Clinical trials: Depression NOS
Distress, Anxiety
Mobilized Psychoeducation and Skills Based Intervention (Pep-Pal) for Caregivers of Patients With Advanced Illness
The proposed project is a pilot study of the Pep-Pal (Psychoeducation and Skills Based Intervention) versus a treatment as usual control group.
- Conditions
- Distress, Anxiety, Depression
- Trial name
- NCT03002896
- Testing
- Pep-Pal, Treatment as Usual
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post Partum Depression
Maternal Mental Health in the Hospital Setting
Perinatal (around the time of birth) mental health disorders are common difficulties of pregnancy. Perinatal depression is made up of major and minor depressive events during pregnancy and the first 12 months after delivery.
- Trial name
- MMH (NCT03777046)
- Testing
- Standard of Care (SOC), SOC with Psychology Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- Michelle Lopez
Depression
Organized Self-Management Support Services for Chronic Depression
The purpose is to test the effectiveness of an organized care program for chronic or recurrent depression. Using a two-arm design, the investigators will randomly assign 300 participants with chronic or recurrent depression to…
- Trial name
- Stride (NCT01139060)
- Testing
- organized care program for chronic or recurrent depression
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Motivation, Hope
The Effect of Hope-focused Motivational Interview on Individuals Receiving Hemodialysis Treatment
Chronic kidney failure (CRF) is an important health problem in the world and in our country. The use of hemodialysis as a treatment method has prolonged the life span of individuals with CRF; challenging and long treatment…
- Conditions
- Motivation, Hope, Stress, Anxiety
- Trial name
- NCT04927923
- Testing
- hope-focused motivational interview
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Serife Bilge Duran
Implant Supported Overdenture
Impact of Implant Supported Overdenture on Changes of Electromyographic and Brain Activity
The purpose of this study is to evaluate and compare the effects of a mandibular implant-supported overdenture with a mandibular complete denture on electromyographic activity, brain activity, and cognitive performance in…
- Trial name
- NCT05493579
- Testing
- Implant supported overdenture
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Depressive Symptoms, Metacognitive Variables
Do Network Centrality Predict Overall Depression Symptom Reduction With Lifting of Social Distancing Protocols?
The aim of the study is to identify symptom-level intervention targets for depression related to the COVID-19 outbreak. First, we will assess centrality indices of the network of depression symptoms plus mechanism variables…
- Trial name
- NCT04444713
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- Modum Bad
Depression
Reaching Out to Adolescents With Depression
Major Depression is one of the most common mental health disorders in adolescence and is associated with significant impairments in development and functioning.
- Trial name
- ROAD (NCT01140464)
- Testing
- Collaborative care, Enhanced Usual Care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Caregiver Burden, Dementia
Progressive Muscle Relaxation Exercise on Care Burden, Depression, Anxiety, and Stress Levels in Dementia Caregivers
Dementia, which leads to deterioration in cognitive and behavioral functions, is a chronic progressive disease. Since the diagnosis is made, the care needs of the patients increase.
- Trial name
- NCT06143826
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Autism Spectrum Disorder
Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder
This study will assess clinical and behavioral measures along with electroencephalogram (EEG), event-related potentials (ERPS), and eye-tracking (ET) prior to and following a single intermittent Theta Burst Stimulation (iTBS)…
- Trial name
- NCT06142955
- Testing
- MAGSTIM Rapid2 TMS system
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Respiratory Depression
Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section
Spinal Administration of opioids offers segmental analgesia, but has side effects including pruritus, nausea and vomiting, urinary retention, hypotension, and respiratory depression, both early and delayed.
- Trial name
- NCT00544947
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- NHS Greater Clyde and Glasgow
Conduct Disorder, Depression
Anhedonia Beyond Depressive Symptoms in Children and Adolescents With Conduct Disorder
Conduct Disorder (CD) is a common psychiatric disorder among children and adolescents and is characterized by a persistent pattern of behaviors that violate the rights of others or major age-appropriate social norms and rules.
