Clinical trials: Depression and Quality of Life
Pediatric Cancer, Sickle Cell Disease
FOCUS for Pediatric Sickle Cell Disease and Cancer
Aim. Pilot FOCUS. A pilot randomized controlled trial will compare FOCUS to standard care. Investigators will randomize a total of 60 12- to 18-year-old patients to either FOCUS intervention (n=15 with SCD; n=15 with cancer) or…
- Conditions
- Pediatric Cancer, Sickle Cell Disease, Quality of Life, Depressive Symptoms
- Trial name
- FOCUS (NCT04075877)
- Testing
- FOCUS
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgia State University
Behcet Syndrome
Sleep Related Breathing Disorders, Anxiety, Depression and Quality of Life Assessment in Behcet's Disease
Assessment of Sleep-related breathing disorders, anxiety, depression and quality of life in Behcet's disease.
- Trial name
- NCT05142995
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Intervertebral Disc Displacement, Lumbar Disc Herniation
The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients
When the literature is examined, there are studies examining the relationship between low back pain and anxiety depression, quality of life and LDH in patients with lumbar disc herniation.
- Conditions
- Intervertebral Disc Displacement, Lumbar Disc Herniation, Psychological, Quality of Life
- Trial name
- NCT05804357
- Testing
- Manual Therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Cognition, Affect (Mental Function)
ETASCAI Pilot Project
This pilot study aims to investigate the chronic effects of ETAS® on cognitive, affective and inflammatory outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Inflammation
- Trial name
- NCT06790849
- Testing
- Active 1 ETAS®, Active 2 ETAS®
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Reading
Non Small Cell Lung Cancer
The Effect of Nurse Navigation Program on Lung Cancer Patients
The study aims to determine the effect of the nurse navigation program (LungCaNN), which is performed in line with the supportive care needs of newly diagnosed non-small cell lung cancer patients, on the level of…
- Trial name
- [LungCaNN] (NCT05937425)
- Testing
- LungCaNN
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Akdeniz University
Major Depressive Disorder, Mood Disorder
Laughter Yoga Intervention for People With Major Depressive Disorder
The present study will adopt a non-blinded parallel-group randomized controlled trial design that involves a Laughter Yoga group (intervention) and a treatment-as-usual group (Control).
- Conditions
- Major Depressive Disorder, Mood Disorder, Depression
- Trial name
- NCT03163940
- Testing
- Laughter Yoga
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Major Depressive Disorder, Remission
Quality of Life in Chinese Working and School Age Population With MDD
Major depressive disorder (MDD) is a common mental illness with high prevalence and global burden. Previous studies revealed that over 70% patients in remission still had decreased quality of life, severe function impairment, low…
- Trial name
- NCT04986124
- Testing
- treatment as usual
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Mental Health Center
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Gastric Cancer
Effectiveness of Exercise Program in Improving Quality of Life in Patients With Gastric Cancer Undergoing Gastrectomy
This study will investigate the effectiveness of a rehabilitation program in improving fatigue, negative emotions , sleep quality, circadian rhythms and quality of life in patients with gastric cancer undergoing gastrectomy in…
- Trial name
- NCT04593134
- Testing
- exercise group
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Diabetes Mellitus, Type 2
Diabetes Mellitus and microRNA as Risk Factors for Mild Cognitive Impairment: Impact of Life Style Modification
This is a 2-step study; 1st step was a cross sectional study carried out on 163 consecutive Type 2 Diabetes Mellitus (T2DM) patients employee attending outpatient clinics of the National Research Center (NRC), Egypt.
- Trial name
- NCT04891887
- Testing
- Health education program
- Where
- Egypt
- Volunteers
- 163 people
- Sponsor
- National Research Centre, Egypt
Depressive Symptoms, Depression
Efficacy of an Online Self-help Program for Negative Affect and Depression
The aim of the study is to test Body, breath \& mind (BBM, internet-based self-help program) for its efficacy in reducing depressive symptoms and improving quality of life.
