Clinical trials: Depressive, Symptoms Depressive Disorder, Depression
Depression
Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam
The study is a Hybrid Implementation-Effectiveness study that will primarily test the implementation strategies on provider adoption and implementation quality in three Vietnam provinces.
- Trial name
- NCT04491045
- Testing
- Workshop Training on Multicomponent Collaborative Care for Depression, Supervision, Community-Engaged Learning Collaborative
- Where
- 2 sites in Vietnam
- Volunteers
- 1,382 people
- Sponsor
- City University of New York, School of Public Health
Stroke, Intracerebral Hemorrhage
ACT-group for Stroke Survivors (Pilot Study)
The goal of this clinical pilot trial is to test the feasibility, acceptance and preliminary efficacy of an adapted group psychotherapy manual in stroke survivors with psychological stress.
- Conditions
- Stroke, Intracerebral Hemorrhage, Depressive Symptoms, Anxiety
- Trial name
- NCT06282029
- Testing
- Group Therapy
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Bielefeld University
Anxiety Symptoms, Depressive Symptoms
Back2School - CBT Intervention for School Absenteeism
The main objective of this study is to examine the efficacy of a new psychological intervention, called Back2School, in helping youths with problematic school absenteeism to return to school.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Behavioral Problem, School Absenteeism
- Trial name
- B2S (NCT03459677)
- Testing
- Back2School, Treatment As Usual
- Where
- Denmark
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression
Culturally Sensitive Collaborative Treatment for Depressed Chinese Americans
This study will evaluate the effectiveness of culturally sensitive treatment versus regular care in treating depressed Chinese Americans.
- Trial name
- NCT00227929
- Testing
- Care Management
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Major Depression
Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication According to the ABCB1 Gene
The study evaluates the ABCB1-genotype dependent efficacy of a quick dose-escalation strategy within 28 days of treatment with approved antidepressants that are known substrates of the P-glycoprotein, an efflux pump of the…
- Trial name
- NCT02237937
- Testing
- Paroxetine, Sertraline, Citalopram
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HolsboerMaschmeyer NeuroChemie GmbH
Spinal Cord Injury, Depression - Major Depressive Disorder
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Depression and chronic inflammation are common problems for people with spinal cord injury (SCI). Inflammation has been shown to influence depression which may make it an important treatment target.
- Trial name
- NCT06807528
- Testing
- Intermittent fasting, Behavioral Support Strategies
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Major Depression, Dysthymia
Are Two Antidepressants a Good Initial Treatment for Depression?
Relatively drug naive patients will receive two antidepressant medications as initial treatment.
- Conditions
- Major Depression, Dysthymia, Depression NOS
- Trial name
- NCT00296712
- Testing
- escitalopram + bupropion
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- New York State Psychiatric Institute
Anxiety, Depression / Major Depressive Disorder
The Effectiveness of a One-stop Electronic Clinic for Psychological Service (eClinic) in Hong Kong
With an increasing need for effective and accessible mental health services, telepsychology can be one promising solution to narrowing the gap between demand and supply.
- Conditions
- Anxiety, Depression / Major Depressive Disorder, Common Mental Disorder
- Trial name
- NCT07597967
- Testing
- Internet-based Unified Protocol (UP) Intervention
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Major Depressive Disorder, Recurrent, Unspecified, Major Depressive Disorder, Single Episode, Unspecified
Prospective Multicenter Trial to Explore the Tolerability and Safety of the H-Coil Deep TMS in Combination With Serotonin Selective Reuptake Inhibitor(SSRI)
The purpose of the study is to explore the Tolerability and Safety of the H-Coil deep Transcranial Magnetic Stimulation (TMS) in combination with Serotonin Selective Reuptake Inhibitor (SSRI) for Subjects with Major Depression…
- Trial name
- NCT01361815
- Testing
- H-Coil Deep TMS in combination with SSRIs
- Where
- 19 sites in United States, Canada and 2 more
- Volunteers
- 75 people
- Sponsor
- Brainsway
Depressive Symptoms, Anxiety Symptoms
Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong
The proposed study is a randomized controlled trial (RCT) that aims to examine the effectiveness of cognitive behavioural therapy in reducing depressive and anxiety symptoms for youths in Hong Kong.
- Trial name
- NCT05078424
- Testing
- Cognitive Behavioural Therapy
- Where
- Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Major Depressive Disorder
Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression
This study focuses on treating adolescents with depression. The study has two main purposes. The first is to compare a new form of therapy for depression called Behavioral Activation (BA) to the antidepressant medication…
- Trial name
- NCT01740726
- Testing
- Behavioral Activation, Fluoxetine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
COVID-19, Anxiety
Remote Psychological Intervention for COVID-19 Survivors With AKI and Caregivers (REPICOV-AKI)
The frequency of psychological conditions in recovered COVID-19 patients with Acute Kidney Injury (AKI) and their informal primary caregivers (IPC) is unknown; as well as the effects of psychological therapy in this population.
- Conditions
- COVID-19, Anxiety, Depressive Symptoms, Acute Kidney Injury
- Trial name
- REPICOV-AKI (NCT06522776)
- Testing
- Cognitive behavioral therapy
- Where
- Mexico
- Volunteers
- 98 people
- Sponsor
- Jesus Rivero, MD
Depressive Symptoms, Aging
Digital Gaming Intervention for Older People in Long-term Care
Older people in long-term care (LTC) are often less physically active than their community-dwelling peers. Low physical activity level is associated with more symptoms of anxiety and depression as well as with lower physical…
- Conditions
- Depressive Symptoms, Aging, Loneliness, Sedentary Behavior
- Trial name
- NCT06018974
- Testing
- Yetitablet gaming
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- University of Oulu
Depressive Symptoms
Group- Versus Individual-Mindfulness-Based Cognitive Therapy: a Randomized Trial
The purpose of this study is to determine whether both group and individual mindfulness-based cognitive therapy (MBCT) are effective in reducing depressive symptoms in patients with a chronic somatic disease.
- Trial name
- G/I-MBCT (NCT02314390)
- Testing
- Group-Mindfulness-Based Cognitive Therapy, Individual-Mindfulness-Based Cognitive Therapy
- Volunteers
- 56 people
- Sponsor
- University Medical Center Groningen
Treatment Resistant Depression, Suicidal Ideation
The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
This study aims to explore the safety and tolerability of a single dose of psilocybin (25mg) administered under supportive conditions to adult participants with TRD and chronic suicidal ideation
- Trial name
- NCT05220410
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sheppard Pratt Health System
Premenstrual Dysphoric Disorder, Premenstrual Syndrome
A Placebo-Controlled Study to Investigate the Onset of Action of Paroxetine in Premenstrual Dysphoria
The objective of this study is to explore the onset of action when serotonin reuptake inhibitors are used to treat premenstrual dysphoric disorder
- Trial name
- NCT00516113
- Testing
- paroxetine
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Fibromyalgia, Depression - Major Depressive Disorder
Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients
Repetitive Transcranial Magnetic Stimulation (rTMS) of the motor cortex is a recognized analgesic technique for the treatment of fibromyalgia pain, which represents a largely unmet medical need.
- Conditions
- Fibromyalgia, Depression - Major Depressive Disorder, Chronic Pain
- Trial name
- MultiStimFM (NCT07642882)
- Testing
- rTMS
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Hospital Ambroise Paré Paris
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Healthy, Involutional Depression
Bone Mineral Density in Women With Major Depression
The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than…
- Conditions
- Healthy, Involutional Depression, Osteoporosis
- Trial name
- NCT00001413
- Where
- United States
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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