Clinical trials: Dermatitis, Allergic Contact
Allergic Contact Dermatitis
Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool
Linalool is currently one of the most used fragrance substances in cosmetic and household products. Previous studies report a high prevalence (5.9-11.7%) of contact allergy to hydroperoxides of linalool (Lin-OOH)1.0% in pet.
- Trial name
- NCT05858723
- Testing
- ROAT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Allergy Research Center, Denmark
Contact Dermatitis, Contact Allergy
Children With Aluminium Contact Allergy: Oral Exposure Study
Aluminium allergy is predominantly seen in children with small itchy nodules in the skin after vaccinations, so-called granulomas.
- Conditions
- Contact Dermatitis, Contact Allergy, Aluminum Allergy
- Trial name
- NCT04921163
- Testing
- sodium aluminium phospate (SALP), Aluminium-free pancake
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- National Allergy Research Center, Denmark
Dermatitis, Allergic Contact, Infectious Diseases
Incidence of Allergic Manifestations and Infectious Episodes in Healthy Term Infants at Risk for Dysbiosis
This study will evaluate the incidence of allergic manifestations (the first of which is atopic dermatitis) and infectious diseases in children fed with an infant formula under real conditions of use.
- Trial name
- SOPRANO (NCT04182425)
- Testing
- Infant formula
- Where
- France
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Bledina
Allergic Contact Dermatitis
Allergy Skin Patch Artificial Intelligence (AI)
The purpose of this research is to assess human and artificial intelligence performance in grading contact dermatitis reactions in healthy volunteers.
- Trial name
- NCT05339750
- Testing
- AI-based smartphone application, Allergen patch
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Contact Dermatitis, Contact Allergy
Children With Aluminium Contact Allergy: Cutaneous Exposure Study
Aluminium is used in many different cosmetic products, including make-up, deodorants and sunscreen. The purpose of this study is to investigate whether these everyday skin products with small amounts of aluminium can cause skin…
- Conditions
- Contact Dermatitis, Contact Allergy, Aluminum Allergy
- Trial name
- NCT04438135
- Testing
- Repeated open application test
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- National Allergy Research Center, Denmark
Dermatitis, Allergic Contact
Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis
The purpose of this study is to compare the effect and safety of rHuPH20 or placebo for the prevention and treatment of skin allergic reaction to nickel. The study drug and placebo will be administered by intradermal injection.
- Trial name
- NCT00928447
- Testing
- rHuPH20
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Halozyme Therapeutics
Contact Allergy, Neuropathic Pain
Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC)
To find out if the use of an intranasal tear neurostimulator (ITN), may be useful in decreasing the pain symptoms felt by patients who experience contact lens discomfort.
- Trial name
- INTAC (NCT04240587)
- Testing
- TrueTear™ intranasal neurostimulator (ITN)
- Where
- United States
- Sponsor
- Tufts Medical Center
Diabetic Foot, Contact Allergy
The Prevalence of Contact Allergies for Wound Dressings In Patients With Diabetic Foot Ulcers (PAID Study)
Rationale: Foot ulcers among diabetics are common. The presence of a contact allergy limits the healing process. Contact allergies for wound dressings are common among patients with ulcers caused by venous insufficiency but less…
- Trial name
- PAID (NCT04085705)
- Testing
- PATCH test
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- Rijnstate Hospital
Allergic Contact Dermatitis
Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents
The objective of the study was to evaluate the diagnostic performance and safety of T.R.U.E. Test allergens in pediatric subjects aged 6-17 years old.
- Trial name
- NCT01797562
- Testing
- Panels 1.3, 2.2 and 3.2 experimental allergens
- Where
- 4 sites in United States
- Volunteers
- 116 people
- Sponsor
- Allerderm
Dermatitis, Contact
Clinical Evaluation of T.R.U.E. TEST in Children and Adolescents
Open, prospective, single-site, non-randomized study of the efficacy and safety of T.R.U.E. TEST allergens in children and adolescents ages 6-18.
