Clinical trials: Depression NOS
Depression
Receptive Music Therapy for the Treatment of Depression
Depressive symptoms are highly prevalent in the population. According to data from a Zurich longitudinal study, the lifetime incidence rate for severe depressive symptoms is 95%.
- Trial name
- NCT00644527
- Testing
- Purpose designed music and sound listening program
- Where
- Austria
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Artificial Intelligence (AI), Prolonged Grief Symptoms
AI-GF-GNW on Prolonged Grief Reactions
Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved…
- Conditions
- Artificial Intelligence (AI), Prolonged Grief Symptoms, Depression - Major Depressive Disorder, Anxiety
- Trial name
- NCT07589088
- Testing
- AI-Assisted Grief-Focused Guided Narrative Writing, No-Feedback Guided Narrative Writing, Free Writing
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Peking University
Depressive Symptoms, Well-Being, Psychological
Metacognitive Training-Silver BeWell in Older Adults
The present study seeks to examine the feasibility, acceptance and efficacy of Metacognitive Training-Silver (MCT-Silver) BeWell among older adults (ages 60 years and older) delivered in a community setting (e.g.…
- Trial name
- NCT06312241
- Testing
- Metacognitive Training-Silver BeWell
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, Breastfeeding
Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding
"SunnysidePlus" will functionally integrate a web based intervention targeting skills to promote and support breastfeeding, manage mood,and prevent depression.
- Trial name
- NCT04128202
- Testing
- Sunnyside, Sunnyside Plus
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Adolescent Development, Stunting
The Nash-wo-Numa (Childhood Growth & Development) Study
The proposed study will be a cross-sectional study in the District of Matiari, Pakistan. Children ages 9-15 years will be identified from a Matiari District household census scheduled being conducted from December 2016- to May…
- Conditions
- Adolescent Development, Stunting, Depression, Micronutrient Deficiency
- Trial name
- NCT03647553
- Where
- Pakistan
- Volunteers
- 1,385 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Depression
Assessing Anterior Cingulate Brain Activity in People With Late-Life Depression
This study will examine differences in activity of the anterior cingulate cortex, a brain area involved in emotion and cognitive regulation, between older adults with and without depression.
- Trial name
- NCT00926653
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Quality of Life, Insomnia
The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health
Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based…
- Conditions
- Quality of Life, Insomnia, Depression, Anxiety
- Trial name
- NCT05394753
- Testing
- Unified Protocol for mood disorders
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy Volunteers, Major Depressive Disorder
ELE-101 Safety & Tolerability Study in Healthy Participants and Patients With Depression
A study to assess the safety and tolerability of a drug called ELE-101 and see how the body absorbs and removes the drug and how it affects the body in healthy adult participants (Part 1) and in patients with depression (Part 2).
- Conditions
- Healthy Volunteers, Major Depressive Disorder, Depression
- Trial name
- NCT05434156
- Testing
- ELE-101
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Eleusis Therapeutics
Depression, Postpartum
Perinatal Emotion and Relationships Longitudinal Study
This study, funded by the John Templeton Foundation, will examine birth and the early postpartum period (BEPP) as a transformative life experience that may shift women's experience of emotion in such ways as to a) support…
- Trial name
- PEARLS (NCT03027037)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Psychological Distress, Anxiety
Effects of Acupressure on Nurses' Psychological Distress, Depression, Job Stress, Occupational Burnout, and Resilience
This measurement aims to understand the effect of self-acupressure on the Shenmen Point (神門) and (內關) points on the hand on emotional distress, anxiety, depression, stress, work fatigue and adaptability of clinical nurses.
- Conditions
- Psychological Distress, Anxiety, Depression, Nurses
- Trial name
- NCT06946888
- Testing
- Acupressure
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Clinical Depression
Neuromodulation Device Use in Patients With Major Depressive Disorder
Study the neuromodulation device in the treatment of Major Depressive Disorder and associated symptoms. In this study we use the Hamilton Depression Rating Scale (HAM-D), the Quality of Life Scale (QQLS), the Rumination Response…
- Trial name
- NCT04496505
- Testing
- Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical Center of Aurora
Depression
Cognitive Behavioural Couple Intervention Therapy for Chinese Couples With a Depressed Partner
Understanding depression from a relational perspective maybe more meaningful in Chinese culture due to the different values and beliefs among Chinese comparing to those of the Western cultures.
- Trial name
- NCT04590573
- Testing
- Cognitive behavioural couple therapy (CBCT), Emotion focused couple therapy (EFCT), Wait-list control (Control)
- Where
- Hong Kong
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Placebo Effect on Mood Improvement
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement
Although placebo effects on depressive symptoms are well documented, the underlying mechanisms and moderating factors of expectation effects on mood and depression are poorly understood.
- Trial name
- CRC289A07 (NCT05208294)
- Testing
- Sulpiride 400 MG, High expectation manipulation, Low expectation manipulation
- Where
- Germany
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Major Depressive Disorder
Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females
The investigators propose to determine if 8 weeks of dietary augmentation with oral 5g creatine monohydrate daily and 100 mg of 5-hydroxytryptophan (5-HTP) twice daily reduces hypoxia-related depressive symptoms measured by the…
- Trial name
- NCT02922725
- Testing
- 5-hydroxytryptophan and Creatine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brent Michael Kious, MD, PhD
Anxiety, Depression
Group Music Therapy for Chinese Prisoners
The prevalence of psychological problems is high in prisons. Many prisoners have unmet needs for appropriate treatments. Although pilot studies have suggested music therapy to be a successful treatment modality for prisoners…
- Conditions
- Anxiety, Depression, Self-esteem
- Trial name
- NCT01633125
- Testing
- Group music therapy
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Postnatal Depression, Self Efficacy
Effectiveness of 'Supportive Parenting App' on Parental and Newborn Outcomes
The Supportive Parenting App is a theory-based perinatal educational intervention for couples administered through a mobile application.
- Conditions
- Postnatal Depression, Self Efficacy, Parent-Child Relations, Development, Child
- Trial name
- NCT04706442
- Testing
- Supportive Parenting Application
- Where
- Singapore
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Alcohol Abuse, Drug Abuse
Personality-targeted Interventions for Adolescent Alcohol Misuse
Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press).
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Preventure (NCT00344474)
- Testing
- PRE-Venture: Personality Risk Education
- Where
- United Kingdom
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- King's College London
Depression, Mental Health Issue
Economic Evaluation of the MEWE Intervention
Cash transfers have shown promise in preventing intimate partner violence, and in reducing recipients' stress levels. Cash transfers with behavioral or psychological interventions have shown limited effectiveness at reducing…
- Conditions
- Depression, Mental Health Issue, Intimate Partner Violence, Domestic Violence
- Trial name
- MEWE-EE (NCT05598697)
- Testing
- Life Skills Building (LSB) curriculum for males, Life Skills Building (LSB) curriculum for females, Cash transfer to adult females
- Where
- Pakistan
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Well-being, Depressive Symptoms
Integration of Social Art Activities and Qigong for Older People in Nursing Home in Indonesia
This project will be a randomised controlled trial to investigate the effectiveness of an integrated programme by using social art activity (SA) and exercise, for instance, Qigong (QG, a traditional Chinese exercise) as a…
- Trial name
- NCT02957773
- Testing
- Qigong and art activities, Art activities, Qigong
- Where
- Indonesia
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Care Giving Burden, Dementia
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia.
- Conditions
- Care Giving Burden, Dementia, Chronic Pain, Pain Management
- Trial name
- PACE-app (NCT07032350)
- Testing
- Web-based pain management support tool, Usual Pain Management Care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
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