Locator Systems (ST and EMI) in Implant Overdenture Patients
- Trial name
- IODs (NCT07580534)
- Testing
- Crossover Assignment
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Sjögren Syndrome
Dental and Periodontal Status of Patients With Sjögren's Syndrome.
Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear…
- Trial name
- CB-SJO (NCT04848870)
- Testing
- Salivary samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Caries, Class II Dental Caries
Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite
Introduction: Resin-based composites (RBCs) have become the gold standard in restorative dentistry due to their superior aesthetics, adhesion, and minimally invasive application.
- Trial name
- NCT07262086
- Testing
- Resins, Composite nanohybrid, Resins, Composite bioactive
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Tooth Wear, Attrition
Prevalence of Tooth Wear and Its Association with Oral Health-related Quality of Life
The aim of this study is to detect the prevalence of tooth wear (All forms of cumulative surface loss of mineralized tooth substance loss due to physical and chemico-mechanical process according to the definition of the European…
- Conditions
- Tooth Wear, Attrition, Erosion
- Trial name
- NCT06665191
- Testing
- No Intervention: Observational study for prevalence of dental wear and its association with quality of life
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prediction of Tooth Wear
Predict Tooth Wear
Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function.
- Trial name
- PREDITOOTH (NCT06681844)
- Testing
- Tooth Shape assessed using an intraoral scanner one after avulsion
- Where
- 5 sites in United States, Belgium and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Hospices Civils de Lyon