Clinical trials: Depth of Focus
Depth of Focus
Prospective, Multi-center, Non-interventional, Open Label, Randomized (Depth of Focus Testing Sequences), Clinical Study
The purpose of this clinical study is to evaluate the difference in depth of focus measured with two methods in patients implanted with either TECNIS 1-piece Monofocal IOL or TECNIS Eyhance IOL: 1. Trial lens method 2.
- Trial name
- Sierra (NCT06767319)
- Testing
- No intervention
- Where
- 4 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
HIV Infections
HIV Assessment in Fuyang, Anhui Province, China
The purpose of this study was to examine the needs, concerns, stigmas, and social networks of HIV infected former plasma donors (FPDs) and their relatives in Fuyang, Anhui Province, China.
- Trial name
- NCT00094354
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Cataract, Presbyopia
A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs
Since the introduction of intraocular lenses (IOL) in the treatment of cataract, the postoperative accommodative loss of the human eye has been a trending topic.
- Trial name
- NCT03117426
- Testing
- SYMFONY IOL, AT LISA tri 839MP IOL
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation
Modeling and Closed-loop Control of Depth of Anaesthesia
The study evaluates the effect of anaesthetic agents to depth of anaesthesia. An improved PK-PD model wil be developed that will provide the basis for understanding the mechanisms, simulating various scenarios and developing…
- Trial name
- NCT03569839
- Testing
- Propofol
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Periodontitis, Localized Aggressive, Periodontal Diseases
Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket
The aim of this study is to evaluate the accuracy of pulp test in teeth presenting with deep periodontal pocket. The null hypothesis is no significant effect of periodontitis on the accuracy of pulp test.
- Conditions
- Periodontitis, Localized Aggressive, Periodontal Diseases, Endodontic Disease, Endodontic Inflammation
- Trial name
- NCT04399135
- Testing
- Orthopantomogram X-ray view, Endo-Ice, Electric Pulp Tester (EPT)
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qassim University
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Presbyopia
Clinical Outcome of Extended-depth-of-focus Intraocualr Lens (SAV) Implantation
Clinical outcome of extended-depth-of-focus intraocular lens (SAV) implantation
- Trial name
- NCT04391972
- Testing
- SAV
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gingival Recession, Localized
Clinical Evaluation of Tunneled Coronally Advanced Flap v.s Coronally Advanced Flap With Graft for Gingival Recession
The goal of this clinical trial is to evaluate gingival recession depth reduction using tunneled coronally advanced flap compared to coronally advanced flap, both combined with connective tissue graft in patients with isolated…
- Trial name
- NCT06553677
- Testing
- Tunneled coronal advanced flap with connective tissue graft, Coronally advanced flap with connective tissue graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs
Primary objective of this study is to introduce a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients who underwent pseudophakic presbyopic correction with extended-depth of…
- Trial name
- V(λ)'_EDOF (NCT07077967)
- Testing
- Phacoemulsification with EDOF IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Presbyopia, Pseudophakia
Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistance
The primary objective of this study is to compare the postoperative visual acuity curves of patients that underwent one of the following surgical procedures: Insertion of an extended depth of focus intraocular lens with digital…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06460389
- Testing
- Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Presbyopia
Clinical Outcome of Extended-depth-of-focus Trifocal Intraocualr Lens (Triumf) Implantation
Clinical outcome of extended-depth-of-focus trifocal intraocualr lens (Triumf) implantation
- Trial name
- NCT04392024
- Testing
- Triumf
- Where
- South Korea
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gingival Recession, Localized
Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage
Aim of this study is to assess the influence of vestibular depth on root coverage in Miller class III/ Cairo RT2 gingival recession when treated with minimally invasive technique using connective tissue graft.
- Trial name
- NCT06000228
- Testing
- Recession coverage with CTG using minimally invasive access technique in shallow vestibule, Recession coverage with CTG using minimally invasive access technique in deep vestibule
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Cataract, Vision
Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs
The purpose of this study is to evaluate and compare the depth of focus and visual outcomes after implantation of the Acrysof IQ SN60WF aspheric intraocular lens (IOL) and the Acrysof Natural SN60AT spherical IOL.
- Trial name
- NCT00886249
- Testing
- Acrysof IQ, Acrysof Natural IOL
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cataract, Presbyopia
Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens
The purpose of this study is to determine the safety and effectiveness of the IC-8 IOL implanted in one eye and a monofocal or monofocal toric IOL implanted in the fellow eye in accordance with the indication.
- Trial name
- NCT03633695
- Testing
- IC-8 IOL Group, Control Group
- Where
- 21 sites in United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Healthy Controls
Dose-Dependent Effects of Low-Intensity Focused Ultrasound
Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision.
- Trial name
- NCT07099950
- Testing
- Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Parkinson's Disease (PD), Essential Tremor
LIFUS For Neurological Disorders
Low intensity focused ultrasound (LIFUS) has the potential to be used as a means of non-invasive neuro-modulation. To this day, the use of LIFUS is under investigation.
- Conditions
- Parkinson's Disease (PD), Essential Tremor, Orthostatic Tremor, Dystonia
- Trial name
- NCT07417280
- Testing
- LIFUS
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto