Clinical trials: Depressive, Symptoms Depressive Disorder, Depression
Post Partum Depression
Effect of Tele-consultation in Addition With Psychiatric Follow-up During COVID-19 in Women Who Have Medical History of Post-partum Depression
Women who were able to benefit from psychiatric follow-up during the quarantine by tele-consultation have a lower risk of anxious and depressive symptoms than those who did not receive follow-up.
- Trial name
- COVIDDEPERINAT (NCT04516668)
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder
Deficits in Emotion Regulation Skills as a Maintaining Factor in Major Depressive Disorder
The primary aim of the study is to evaluate the efficacy of a systematic training of general affect regulation skills (ART) on the reduction of depressive symptom in individuals meeting criteria for major depressive disorder…
- Trial name
- NCT01330485
- Testing
- Affect Regulation Training, Common Factor Control Condition
- Where
- 3 sites in Germany
- Volunteers
- 218 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Depression
Hormonal Levels in Men With Major Depressive Disorder
Subjects will be 1000 men meeting the following inclusion criteria: 1) male, age 18-65 years; 2) meeting DSM-IV criteria for major depressive disorder within the past one year, with a HAM-D score >12.
- Trial name
- NCT00429689
- Testing
- Saliva sample
- Volunteers
- 2,000 people
- Sponsor
- Sheba Medical Center
Major Depressive Disorder
Major Depressive Disorder With Mixed Features
Lurasidone HCl is a compound that is a candidate for the treatment of major depressive with mixed features.This clinical study is designed to test how well Lurasidone works to treat major depressive disorder with mixed features.
- Trial name
- RESOLVE2 (NCT01423240)
- Testing
- Lurasidone 20 mg, Lurasidone 60 mg
- Where
- 27 sites in United States
- Sponsor
- Sumitomo Pharma America, Inc.
Depressive Disorder, Depression - Major Depressive Disorder
Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media
Depression is a highly common mental disorder that often begins in adolescence. Despite its high burden and negative consequences, few young people seek professional help due to, e.g., low mental health literacy and fear of…
- Conditions
- Depressive Disorder, Depression - Major Depressive Disorder, Depression in Adolescence
- Trial name
- NCT07061600
- Testing
- "ich bin alles", Instagram profile that provides educational content
- Where
- Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Depression
Well-being Training for Adolescent Depressive Symptoms (TeenWell Study)
This study is being done to see if the Healthy Minds Program app helps adolescents with elevated depressive symptoms. Up to 200 participants will be on study for 20 weeks.
- Trial name
- NCT06626425
- Testing
- Healthy Minds Program App, Hydro Coach App
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Wisconsin, Madison
Major Depressive Episode (MDE), Beliefs
Belief Update: The Effects of Depression and Antidepressants in Older People
People in good health do not perceive the future in the same way as those suffering from depression. This difference in perception affects behaviour and emotions and warrants further investigation, both before and after treatment…
- Conditions
- Major Depressive Episode (MDE), Beliefs, Beliefs About Future, Depression
- Trial name
- OLDBELIEFS (NCT07681492)
- Testing
- Response to questionnaire
- Where
- 2 sites in France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospital Center Guillaume Régnier
Depressive Symptoms
Social Worker-led Mindfulness-based Intervention for Older People
Preliminary findings from a previous study conducted by the investigators suggest that a task-shared approach with modified mindfulness-based cognitive therapy (MBCT) supported by social workers is beneficial in managing…
- Trial name
- NCT06528132
- Testing
- Mindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters)
- Where
- 13 sites in Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
Major Depression, Dysthymia
Online System for Identifying and Addressing Teen Depression in Primary Care
A novel web-based module (Teen Depression Module or TDM)has been created for assisting primary care providers (PCPs) in screening for and addressing and referring teens with depression.
- Conditions
- Major Depression, Dysthymia, Depressive Symptoms
- Trial name
- Depression (NCT04489485)
- Testing
- Teen Depression Module used for care
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Total Child Health, Inc.
Depression
Trigeminal Nerve Stimulation for Depression: Dose Finding
This study will aim to examine the use of external trigeminal nerve stimulation (TNS) as an adjunctive treatment for adults with major depressive disorder (MDD) when added onto antidepressant medications.
- Trial name
- NCT01343563
- Testing
- Trigeminal Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Depression
Imaging Biomarkers for TMS Treatment of Depression
The purpose of this research is to learn more about how rTMS works to reduce the symptoms of depression. This information can be used to improve the effectiveness of the treatment.
- Trial name
- NCT01900314
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Depression
Testosterone Antidepressant Augmentation in Women
The investigators' hypotheses are: Low-dose testosterone augmentation improves depressive symptoms in women with Major Depressive Disorder (MDD) and antidepressant partial/nonresponse, adjunctive low-dose testosterone is safe and…
- Trial name
- NCT01783574
- Testing
- Testosterone
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Massachusetts General Hospital
Depressive Disorder, Major
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)
The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.
- Trial name
- NCT04442490
- Testing
- SAGE-217
- Where
- 39 sites in United States
- Volunteers
- 543 people
- Sponsor
- Biogen
Depression
PEER Interactive to Inform the Prescription of Medications
Improving the prescription accuracy of psychotropic medications for military personnel diagnosed with neuropsychiatric disorders is imperative to promote accelerated treatment response and recovery.
- Trial name
- NCT04620499
- Testing
- EEG
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University of Ottawa
Nursing Caries, Nurse's Role
Effects of Postpartum Nurse Navigation Program
The study was planned as a two-group parallel randomized controlled experimental study in order to determine the effects of the nurse navigation program developed for mothers in the postpartum period on mothers' self-care power…
- Conditions
- Nursing Caries, Nurse's Role, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05225987
- Testing
- Postpartum Nurse Navigation Program based care
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Depression, Depressive Disorder
OptimizeD Pilot Study
This pilot study aims to explore and refine the trial procedures that will be implemented in a larger-scale clinical trial scheduled to commence in March 2024 (NCT05944926).
- Trial name
- NCT06153004
- Testing
- Healthy Activity Program (HAP), Antidepressant medication (ADM)
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Pain, Depressive Symptoms
Depression and Pain Perseverance Through Empowered Recovery Intervention
African American women who are 50 years of age and older with depressive symptoms, pain and difficulty with mobility will participate in the DAPPER intervention study that includes 8 nurse visits in participants' homes to help…
- Conditions
- Pain, Depressive Symptoms, Frailty, Aging
- Trial name
- DAPPER (NCT04091347)
- Testing
- DAPPER
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Major Depressive Disorder, Neuroinflammation
The Effect of Celecoxib on Neuroinflammation in MDD
Major depressive disorder (MDD) affects an estimated 350 million people worldwide and is a leading contributor to global disease burden.
- Trial name
- NCT04814355
- Testing
- Celecoxib 400 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Stony Brook University
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
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