Clinical trials: Dermatitis
Eczema Atopic Dermatitis, Eczema
Short-term Topical Application to Prevent Atopic Dermatitis
This is a randomised, open-label, controlled study designed to investigate the effect of short-term neonatal skin barrier protection using a commercially available moisturiser on the prevention of atopic dermatitis and food…
- Conditions
- Eczema Atopic Dermatitis, Eczema, Eczema, Infantile, Food Allergy
- Trial name
- STOP AD (NCT03871998)
- Testing
- Skin barrier protection in the first 2 months of life
- Where
- Ireland
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- University College Cork
Moderate-to-severe Atopic Dermatitis
Phase 1a/1b Study of TRB-061 in Healthy Participants & Patients With Atopic Dermatitis
This Phase 1a/1b randomized, double-blind, placebo-controlled study evaluates the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneously (SC) administered TRB-061 in healthy adults and patients with…
- Trial name
- NCT06934252
- Testing
- TRB-061
- Where
- 19 sites in Australia, New Zealand
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- TRex Bio, Inc.
Atopic Dermatitis, Probiotics
Effect of Probiotics in the Atopic Dermatitis
This study was designed to evaluate the efficacy of probiotics in the treatment of atopic dermatitis. Probiotics in AD patients were effective in reducing SCORAD index levels, but not effective in skin prick test positivity…
- Trial name
- NCT01224132
- Testing
- probiotic ® pur
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Allergic Rhinitis, Allergic Conjunctivitis
Safety and Tolerability of XmAb®7195 in Adult Healthy Volunteers and Adult Subjects With a History of Allergic Rhinitis and/or Allergic Conjunctivitis and/or Atopic Dermatitis
This first-in-human (FIH) study is a randomized, double-blinded, placebo-controlled, ascending dose study to investigate the safety, tolerability, and pharmacokinetics of XmAb7195 in adult healthy volunteers and in adult subjects…
- Conditions
- Allergic Rhinitis, Allergic Conjunctivitis, Atopic Dermatitis
- Trial name
- NCT02148744
- Testing
- XmAb7195
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Radiodermatitis
Management Radiodermatitis in Patients With Breast or Head and Neck Cancer
It aims to evaluate the efficacy of the chamomile recutita gel and urea cream in the prevention of radiodermatitis in patients with breast cancer or head and neck cancer undergoing radiotherapy.
- Trial name
- PRBHNC (NCT02247830)
- Testing
- Chamomilla recutita gel, Urea cream
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Dermatitis, Contact, Dermatitis, Occupational
Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
The purpose of this study is to compare the efficacy of glycerol ointment, triamcinolone acetonide ointment, clobetasol ointment and tacrolimus ointment on irritated skin in a cumulative skin irritation test model using healthy…
- Trial name
- WA+TR_1 (NCT00779792)
- Testing
- clobetasol, triamcinolone acetonide, tacrolimus
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Atopic Dermatitis/Eczema, Type 2 Diabetes
Insulin Sensitivity in Patients With Atopic Dermatitis
The incidence of atopic dermatitis and type 2 diabetes, respectively, has increased over many years. Novel research shows an association between the two conditions.
- Trial name
- AD-IF (NCT03003793)
- Testing
- Hyperinsulinemic euglycemic clamp
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Atopic Dermatitis
A Phase 1 Trial of OPA-15406 Ointment in Healthy Adult Male Subjects
To assess the safety (especially skin findings) and pharmacokinetics by applying 0.3%, 1%, or 3% formulation of 5g OPA-15406 ointment to a 1000 cm2 area as a single-dose and as a multiple-dose twice daily for 2 weeks in Japanese…
- Trial name
- NCT02334787
- Testing
- 0.3% OPA-15406 Ointment, 1% OPA-15406 Ointment, 3% OPA-15406 Ointment
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Celiac Disease, Dermatitis Herpetiformis
Background of Different Phenotypes of Coeliac Disease
The main purpose of this study is to investigate genetic, serological, immunological and microbiata diversities between different coeliac disease phenotypes and to discover applicable prognostic markers for specific phenotypes.