- Trial name
- NCT00795951
- Testing
- T.R.U.E. Test
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Allerderm
Allergic Contact Dermatitis
MicroRNA-126 and Its Target VCAM-1Dermatitis to Nickel
Background. Allergic Contact Dermatitis (ACD) is an inflammatory skin disease mediated by direct contact with allergens as nickel, the most common allergen, that may be related with epigenetic changes. Objective.
- Trial name
- NCT04365140
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Allergic Contact Dermatitis Due to Nickel
Short Repeated Nickel Exposures
The former Nickel Directive was introduced in EU in 1994 limiting the release of nickel from items intended for prolonged contact with skin.
- Trial name
- NCT03309215
- Testing
- Experimental stimulation with nickel discs
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Dermatitis, Allergic Contact
Cutaneous and Systemic Reactions to Metal Implants
The purpose of this study is to evaluate if metal patch testing in metal allergic patients is useful for predicting the development of allergic skin disease or systemic symptoms in patients who recieve a metal orthopedic implant.
- Trial name
- NCT02483728
- Testing
- Patch Test
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Allergic Contact Dermatitis
Red Grape Polyphenol Oral Administration to Women Affected by Nickel-mediated Allergic Contact Dermatitis
Nickel (Ni)-mediated allergic contact dermatitis (ACD) is a very common disease worldwide. Our previous findings demonstrated that in vitro supplementation of polyphenols, extracted from seeds of red grape (Nero di Troia…
- Trial name
- Grapolyphen (NCT03902392)
- Testing
- NaturOx Group (A)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Bari
Dermatitis, Allergy
Human Repeated Insult Patch Test
Repeated insult patch test on healthy males and females to determine potential contact irritation or contact allergy in the skin
- Conditions
- Dermatitis, Allergy, Contact Allergy
- Trial name
- NCT03474874
- Testing
- NeoMatriX Collagen Dressing
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NeXtGen Biologics, Inc.
Allergy Skin, Allergy
NeoMatriX Wound Matrix Collagen Dressing Skin Prick Test
The objective of this study is to investigate the potential of NeoMatriXTM Wound Matrix to cause an allergic response to healthy volunteers using a skin prick test.
- Conditions
- Allergy Skin, Allergy, Dermatitis, Allergic Contact
- Trial name
- NCT03522675
- Testing
- NeoMatriX Wound MatriX Collagen Dressing
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NeXtGen Biologics, Inc.
Metal Allergy, Contact Allergy
Metal Allergy In-Stent Restenosis Study
In-stent restenosis remains one of the most challenging problems in patients after coronary artery angioplasty. Angiographically, it is discovered in 10% of the patients after drug-eluting stent (DES) implantation.
- Conditions
- Metal Allergy, Contact Allergy, Restenoses, Coronary, In-stent Restenosis
- Trial name
- RESTALL (NCT03588962)
- Testing
- In-stent restenosis
- Volunteers
- 1,000 people
- Sponsor
- Silesian Centre for Heart Diseases
Allergic Contact Dermatitis
Immune Reactions in Contact Dermatitis Affected Skin
This study hopes to improve the investigators understanding of how the immune system acts in allergic contact dermatitis. In order to reach this goal, normal volunteers, who are suspected of having allergic contact dermatitis…
- Trial name
- NCT01546298
- Testing
- Patch tests
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Allergic Contact Dermatitis Due to Cosmetics
Low Dose Exposure to Oxidized R-limonene - A Repeated Open Application Test (ROAT) Study
This study evaluates the clinical and molecular effect of daily exposure to low doses of the fragrance contact allergen oxidized R-limonene.
- Trial name
- NCT03313232
- Testing
- ROAT with oxidized R-limonene at 1%, 0.3% and 0.1%, ROAT with oxidized R-limonene at 1%
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Dermatitis, Allergic Contact
Intervention Study to Evaluate the Importance of Information Given to Patients With Contact Allergy
The purpose of this study is to determine whether extended information given to patients with contact allergy improves knowledge, treatment efficacy and daily functioning.
- Trial name
- ISICA-13 (NCT01953380)
- Testing
- extended information
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane