Clinical trials: Depressive Disorders
Depression, PTSD
The Efficacy of an Exercise Program and a Yoga Program in Mitigating Stress and Improving Mental Health Among Employees
To reduce workplace stress and promote mental health, participants were divided into three groups: exercise program, yoga program, and self-care.
- Conditions
- Depression, PTSD, Work Related Stress
- Trial name
- NCT06620783
- Testing
- exercise, yoga, active self-care
- Where
- 2 sites in South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Depression
Reaching Out to Adolescents With Depression
Major Depression is one of the most common mental health disorders in adolescence and is associated with significant impairments in development and functioning.
- Trial name
- ROAD (NCT01140464)
- Testing
- Collaborative care, Enhanced Usual Care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Depression
Comparison Study of Family Practice Interventions for Depression in Adults
To determine if treatment of significant depressive symptoms identified in individuals attending a family practice improves either psychiatric outcome, overall health care costs, or Quality of Life (QOL).
- Trial name
- NCT01975207
- Testing
- Treatment as usual, Internet Intervention, Depression Treatment Pathway
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Bipolar Disorder
Clinical Trial of Pramipexole in Bipolar Depression
The purpose of this study is to examine the safety and effectiveness of the drug pramipexole given in combination with lithium or divalproex for the short-term treatment of acute depression in patients with bipolar disorder.
- Trial name
- NCT00025792
- Testing
- Pramipexole
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
Genetics of Recurrent Early-Onset Depression
This nationwide study will create a DNA collection to permit qualified scientists to search for depression-related genes. More than 750 families with at least two siblings who have experienced major depression are needed for the…
- Trial name
- GenRED (NCT00005914)
- Where
- 6 sites in United States
- Volunteers
- 2,533 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depressive Symptoms
Computerized Cognitive Training in Young Adults With Depression
The purpose of the study is to examine the benefits and mechanism of action of computerized cognitive training (CCT) on mood, neuropsychological deficits, everyday functioning, and brain activity among young adults with a range…
- Trial name
- NCT03869463
- Testing
- Computerized Cognitive Training, Control
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Queens College, The City University of New York
Depression, Anxiety
Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study
This study aims to investigate the association between the use different information sources to obtain information about the COVID-19 pandemic and symptoms of psychopathology (i.e., depression and anxiety).
- Trial name
- NCT04444336
- Testing
- Cross-sectional study examining the impact of information sources to obtain information about COVID-19 on depression and anxiety symptoms
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Depression, Social Stress
Community Resilience Learning Collaborative and Research Network
C-LEARN is designed to determine how to build service program and individual client capacity to improve mental health-related quality of life among individuals at risk for depression, with exposure to social risk factors or…
- Conditions
- Depression, Social Stress, Anxiety, Quality of Life
- Trial name
- C-LEARN (NCT03977844)
- Testing
- Technical Assistance, Community Engagement and Planning, Community Resources (CR)
- Where
- United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Multiple Sclerosis
Online Physical Activity Tracking in Patients With Multiple Sclerosis
This study aims to investigate the effects of regular remote monitoring of physical activity levels of individuals with multiple sclerosis on physical activity levels, psychological health, fatigue and quality of life.
- Trial name
- NCT06283563
- Testing
- Physical activity tracking, No physical activity tracking
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inonu University
Suicide, Depression
Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression
This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.
- Trial name
- NCT06375083
- Testing
- c-CBT for Suicide Prevention, c-CBT or Depression
- Where
- United States
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Alzheimer Disease, Schizophrenia
Multi-center Imaging Genetics Studies in China
To study the impact of genetic and environmental factors on high-level cognition associated neural circuits among healthy young Chinese Han subjects.
- Conditions
- Alzheimer Disease, Schizophrenia, Major Depressive Disorders
- Trial name
- CHIMGEN (NCT02681822)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Anxiety, Depression
Social Factors in the Mental Health of Young Adults: Bridging Psychological and Network Analysis
The central goal of this project is to produce a novel, precise, and comprehensive account of social factors in young adult mental health - using a novel combination of network nominations, ecological momentary assessment, and…
- Conditions
- Anxiety, Depression, Loneliness, Stress
- Trial name
- NCT04771195
- Testing
- Examination of students' naturally occurring social ties
- Where
- United States
- Volunteers
- 9,941 people, healthy volunteers welcome
- Sponsor
- Stanford University
Partner Assisted Interpersonal Psychotherapy, Treatment as Usual
Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression
Purpose: To compare a novel psychotherapy, Partner-Assisted Interpersonal Psychotherapy (PA-IPT), with treatment as usual (TAU) in a sample of pregnant women seeking treatment for Major Depressive Disorder (MDD) at the University…
- Trial name
- NCT01732055
- Testing
- Partner-Assisted Interpersonal Psychotherapy, Treatment as Usual
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Disorder, Depression
Educational Counseling in Improving Communication and Quality of Life in Spouses and Breast Cancer Patients
This randomized clinical trial studies educational counseling in improving communication and quality of life in spouses and breast cancer patients.
- Conditions
- Anxiety Disorder, Depression, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
- Trial name
- NCT01723943
- Testing
- educational intervention, counseling intervention, psychosocial support for caregiver
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Washington
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Depression, Anxiety
Cross-Cultural Differences in the Network Structure of Social Anxiety and Body Dysmorphic Symptoms
This study will examine cross-cultural differences in the network structure of social anxiety and body dysmorphic symptoms across Germany, the United States, and Japan.
- Conditions
- Depression, Anxiety, Body Dysmorphic Disorders
- Trial name
- NCT06962917
- Testing
- Cross sectional study
- Where
- Germany
- Volunteers
- 1,523 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Emotional Intelligence, Anxiety
Improving Mental Health Through Emotional Intelligence Enhancement
The present study examined the effects of an emotional intelligence (EI)-based training program on emotional intelligence and mental health outcomes among secondary school teachers and students in Dhaka City, Bangladesh.
- Conditions
- Emotional Intelligence, Anxiety, Depression, Mental Health
- Trial name
- EI-MH (NCT07591363)
- Testing
- Enhancing Emotional Intelligence
- Where
- Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Dhaka
Major Depressive Disorder
A Study of LY2216684 and Theophylline in Healthy Subjects
The primary objective of this study is to confirm that LY2216684 is not an inhibitor of cytochrome P450 1A2 (CYP1A2) in healthy participants using theophylline as a probe substrate for the enzyme.
- Trial name
- NCT01263106
- Testing
- LY2216684, Theophylline
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Insomnia
Digital Sleep Program for College Students with Insomnia
This randomized controlled trial (RCT) study aims to evaluate the effectiveness of a digital-based multimodal sleep management program compared to a waitlist control group in improving sleep-related outcomes, including insomnia…
- Trial name
- DSP-CS (NCT06853106)
- Testing
- Waitlist control group, digital-based multimodal sleep management program
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Depression
Neuromodulation of Mind-Wandering in Depression
The specific aim of this proposed study is to investigate the feasibility and therapeutic potential of LIFUP in changing negative cognition in depression.
- Trial name
- NCT04832685
- Testing
- BrainSonix Pulsar 1002
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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