Clinical trials: Depression in Adults
Preventive Intervention
Preventive Intervention to Promote Healthy Ageing
The aim of the project is the support of healthy ageing of older adults in acommunity. Efficient educational and psychosocial intervention will besuggested and verified to prevent anxiety, depression, and cognitivedisorders of…
- Trial name
- NCT05637177
- Testing
- Anging Wisely, Music therapy, Reminiscence therapy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Emotional Disorder, Stress Related Disorder
Online Transdiagnostic Intervention for Emotional Disorders and Stress-related Disorders
The general objective of this study is to determine the indicators of suitability, clinical utility and satisfaction of the transdiagnostic online intervention for the treatment of emotional disorders and those derived from…
- Conditions
- Emotional Disorder, Stress Related Disorder, Anxiety Disorders, Depression
- Trial name
- NCT05081830
- Testing
- Transdiagnostic online intervention, TCC online intervention
- Where
- Mexico
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Depression
To Demonstrate the Relative Bioavailability of Geneva and Dista (Prozac) 20 mg Fluoxetine Hydrochloride Capsules (Pulvules) In Healthy Adult Males Under Fed and Fasted Conditions
To demonstrate the relative bioavailability of Geneva and Dista (Prozac) 20 mg Fluoxetine Hydrochloride capsules (Pulvules) in healthy adult males under fed and fasted conditions.
- Trial name
- NCT00913588
- Testing
- Fluoxetine HCl 20 mg Capsules Under Fasting Conditions (Geneva Pharmaceutical, Inc.), Fluoxetine HCl 20 mg Capsules Under Fed Conditions (Geneva Pharmaceutical, Inc.), Prozac Fluoxetine HCl 20 mg Capsules Under Fed Conditions (Dista)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sandoz
Anxiety, Depression
Social Factors in the Mental Health of Young Adults: Bridging Psychological and Network Analysis
The central goal of this project is to produce a novel, precise, and comprehensive account of social factors in young adult mental health - using a novel combination of network nominations, ecological momentary assessment, and…
- Conditions
- Anxiety, Depression, Loneliness, Stress
- Trial name
- NCT04771195
- Testing
- Examination of students' naturally occurring social ties
- Where
- United States
- Volunteers
- 9,941 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression
Village-based Intervention for Late-life Depression
Investigators aimed to examine the feasibility and effectiveness of a village-based multilevel intervention for late-life depression.
- Trial name
- NCT04013165
- Testing
- Active control, Village-based intervention
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Physical Activity, Psychosocial Stressors
Improving Physical and Psychosocial Well-being of African American Older Adults
The proposed research effort will: The purpose of this study is as follows: 1. Test the feasibility and acceptability of an eight-week community-based exercise program among AA older adults living in rural areas. 2.
- Trial name
- NCT03716037
- Testing
- Physical Activity for Life (PAL)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Major Depressive Disorder, Depression
A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression
The main goal of this clinical trial is to learn if the active study drug (code name: SP-624) has any effect on the electrical activity of the brain in adult healthy volunteers and in adults with major depression.
- Conditions
- Major Depressive Disorder, Depression, Healthy
- Trial name
- NCT06570369
- Testing
- SP-624
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sirtsei Pharmaceuticals, Inc.
Depression, Anxiety Disorders
Rumination-focused CBT Training for the Prevention of Depression and Anxiety
Depression and anxiety disorders are highly prevalent and associated with reduced quality of life for patients and enormous economic costs for society.
- Trial name
- NCT01223677
- Testing
- Rumination Focused CBT
- Where
- Netherlands
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Psychological Distress, Depressive Symptoms
Nature Photography for Mental Well-Being and Nature Connectedness in Young Adults
This study tests whether a nature photography intervention can improve mental well-being and nature connectedness in young adults with mild emotional distress, and examines self-compassion as a key mechanism in this process.
- Conditions
- Psychological Distress, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT07803367
- Testing
- Nature-Based Mindful Photography, Human-Made Object Photography, Self-Guided Digital Stress Management Handbook
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Irritable Bowel Syndrome With Subthreshold Depression
Lactobacillus-containing Cultured Milk Drink Alleviates Depression Score Among Adults With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is frequently associated with any form of psychiatric comorbidities including subthreshold or subclinical depression.
- Trial name
- NCT05266443
- Testing
- Lactobacillus containing cultured milk drink
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Depressive Symptoms, Allostatic Load
Rise & Thrive: Community-Engagement Intervention for Stress and Depression in Youth.
American youth and young adults face persistent and chronic stressors, which have contributed to a mental health crisis in the United States.
- Conditions
- Depressive Symptoms, Allostatic Load, Metabolic Syndrome
- Trial name
- R&T (NCT07554326)
- Testing
- Rise Together: Community Engagement Intervention, Adulting 101: Life Skills
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Respiratory Depression, Blood Pressure
Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust
The US EPA Clean Air Multiyear research program is moving toward a multi-pollutant approach to the assessment of air pollution in response to recommendations by the NRC 2004 and the BOSC in 2005.
- Trial name
- DEPOZ (NCT01874834)
- Testing
- ozone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Anxiety Depression (Mild or Not Persistent)
Clinical Trials to Evaluate Neurophysiological and Neuropsychological Effects of a Mindfulness-based Intervention
Depression and anxiety are conditions with a high prevalence in the world population and youth are no exception. In developing countries it is reported that given the conditions of social disadvantage, anxiety and depression are…
- Trial name
- PRESENTE-IA (NCT06618339)
- Testing
- Mindfulness-based intervention
- Where
- Mexico
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Healthy Adult Participants
EVASTRESS Healthy Subjects
The goal of this observational study is to learn the feasibility of using a mobile application "Stressometer" to measure perceived stresss levels several times per day.
- Trial name
- EVASTRESS HS (NCT07592078)
- Testing
- Stressometer Mobile Application
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Late-Life Adults, Late-Life Prodromal Depression
Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas
This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults.
- Conditions
- Late-Life Adults, Late-Life Prodromal Depression, Late-Life Depression, Mindfulness
- Trial name
- PredictNPI (NCT07186023)
- Testing
- MBSR, MBWC, MBCI
- Where
- 2 sites in Taiwan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Depressive Disorder, Anxiety Disorders
StayFine: Personalised Relapse Prevention of Anxiety and Mood Disorders in Youths
The current study examines the effectiveness of the StayFine app for relapse prevention of anxiety or depressive disorders in youth using a randomized controlled trial.
- Trial name
- StayFine (NCT05551468)
- Testing
- StayFine guided app-based personalised intervention modules, StayFine app-based monitoring
- Where
- Netherlands
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Ggz Oost Brabant
Iron-deficiency, Iron Deficiency Anemia
Iron Deficiency in Female State Fair Attendees
This study aims to examine iron deficiency symptoms and biochemical iron status based on hemoglobin, hematocrit, ferritin, and total iron binding capacity in menstruating females.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- NCT03228173
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychological Stress, Anxiety
Effects of L-Theanine and Hericium Erinaceus Gummies on Psychological, Cognitive, and Sleep Quality in University Students
The THEA-HEAL Trial is an 8-week randomized controlled study investigating the effects of a daily gummy supplement containing L-theanine and Hericium erinaceus (Lion's mane mushroom) extract on stress, anxiety, cognitive…
- Conditions
- Psychological Stress, Anxiety, Depression, Sleep Quality
- Trial name
- THEA-HEAL (NCT07665840)
- Testing
- gummy intervention
- Where
- Malaysia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Nottingham Malaysia