- Trial name
- NCT05293691
- Testing
- Body, Breath & Mind, Moodgym
- Where
- Germany
- Volunteers
- 303 people
- Sponsor
- University of Witten/Herdecke
Chronic Kidney Disease Stage 4 and 5, Exercise
The Effect of Home-Based Exercise on Chronic Kidney Disease Patients
The aim of this study is to investigate the effects of home-based exercise on the risk of sarcopenia, functional capacity, anxiety, depression, fatigue, sleep, and quality of life in patients aged 45 and over with chronic kidney…
- Conditions
- Chronic Kidney Disease Stage 4 and 5, Exercise, Home Based Care, Sarcopenia
- Trial name
- NCT07371858
- Testing
- Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Akdeniz University
Nursing Caries, Nurse's Role
Effects of Postpartum Nurse Navigation Program
The study was planned as a two-group parallel randomized controlled experimental study in order to determine the effects of the nurse navigation program developed for mothers in the postpartum period on mothers' self-care power…
- Conditions
- Nursing Caries, Nurse's Role, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05225987
- Testing
- Postpartum Nurse Navigation Program based care
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Psychological Distress After Coronary Artery Bypass Grafting (CABG)
Telerehabilitation vs. Center-Based Rehab for Psychological Well-being After CABG
This randomized controlled trial aims to determine if a 12-week home-based telerehabilitation (HBTCR) program is as effective as traditional center-based cardiac rehabilitation (CBCR) in improving psychological well-being…
- Trial name
- NCT07232693
- Testing
- Home-Based Telerehabilitation Cardiac Rehabilitation, Usual Care
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Depression, Quality of Life
Impact of COVID-19 Pandemic on Depression and Quality of Life
It is aimed to investigate the depression and quality of life of Turkish society caused by Covid-19 pandemic and reveal the relationship between them
- Conditions
- Depression, Quality of Life, Covid 19, Social Isolation
- Trial name
- NCT04394078
- Testing
- Online survey
- Where
- Turkey (Türkiye)
- Volunteers
- 543 people, healthy volunteers welcome
- Sponsor
- Okan University
Sarcopenic Obesity in Breast Cancer Survival, Muscle Strength Quantitative Trait Locus 1
Effect of Combined Exercise Post-treatment Intervention in Lean Mass Recovery in Breast Cancer Survival.
Breast cancer survival it is affected by the side effects related to the illness, the treatments or even the behavioral factors (e.g.
- Conditions
- Sarcopenic Obesity in Breast Cancer Survival, Muscle Strength Quantitative Trait Locus 1, Cardiopulmonary Capacity, Quality of Life
- Trial name
- WIM1 (NCT01843608)
- Testing
- Physical Intervention
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Politecnica de Madrid
Depression, Anxiety
CES and EGChatbot in Reducing Anxiety, Depression, Insomnia, and Mental Risk
The objective of this three-year study is to provide comprehensive care to young adults presenting with ARMS. The aim is use an exercise group (EGChat) developed by prior study and CES to decrease cognitive mental risks, improve…
- Trial name
- NCT06493695
- Testing
- Both EGChat and CES intervention, Exercise Chatbot, CES (Cranial Electrotherapy Stimulation)
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- China Medical University Hospital
Major Depressive Disorder
Algorithm Guided Treatment Strategies for Major Depressive Disorder
The purpose of this study is to compare treatment outcomes between measurement based Algorithm Guided Treatment and Treatment As Usual strategies in a Chinese population with major depressive disorder.
- Trial name
- AGTs-MDD (NCT01764867)
- Testing
- Escitalopram, Mirtazapine, modified electroconvulsive therapy
- Where
- China
- Volunteers
- 1,080 people
- Sponsor
- Shanghai Mental Health Center
GVHD, Chronic, GVHD - Graft-Versus-Host Disease
Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).
This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease.
- Conditions
- GVHD, Chronic, GVHD - Graft-Versus-Host Disease, GVHD, Quality of Life
- Trial name
- Psych-GvHD (NCT07314892)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Schizophrenia, Caregiver Burden
Psychological Resilience and Quality of Life Among Caregivers of Patients With Schizophrenia
Schizophrenia is a severe and chronic psychiatric disorder that requires long-term care management, placing family members who serve as informal caregivers under substantial psychological, physical, and financial strain.
- Conditions
- Schizophrenia, Caregiver Burden, Quality of Life
- Trial name
- NCT07837479
- Volunteers
- 130 people
- Sponsor
- Assiut University