Clinical trials: Depressive Disorders
Depression - Major Depressive Disorder, Anhedonia
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
The goal of this clinical trial is to systematically categorize potential prohedonic effects of psilocybin in patients with anhedonia in depression. The main questions it aims to answer are: Primary Objectives 1.
- Trial name
- NCT07490353
- Testing
- Psilocybin (Usona Institute), Risperidone 1 MG, MRI
- Where
- Austria
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Depression, Depression, Postpartum
Clinician Managed Interpersonal Psychotherapy
This 12-week study will evaluate the effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) in treating postpartum depression and will compare CM-IPT to standard IPT.
- Trial name
- NCT00043602
- Testing
- Standard interpersonal psychotherapy (IPT), Clinician managed interpersonal psychotherapy (CM-IPT)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Depression, Anxiety
Kintsugi Voice Device Study
The Kintsugi Voice Device Pilot Study is a two arm pilot diagnostic accuracy study. Eligible enrolled participants will complete the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) instruments…
- Trial name
- NCT05554042
- Testing
- Kintsugi Voice Device
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Kintsugi Mindful Wellness, Inc.
Postpartum Depression, Mood Disorders
Whole-Body Hyperthermia for Mood and Anxiety Disorders
This study aims to examine the scientific mechanisms of whole-body hyperthermia (WBH), a novel, rapidly acting, single session antidepressant and anxiolytic therapy.
- Conditions
- Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
- Trial name
- NCT06144294
- Testing
- Whole-Body Hyperthermia, fMRI
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Stress Disorders, Stress
Measuring the Effectiveness of Forest Therapy to Alleviate Stress Among International Students
International students often face high levels of stress, leading to mental health conditions, from factors including cultural and social change, educational system, financial insecurity and family responsibilities.
- Conditions
- Stress Disorders, Stress, Anxiety, Anxiety Depression (Mild or Not Persistent)
- Trial name
- FTIS-2024 (NCT06792656)
- Testing
- standardized Forest Therapy session (120 min)
- Where
- Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- International Nature and Forest Therapy Alliance
Self Concept, Body Fat Composition
Exploring the Effectiveness of the 'Back of the Net' Intervention on Indices of Physical and Psychological Measures
To date very little research has focused on the mental health of young men. The main aim of the proposed research is to explore the effectiveness of a combined exercise and internet-based cognitive behavioral therapy (CBT)…
- Conditions
- Self Concept, Body Fat Composition, Depression, Perceived Social Support
- Trial name
- BTN (NCT00971217)
- Testing
- Exercise, Online Cognitive Behavioural Therapy
- Where
- Ireland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Dublin City University
Depression, Pregnancy
mHealth for Antenatal Mental Health
The aim of this study is to determine the feasibility of using mobile technology for: 1. Implementing the recommendations of the Antenatal and postnatal mental health: clinical management and service guidance NICE guideline for…
- Trial name
- AMHS (NCT02516982)
- Testing
- Whooley Questions, Edinburgh Postnatal Depression Scale, Momentary questions
- Where
- 14 sites in United Kingdom
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Depression Scale Score, Anxiety Symptoms
Unmute's CARE Framework: A Novel Approach to Strengthen the Therapeutic Alliance and Reduce Treatment Disparities
Aim 1: Expand and adapt the CARE framework to train providers to cultivate a strong early alliance with patients who do not share their background (e.g., mismatched dyads).
- Conditions
- Depression Scale Score, Anxiety Symptoms, Functioning, Psychosocial, Working Alliance
- Trial name
- CARE (NCT06625502)
- Testing
- Culturally-Affirming Racial Equity Framework
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York University
Mental Well-being, Mental Health Issue
Evaluation of Online Mental Well-being Intervention for Working Adults
This study aims to evaluate the effectiveness and cost-effectiveness of the online stepped-care mental well-being system together with offline programs in comparison to care as usual.
