Clinical trials: Dentin Caries
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Dentin Caries, Infection
Microbiological and Microscopic Evaluation of Atraumatic Restorative Treatment in Adult Dentition
Atraumatic Restorative Treatment (ART) was proposed as a new and effective method in the 1990s to provide conservative dental treatment to the people living in economically underdeveloped countries, due to lack of dental…
- Trial name
- NCT04813744
- Testing
- Atraumatic restorative treatment
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Caries; Dentin, Dental Restoration Failure of Marginal Integrity
Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
This randomized, multi-centric, controlled clinical trial will assess the effectiveness of a simplified restorative protocol used after the selective carious tissue removal in posterior teeth presenting deep carious lesions.
- Trial name
- (ALFSCaRe) (NCT03933176)
- Testing
- Restoration of carious lesions
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries
Evaluation of Biodentine Versus Glass Ionomer Cement in Treatment of Very Deep Carious Lesions
The aim of this study is to compare the effect of new bioactive dentine substitute (Biodentine) versus glass ionomer cement in very deep carious lesions clinically and radiographically using digital radiography in the terms of…
- Trial name
- NCT02868918
- Testing
- biodentine, glass ionomer cement, DigoraH optium
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Dental Caries, Caries; Dentin
The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration
The aim of this study is to compare the survival rate of the conventional restorations with the Hall Technique in carious primary molars.
- Trial name
- NCT04818658
- Testing
- Assessment of the stainless steel crown using the Hall Technique and Compomer Restoration on primary molars
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Dental Caries
Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining
The purpose of this study is to observe the effects of glass-ionomer cement (GIC) lining on risk of pulpal complications in deep occlusal cavities with resin-based restorations.
- Trial name
- NCT01567514
- Testing
- Glass ionomer cement lining
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries in Children
Potential for Dentine Discoloration of Silver Diamino Fluoride Associated With Potassium Iodide
The objective of this randomized clinical trial will be the comparison of dentine discoloration after treatment with: Silver Diamino Fluoride and Silver Diamino Fluoride associated with Potassium Iodide for caries lesions in…
- Trial name
- NCT04001959
- Testing
- Silver Diamine Fluoride with Potassium Iodide
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Partial Dentin Caries Removal
Radiographic Assessment of Glass Ionomer Restorations With and Without Prior Application of Nano Silver Fluoride in Occlusal Carious Molars Treated With Partial Caries Removal Technique
eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin…
- Trial name
- NCT03193606
- Testing
- nano silver fluoride solution
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Hydroxyapatite
Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults
Target question is as the following one: Does the daily use of a fluoride-free, microcrystalline hydroxyap-atite (HAP) - containing test toothpaste have a non-inferior caries preventing effect in the permanent dentition compared…
- Conditions
- Dental Caries, Hydroxyapatite, Tooth Decay, Dentin, Carious
- Trial name
- CA1 (NCT04756557)
- Testing
- Experimental., Active comparator
- Where
- Poland
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Caries, Dental
Selective Dentine Removal in Primary Teeth
Background There is little information regarding the longevity of the restored tooth, considering the health of the pulp-dentine complex, in children who do not sufficiently cooperate with dental treatment.
- Trial name
- NCT03872037
- Testing
- Selective removal of carious tissue and restoration with Maxxion, Control
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Pulp Disease, Dental, Dental Caries
Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide
The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing…
- Trial name
- NCT04274920
- Testing
- Bioactive Glass, Light cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries,Dental, Deep Caries
Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness
The research question was that in patients with carious posterior permanent teeth, would the electrical impedance device be as valid as digital radiography in estimation of remaining dentin thickness? The proposed hypothesis was…
- Trial name
- NCT06162182
- Testing
- electrical impedance device,, Reference test: Digital Radiographic examination
- Where
- 2 sites in Egypt
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz