Clinical trials: Depression
Suicide Ideation, Suicidal Intention
Classification and Assessment of Mental Health Performance Using Schematics
This is an open enrollment study to collect data for the optimization of smartphone-based algorithms for the early detection of mental health and suicidal risk in a student population.
- Conditions
- Suicide Ideation, Suicidal Intention, Suicide and Depression
- Trial name
- CAMPUS (NCT04275908)
- Testing
- MHSAFE app
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clarigent Health
Sedentary Lifestyle, Postmenopausal Women
Health Benefits of a 6-month Brisk Walking Program in Sedentary Postmenopausal Women
Community-dwelling women aged 55 or over are recruited at public meetings aimed at promoting physical activity in postmenopausal women.
- Trial name
- ACTIMARCH (NCT02094144)
- Testing
- Brisk walking program, physical activity habit
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Subthreshold Depression
tDCS in People With Subthreshold Depression
This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.
- Trial name
- NCT06517121
- Testing
- Personalized Experimental Transcranial Direct Current Stimulation (tDCS), Conventional Experimental Transcranial Direct Current Stimulation (tDCS)
- Where
- Hong Kong
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Obesity, Mood Disorders
Psychosocial Intervention for Women With Mood Disorders Seeking Treatment for Obesity
Women with mood disorders are vulnerable to the negative consequences associated with obesity, and face considerable challenges with adherence to behavioral weight management interventions.
- Trial name
- NCT03743844
- Testing
- Compassion-focused psychoeducation group
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
HIV, Partner Violence
Improving South African Government Workers' Capacities to Deliver HIV Interventions
The purpose of this study is to address the United States Office of AIDS Research highest priorities: improving the workforce, reducing health disparities, and addressing HIV comorbidities.
- Conditions
- HIV, Partner Violence, Malnutrition, Alcohol Use/Abuse
- Trial name
- NCT02957799
- Testing
- Accountable Condition, Control Condition
- Where
- 2 sites in South Africa
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depressive Disorder
Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression
This Phase 2a pilot, exploratory, randomized, double-blind, placebo-controlled, parallel-group trial will estimate whether concurrent fluoxetine alters the antidepressant effect, acute psychedelic experience, or safety of a…
- Trial name
- COGUNILA (NCT06898606)
- Testing
- Psilocybin and Psilocyn, Psychotherapy-assisted session, Fluoxetine
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Federal University of Latin American Integration
Depression, Postpartum Depression
Is Vitamin D Insufficiency and Deficiency Associated With Antepartum and Postpartum Depression?
Our primary aim is to evaluate whether Vitamin D deficiency causes depressive symptoms in antepartum and postpartum depression and whether early correction of Vitamin D deficiency improves these symptoms.
- Trial name
- NCT02272387
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
PET Imaging of mGLuR5 With Drug Challenge
This study is designed to look at that involvement of a process in the brain called the glutamate system in depression. Participants will undergo a screening session, up to two functional Magnetic Resonance Imaging (fMRI) scans…
- Trial name
- NCT01691092
- Testing
- Ketamine
- Where
- 3 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Constipation - Functional, Depressive Symptoms
FMT Treating Constipation Patients With Depression and/or Anxiety Symptoms - Clinical Efficacy and Potential Mechanisms
Constipated patients often have mental problems such as depression and anxiety due to difficult defecation. Our previous studies have proved the efficacy of FMT treating constipation.
- Conditions
- Constipation - Functional, Depressive Symptoms, Anxiety Symptoms, Gut-Brain Disorders
- Trial name
- NCT03233100
- Testing
- FMT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jianfeng Gong
Anxiety, Depression
Bright Light: A Novel Treatment for Anxiety
The primary aim of this research was to examine the influence of bright light on anxiety in high-anxious young adults. In an acute exposure study, participants were randomly assigned to 45 min of either (1) bright light (3,000…
- Conditions
- Anxiety, Depression, Sleep
- Trial name
- NCT01064700
- Testing
- Litebook Bright Light Box
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Depression, Anxiety
Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students
This study was done to investigate the impact of gender differences and exercise intensities on depression and anxiety symptoms among university students
- Conditions
- Depression, Anxiety, University Students, Gender
- Trial name
- NCT07139249
- Testing
- The high intensity interval training, The study moderate continuous training
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Perinatal Depression, PostPartum Depression
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression
There is considerable evidence that most perinatal women at risk for postpartum depression do not engage in mental health services, even when referred by home visiting (HV) programs, primary care physicians, obstetricians, or…
- Trial name
- NCT02979444
- Testing
- Mothers and Babies Groups
- Where
- United States
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Major Depressive Episode
Depressive Symptoms and Subjective Stress in the Course of the Menstrual Cycle - an Ambulatory Assessment Study.
Background: Major changes in female sex hormone concentrations influence the development of depressive symptoms in women. This hypothesis has been thoroughly investigated with regard to the menopause, the postpartal phase and…
- Trial name
- DepCy (NCT04086316)
- Where
- Germany
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
PostPartum Depression
Distant Reiki Therapy on Postpartum Period Fatigue and Depression
This research was conducted to evaluate the effect of Reiki therapy applied to women in the postpartum period on the risk of fatigue and postpartum depression.
- Trial name
- NCT06364436
- Testing
- Reiki energy therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Mental Health, Neurodevelopment
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
The aim of this study is to learn more about how early life experience influences the brain, behaviour, and the immune system later in life.
- Conditions
- Mental Health, Neurodevelopment, ADHD, Autism
- Trial name
- NCT06823492
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Caregiver Stress Syndrome, Anxiety
Supporting Family Caregivers of Persons With Dementia
Based on preliminary work, whereby investigators examined pain management challenges and needs of caregivers of hospice patients with dementia, this team designed a cognitive behavioral intervention informed by the relational…
- Conditions
- Caregiver Stress Syndrome, Anxiety, Depression
- Trial name
- ENCODE (NCT05336344)
- Testing
- ENCODE
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Exercise, Young Adults
The Effect of Exercises on Young Adults
The aim of this study was to assess the treatment effect of plates and conventional exercises on health related quality of life, pain, functional level, psychological state in young adults. Randomised controlled study.
- Conditions
- Exercise, Young Adults, Quality of Life, Pain
- Trial name
- NCT03825614
- Testing
- training
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Depression, Treatment Resistant Depression
Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and…
- Conditions
- Depression, Treatment Resistant Depression, Mood Disorders, Bipolar Disorder
- Trial name
- SHAKTI (NCT06002204)
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression
Attachment Style and Reflective Functioning in CBASP
Cognitive behavioural analysis system of psychotherapy (CBASP) is one of the only psychological models and treatments that has been designed specifically for patients diagnosed with chronic depression.
- Trial name
- NCT02748187
- Testing
- CBASP
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Depression, Treatment Resistant Depression
Investigational TMS Treatment for Depression
This study is aimed to help us learn about the effects of Transcranial Magnetic Stimulation at the forehead versus the left side of the head for treatment of Treatment Resistant Depression.
- Trial name
- NCT03175887
- Testing
- TMS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
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