- Conditions
- Mental Well-being, Mental Health Issue, Mental Health Wellness 1
- Trial name
- NCT05395312
- Testing
- Online blended stepped-care mental well-being platform
- Where
- Hong Kong
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Non-alcoholic Fatty Liver Disease
Urinary Metabonomics of Two Major Patterns of NAFLD
NAFLD(non-alcoholic fatty liver disease, NAFLD) is a common liver disease with a high morbidity which seriously influence people's health.
- Trial name
- NCT02077283
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- ShuGuang Hospital
Anxiety, Depression - Major Depressive Disorder
Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents
The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia…
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Burnout, Insomnia
- Trial name
- NCT07868783
- Testing
- Transcendental Meditation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depressive Disorder, Depression in Adolescence
Evaluation of a Website to Improve Depression Literacy in Adoldescents
The aim of this study is to evaluate the efficacy and acceptability of the website "ich bin alles" (https://www.ich-bin-alles.de/) to improve depression literacy (knowledge about depression, which aid the recognition, treatment…
- Trial name
- NCT05300217
- Testing
- Strategies for promoting mental health, General information about depression
- Where
- Germany
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Abused Women
Qigong Intervention Program for Abused Chinese Women
The purpose of this study is to evaluate the effect of a qigong intervention program on telomerase activity in Chinese women with a history of intimate partner violence.
- Trial name
- NCT02060123
- Testing
- Qigong training, Wait-list control- Health talks
- Where
- China
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Depression, Major Depressive Disorder
Single Session of tACS in a Depressive Episode
Purpose: Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on healthy participants and participants with mood disorders.
- Conditions
- Depression, Major Depressive Disorder, Premenstrual Dysphoric Disorder, Depressive Episode
- Trial name
- SSDE (NCT03449979)
- Testing
- XCSITE100 Stimulator tACS
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prolonged Pregnancy, Sleep Disturbance
Sleep and Depression in Induction of Labour
Randomised trial comparing double balloon catheter for induction of labor between inpatient and outpatient groups. The investigators assess how sleep disturbances and depression of the mother affect to the pain during balloon…
- Conditions
- Prolonged Pregnancy, Sleep Disturbance, Depression
- Trial name
- NCT03380897
- Testing
- Intervention for outpatient group was to go home, Intervention for inpatient group was to stay at ward
- Where
- Finland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Depression, COPD
Prevalence and Predictors of Depression in COPD
Depression adversely affects quality of life in COPD patients, associated with higher rate of exacerbations, admissions and mortality. However, local prevalence rate of depression in geriatric COPD patients remains unknown.
- Trial name
- NCT02415140
- Testing
- Rate of depression
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Depression
Sound Bite-- a Therapeutic Song-writing Program
The research aims to investigate the effectiveness of the therapeutic song-writing program on young people with depressive symptoms. This study adopts a multicentre randomized control trial two arms research design.
- Trial name
- Sound Bite (NCT07371962)
- Testing
- therapeutic song-writing program, Waitlist control group
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Vaginal Discharge, Sexually Transmitted Diseases
Point-of-care Tests for Vaginal Discharge in Nepal
The goal of this clinical trial is to examine if and how the implementation of point-of care-tests (POCT) for sexually transmitted infections in the management of abnormal vaginal discharge reduces the overtreatment with…
- Trial name
- POCT-BRA (NCT05977491)
- Testing
- Health care practitioner is informed of POCT results for CT and NG, Health care practitioner is informed about POCT result for TV and BV, addressing psycholsocial problems
- Where
- Nepal
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Depressive Disorder, Major, Positron-Emission Tomography
Molecular Imaging of Brain Inflammation in Depressive Disorders
In a number of neuropsychiatric disorders such as depression, both brain inflammation and glutamate mediated excitotoxicity (cell death through over-activated stimulation) are suspected to play a key role.
- Trial name
- DiME (NCT02983318)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's