Clinical trials: Deprivation
Healthy Volunteers
Sleep Deprivation : Effects on Driving Performance and Central Fatigue
The effects of sleep deprivation (SD) on performance, while contradictory at first glance, are in reality rather clear when exercise duration is considered, i.e. intense/supramaximal versus prolonged exercises.
- Trial name
- PrivSom (NCT01606020)
- Testing
- sleep deprivation, No intervention
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep Deprivation
Predicting Cognitive Resilience Against Sleep Loss
Resilience is the ability to cope effectively and adapt to a wide range of stressful environmental challenges. Sleep loss has been shown to reduce activity in the brain regions responsible for resilience.
- Trial name
- NCT01651429
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Sleep Deprivation, Healthy Volunteers
Effects of Sleep Deprivation on Diaphragm Command During an Inspiratory Endurance Trial in Healthy Volunteers.
The purpose of this study is to assess the impact of sleep deprivation on subjective inspiratory endurance in healthy subjects.
- Conditions
- Sleep Deprivation, Healthy Volunteers, Diaphragm
- Trial name
- NoSleepDiaph (NCT02725190)
- Testing
- Sleepless night, Normal sleep night
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Sleep Deprivation, Sleep Restriction
Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a…
- Conditions
- Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance
- Trial name
- NCT05309473
- Testing
- Philips SmartSleep Acoustic Stimulation Device
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Sleep Deprivation
Protective Effects of Exercise Training
Rationale. Sleep loss is a risk factor for cardiovascular events mediated through endothelial dysfunction. Objective. To determine if 7 weeks of exercise training can limit cardiovascular dysfunction induced by total sleep…
- Trial name
- SOMEX (NCT02820649)
- Testing
- Sleep deprivation
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Sleep
Stable Sleep Pattern Before Sleep Loss
Sleep is now recognized as important for disease prevention. Too little or too much sleep contributes to cardiovascular disease. Leading health organizations recommend adults sleep 7-9 hours per night for optimal health.
- Trial name
- NCT06201390
- Testing
- Sleep consistency
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Sleep Deprivation, Metabolic Disturbance
Biorhythms in Metabolic Tissues
Metabolism is increasingly recognized as being highly regulated by anticipatory biological rhythms (circadian rhythms or "biorhythms"), which are driven by molecular feedback loops, and which are approximately 24 hours long…
- Conditions
- Sleep Deprivation, Metabolic Disturbance, Biological Clocks, Healthy
- Trial name
- NCT03276442
- Testing
- Low-fat dietary intervention, High-fat dietary intervention
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Alzheimer Disease
Effects of Sleep Deprivation on Cerebrospinal Fluid (CSF) Amyloid-beta (Aβ) Dynamics
Introduction: Alzheimer's disease (AD) is characterized by neurodegeneration of the brain in the form of neurofibrillary tangles and plaques containing the amyloid-beta protein (Abeta).
- Trial name
- AWAKE (NCT01194713)
- Testing
- Sleep deprivation
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Medical Center Nijmegen
Sleep Deprivation
Sleep and Maximal Fat Oxidation
Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood.
- Trial name
- Sleep&Fat (NCT07015008)
- Testing
- Sleep deprivation, Sleep place
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy Subjects, Restless Legs Syndrome
Infra-slow Oscillations During Sleep
In this study the investigators plan to systematically characterise infra-slow EEG oscillations during sleep, explore their relationship to the microstructure of sleep, and investigate its role in the physiology and…
- Conditions
- Healthy Subjects, Restless Legs Syndrome, Periodic Limb Movements During Sleep
- Trial name
- SleepD-ISO (NCT02532608)
- Testing
- Acute sleep deprivation
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stephany Fulda
Sleep Deprivation
The Effect of Partial and Complete Sleep Deprivation on Heat Tolerance
The purpose of the present study is to evaluate the effect of partial and complete sleep deprivation on exercise heat tolerance. Twelve healthy young male volunteers will participate in the study.
- Trial name
- NCT01596543
- Testing
- partial and complete sleep deprivation
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Sleep Deprivation
Voice Biomarkers to Predict Excessive Daytime Sleepiness
This study aims at measuring the impact of a night of sleep deprivation over the vocal characteristics of healthy subjects.To do so, the subjects takes a Multiple Sleep Latency Test (MSLT) the day after a night of total sleep…
- Trial name
- SOMVOICE (NCT04942574)
- Testing
- Total sleep deprivation, Normal sleep
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Histamine, Cowhage
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep…
- Conditions
- Histamine, Cowhage, Sleep Deprivation
- Trial name
- NCT06081998
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Sleep Deprivation
Age-related Changes in Sleep-wake Regulation
A sleep deprivation protocol combined with state-of-the-art, simultaneous positron emission tomography and magnetic resonance spectroscopy imaging will be employed to investigate the effects of sleep deprivation and aging on…
- Trial name
- NCT03813082
- Testing
- Prolonged wakefulness
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sleep Deprivation
Menstrual-phase-dependent Differences in Response to Sleep Loss
This study is designed to assess how healthy premenopausal women respond to different patterns of sleep loss at different times in the menstrual cycle.
- Trial name
- NCT05381532
- Testing
- Controlled sleep
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Amblyopia
Light-deprivation Utilized to Mitigate Amblyopia
Amblyopia is an impairment in spatial vision caused by asymmetry in the quality of visual input across the two eyes during childhood.
- Trial name
- LUMA (NCT02685423)
- Testing
- Binocular deprivation 10 days, Vision training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Sleep Deprivation
Effect of Sleep Restriction on Decision Making and Inflammation
hypothesis: sleep restriction in healthy subject trigger alteration of decision making associated with immuno-inflammatory changes inclusion criterias: healthy subjects, men, under 35 years, BMI<26, no sleep troubles…
- Trial name
- NCT01989741
- Testing
- Sleep restriction
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Healthy
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
The aim of this study is to assess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a combination of cognitive physiological endpoints.
- Trial name
- NCT01461174
- Testing
- Modafinil, Donepezil, Memantine
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualissima
Psychosocial Deprivation, Work-Related Stress
Family Supportive Supervisor Training and Workplace Assessment Tool
This study will evaluate the effectiveness of FSST 2.0 (family supportive supervisor training plus support for use of family and sick leaves) using a randomized control trial design.
- Conditions
- Psychosocial Deprivation, Work-Related Stress, Life-work Imbalance
- Trial name
- FSST (NCT05080426)
- Testing
- Family Supportive Supervisor Training 2.0
- Where
- United States
- Volunteers
- 1,175 people, healthy volunteers welcome
- Sponsor
- Work Life Help
Sleep Deprivation
The Effects of Night Call on Intellectual Performance
The purpose of the current proposal will be to examine the clinical performance of both physicians in training as well as experienced faculty in pre and post call situations.
- Trial name
- NCT02697266
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Haleh Saadat