- Trial name
- NCT05597904
- Testing
- Genetic predisposition
- Where
- Finland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Healthy Participants, Healthy Subjects
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases
This study is the first-in-human (FIH) study of BGB-45035. The study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BGB-45035 with both a single dose and multiple doses administered at different…
- Conditions
- Healthy Participants, Healthy Subjects, Healthy Volunteers, Autoimmune Diseases
- Trial name
- NCT06342713
- Testing
- BGB-45035
- Where
- 13 sites in Australia, China and 1 more
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- BeiGene
Atopic Dermatitis
Texting Atopic Dermatitis Patients to Optimize Learning and EASI Scores
The purpose of this study is to determine if sending text messages with treatment reminders and facts regarding atopic dermatitis (AD) to caretakers of children with AD will have a positive effect on the disease severity.
- Trial name
- TADPOLES (NCT02779426)
- Testing
- Text messages
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hand Dermatoses
Hand Dermatitis in the Care and Hospital Staff
Study of the prevalence and risk factors of occupational dermatitis in the hands of caregivers and hospital staff of the Brest CHRU.
- Trial name
- MANUS-PRO (NCT04136574)
- Where
- France
- Volunteers
- 1,138 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Type 1 Diabetes, Allergic Rhinitis
Intervention in Chronic Pediatric Patients and Their Families.
This project consists of a psychological intervention in patients and their families with different chronic diseases in order to carry out a comparative study between medical pathologies to know which are the protective or risk…
- Conditions
- Type 1 Diabetes, Allergic Rhinitis, Allergic Asthma, Asthma
- Trial name
- FACTORADAPT (NCT04476433)
- Testing
- Ten Vida (10Vida)
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Dermatitis
Prevalence of Skin Sensitization and Dermatitis Among Epoxy-exposed Workers in the Wind Turbine Industry.
The goal of this observational study it to learn about the prevalence of skin sensitization and dermatitis among epoxy-exposed workers in the wind turbine industry.
- Trial name
- EPOXY (NCT05891743)
- Testing
- Patch Test
- Where
- Portugal
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Siemens Gamesa Renewable Energy Blades, S.A.
Pterygium, Ocular Surface Disease
Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation
To evaluate the use of cultivated conjunctival epithelial equivalents for the treatment of ocular diseases
- Conditions
- Pterygium, Ocular Surface Disease, Stevens Johnson Syndrome, Chemical Injury
- Trial name
- NCT00346450
- Testing
- Cultivated conjunctival transplantation
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Mild to Moderate Atopic Dermatitis
A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of IN-A002 Ointment in Healthy Adult Male Volunteers and Mild to Moderate Atopic Dermatitis Patients
This study aims to evaluate the safety, tolerability and pharmacokinetic properties of IN-A002 Ointment in healthy adult male volunteers and mild to moderate atopic dermatitis patients
- Trial name
- NCT05729074
- Where
- South Korea
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Itch
Role of Interleukin-13 Pathways on Pain and Itch Sensitivity
Atopic dermatitis (AD) is as chronic, inflammatory skin disorder affecting 20% of the world's population. Intense itch and skin pain are the main symptoms.
- Trial name
- IL-13 (NCT06503510)
- Testing
- Histamine, Cowhage, bovine adrenal medulla (BAM8-22)
- Where
- 3 sites in Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Contact Dermatitis
A Safety, Tolerability, and Dermal Reactogenicity Study of PDC-APB
This is a randomized, double-blind, placebo-controlled, single ascending dose study to assess the safety and tolerability of PDC-APB by intramuscular (IM) injection compared to placebo.
- Trial name
- NCT04853823
- Testing
- PDC-APB
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hapten Sciences, Inc.
Atopic Dermatitis, Rheumatoid Arthritis
MH004 Topical Cream in Healthy Adult Volunteers and Participants With Atopic Dermatitis or Rheumatoid Arthritis
This is a Phase Ia/Ib Study of MH004 in Healthy Adult Volunteers, participants with Mild to Moderate Atopic Dermatitis and participants with Mild to Moderate Rheumatoid Arthritis.
- Trial name
- NCT04815148
- Testing
- MH004 Ia(0.1%), MH004 Ia(0.3%), MH004 Ia(1%)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Minghui Pharmaceutical Pty Ltd