- Trial name
- NCT07849985
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Depression
Optimizing Clinical Screening and Management of Maternal Mental Health: Predicting Women at Risk for Perinatal Depression
The purpose of this study is to determine if medical, biological, psychological, and social risk factors can be used to develop algorithms that will predict perinatal depression (PND).
- Trial name
- NCT03144752
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Emotion Regulation, Stress
Evaluation of a Transdiagnostic Mobile App Intervention Among University Students
This study is a two-armed randomized controlled trial (RCT) aimed at evaluating the effectiveness and adoption of a transdiagnostic mobile app intervention that focuses is on enhancing adaptive emotional regulation (ER) skills…
- Conditions
- Emotion Regulation, Stress, Resilience, Depressive Symptoms
- Trial name
- NCT06224647
- Testing
- Mobile Transdiagnostic Emotion Regulation Intervention
- Where
- Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Erasmus University Rotterdam
Human Immunodeficiency Virus, Sexually Transmitted Infections
Project PRIDE (Promoting Resilience In Discriminatory Environments)
The specific aims are to: 1. Pilot test a randomized controlled trial of Project PRIDE for feasibility for subsequent research projects.
- Conditions
- Human Immunodeficiency Virus, Sexually Transmitted Infections, Anxiety, Depression
- Trial name
- NCT03528135
- Testing
- Project PRIDE
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Houston
Depressive Symptoms, Self-Appraisal
Evaluating and Predicting Response to a Single Session Intervention for Self-Dislike
The investigators are testing whether a single session online intervention for self-dislike decreases: 1. Fear of self-compassion from immediate pre to immediate post intervention 2.
- Trial name
- GOALS (NCT04082052)
- Testing
- Single Session Interventions
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Depression
Interference With Cognitive Control by Transcranial Direct Current Stimulation
Insufficient cognitive control over emotional distracters is characteristic for major depressive disorder (MDD). Hypoactivation of the dorsolateral prefrontal cortex (dlPFC) is associated with this deficit.
- Trial name
- NCT01903538
- Testing
- Cathodal transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Psychological Distress, Impaired Social Functioning
A Scalable Psychological Intervention for Earthquake Survivors in Türkiye
This will be the first pilot randomized controlled trial (RCT) study that investigate the potential effectiveness of individual PM+ among earthquake survivors residing in container cities in Türkiye.
- Conditions
- Psychological Distress, Impaired Social Functioning, Depressive Symptoms
- Trial name
- NCT06026306
- Testing
- Problem Management Plus (PM+)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Koç University
Depression, Child Development
Improving Preterm Outcomes by Safeguarding Maternal Mental Health
The investigators' goal is to optimize the developmental outcomes of preterm infants by preventing depression and improving functioning among their mothers during the critical first year of life.
- Trial name
- NCT01892982
- Testing
- Problem Solving Education tailored to NICU
- Where
- 4 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Aging, Dementia Alzheimers
Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE)
Scalp to cortex distance (SCD), as a key technological parameter of brain stimulation, has been highlighted in the guidelines of non-invasive brain stimulation.
- Conditions
- Aging, Dementia Alzheimers, Parkinson Disease, Dementia Frontotemporal
- Trial name
- NCT05967390
- Testing
- Transcranial Magnetic Stimulation
- Where
- Hong Kong
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mental Disorder, Depression Disorders
The Effect of Acceptance and Commitment Therapy-Based Intervention
Mental health is essential for students' emotional, cognitive, and social well-being. University life presents significant academic, social, and financial challenges, leading to increased stress, anxiety, and depression.
- Conditions
- Mental Disorder, Depression Disorders, Stress, Anxiety
- Trial name
- NCT06885489
- Testing
- Acceptance and Commitment Therapy (ACT) based psychoeducation program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University