Clinical trials: Depression, Anxiety, PTSD
Depression, Anxiety
Study of Effectiveness of Mental Health Interventions Among Torture Survivors in Southern Iraq
1. That the psychotherapeutic intervention - Components-Base Interventions (CBI) - is effective in reducing the severity of mental health symptoms experienced by torture survivors in Southern Iraq. 2.
- Conditions
- Depression, Anxiety, Post-Traumatic Stress Disorder
- Trial name
- NCT01177072
- Testing
- Cognitive Processing Therapy, Components-Based Intervention
- Where
- Iraq
- Volunteers
- 342 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
PTSD - Post Traumatic Stress Disorder, Depression
Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals
This study will examine the effects of Eye Movement Desensitization and Reprocessing (EMDR) group therapy on adults who experienced the April 2025 Silivri earthquake in Turkey.
- Conditions
- PTSD - Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Sleep Quality
- Trial name
- NCT07206381
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Group Therapy
- Volunteers
- 40 people
- Sponsor
- Istanbul Galata University
Post Traumatic Stress Disorder, Depression
CARE Study for Paramedics in Singapore
The purpose of this study is to compare the effectiveness of two different online education courses (Oxford-Online and Mind-Online) for preventing stress related conditions among paramedics who have been working during a period…
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Burnout
- Trial name
- NCT07457801
- Testing
- Oxford-Online, Mind-Online
- Where
- Singapore
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Posttraumatic Stress Disorders, Multiple Sclerosis
The Efficacy of EMDR in Patients With PTSD in Multiple Sclerosis
Multiple Sclerosis (MS) can be associated to many psychological symptoms. One of the most relevant is the experience of distress related to the disease, that can lead to the development of Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01743664
- Testing
- EMDR, Relaxation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- San Luigi Gonzaga Hospital
Anxiety Disorder
SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims
The purpose of this study is to examine the efficacy of escitalopram compared to placebo in reducing Acute Stress Disorder (ASD) symptoms and in preventing the emergence of Post-Traumatic Stress Disorder (PTSD) in patients with…
- Trial name
- NCT00114374
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
Stress, Anxiety
Stress Resilience Training System
The Stress Resilience Training System (SRTS) program is a stress reduction and resilience building system that blends cognitive training to anticipate the effects of stress with advanced biofeedback to mitigate stress effects and…
- Conditions
- Stress, Anxiety, Depression, PTSD
- Trial name
- SRTS (NCT01599624)
- Testing
- Stress Resilience Training System (SRTS), Progressive Muscle Relaxation (PMR)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
PTSD
Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems
The purpose of this study is to evaluate the efficacy of a form of cognitive behavioral therapy (CBT) in a population of individuals with PTSD and common related problems (depression, anxiety or sleep disorders, pain…
- Trial name
- CBT-PTSD-RP (NCT03019497)
- Testing
- Specific Modules, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Université de Montréal
Anxiety Depression, Post Traumatic Stress Disorder
Neuropsychological Sequelae and Long COVID-19 Fatigue
An association of fatigue with post-viral neuropsychological disturbs has been reported. Among patients hospitalized with COVID-19 there is an increased incidence of anxiety and depression symptoms.
- Conditions
- Anxiety Depression, Post Traumatic Stress Disorder, Mental Fatigue, COVID-19
- Trial name
- PostCoV2Psy (NCT05323318)
- Testing
- Neuropsychological Sequelae
- Where
- 6 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Stress Disorders, Post-Traumatic, Anxiety
Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence
This study will determine whether trauma-focused cognitive behavioral therapy (TF-CBT) is more effective than child-centered therapy (CCT) in reducing post traumatic stress disorder (PTSD) in children exposed to domestic violence…
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- NCT00183326
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Anxiety, Depression
Meditation-Based Breathing Training in Improving Target Motion Management and Reducing Distress in Patients With Abdominal or Lung Cancer Undergoing Radiation Therapy
This randomized pilot clinical trial studies the effects of meditation-based breathing training on patients' control of their breathing patterns and breathing-related movement, as well as on their psychological distress and…
- Conditions
- Anxiety, Depression, Digestive System Neoplasm, Lung Neoplasm
- Trial name
- NCT01939210
- Testing
- Educational Intervention, Meditation Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Albert Einstein College of Medicine
Mental Health Issue, Anxiety Disorders
Delivering ICBT to Address Mental Health Challenges in Correctional Officers and Other Public Safety Personnel
Public safety personnel (PSP) have regular and often intense exposure to potentially traumatic events at work and are at higher risk for developing mental health problems such as posttraumatic stress disorder (PTSD).
- Conditions
- Mental Health Issue, Anxiety Disorders, Depressive Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT04666974
- Testing
- iCBT, In-Person CBT
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dr. Nazanin Alavi
Stress Disorders, Post-Traumatic, Acute Stress Disorder
Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers
As part of their work, emergency first responders, such as paramedics and emergency medical dispatchers are exposed daily to traumatic events.
- Conditions
- Stress Disorders, Post-Traumatic, Acute Stress Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT04202042
- Testing
- Psychological first aid, Usual organisational intervention
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Intimate Partner Violence (IPV), Anxiety
Effectiveness of Community-based Approach in Reducing the Intimate Partner Violence (IPV) Exposure and Outcome
Abstract Background: There is a little known about the effectiveness of Community-Based Approach (CBA) on reduction of intimate partner violence (IPV) exposure, anxiety, depression and PTSD symptoms as outcomes in collectivist…
- Conditions
- Intimate Partner Violence (IPV), Anxiety, Depression, Post-traumatic Stress Disorder (PTSD)
- Trial name
- NCT06768502
- Testing
- Community Based Approach (CBA)
- Where
- Rwanda
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Anxiety, Depression
The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective.
The combination of pharmacotherapy and individual cognitive behavioral therapy in a private practice.
- Conditions
- Anxiety, Depression, Obsessive-compulsive Disorder, Personality Disorder
- Trial name
- RAKGEOCBT (NCT06993662)
- Testing
- Group A. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by anxiety disorders and depression., Group B. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by PTSD, Group C. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by obsessive-compulsive disorder.
- Where
- Greece
- Volunteers
- 107 people
- Sponsor
- Rakitzi, Stavroula