Clinical trials: Dermatologic
Wound Healing, Acute Skin Wounds
Study of LUT017 Gel to Improve Healing of Skin Wounds After Removal of Benign Lesions in Healthy Adults
This is a Phase 1 research study evaluating the safety and potential benefits of a topical gel called LUT017 in helping skin wounds heal after minor skin procedures.
- Trial name
- NCT07463378
- Testing
- LUT017,Topical BRAF inhibitor
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Antoni Ribas
Drug-Related Side Effects and Adverse Reactions, Epidermal Growth Factor
Preventive Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors
The purpose of this study is to evaluate the preventive efficacy of topical EGF cream for dermatologic adverse events related to EGFR inhibitors.
- Trial name
- NCT03051880
- Testing
- Repair Control EGF®, Cream without rhEGF
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- The Catholic University of Korea
Inflammatory Disease, Immune System Disorder
Cross-condition Validation of the Steroid PRO
Testing a questionnaire about treatment with steroids for skin, lung or gastric conditions
- Conditions
- Inflammatory Disease, Immune System Disorder, Gastrointestinal Diseases, Dermatologic Disease
- Trial name
- NCT06314451
- Testing
- Cognitive Interview
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Actinic Keratosis
Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp
This Phase 3, randomized, multi-center, evaluator-blind, vehicle-controlled study evaluates the efficacy and safety of reformulated Levulan Kerastick (aminolevulinic acid HCl 20%) combined with photodynamic therapy (PDT) for…
- Trial name
- NCT07144345
- Testing
- Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle containing excipients only (VEH) without active ingredient, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E
- Where
- 10 sites in United States
- Volunteers
- 160 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Pain, Phlebotomy
Synera Venipuncture Pain
Synera, which is a heated topical patch containing both lidocaine and tetracaine, is intended to reduce the pain associated with venipuncture and superficial dermatologic procedures by numbing the skin.
- Conditions
- Pain, Phlebotomy, Palliative Care
- Trial name
- NCT01744197
- Testing
- Synera (lidocaine 70mg/tetracaine 70mg)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- US Oncology Research
Advanced Malignant Neoplasm, Dermatologic Complication
Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab
This randomized phase II trial studies how well giving spironolactone works in preventing rash in patients with cancer that has spread to other places in the body and are receiving panitumumab and cetuximab.
- Trial name
- NCT01867294
- Testing
- Doxycycline, Management of Therapy Complications, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Academic and Community Cancer Research United
Surgical Wound Infection
Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries
Patients are often counseled to keep a surgical wound dry for 2 to 3 days. The rationale is likely to decrease the risk of infection and bleeding. However, this has never been formally studied.
- Trial name
- NCT01773694
- Testing
- Early Water Exposure
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- Milton S. Hershey Medical Center
Dermatologic Diseases
Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
The researchers believe that pro-angiogenic factors are upregulated in a wide range of dermatologic diseases, including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea, and psoriasis.
- Trial name
- NCT00842283
- Testing
- skin tissue sample
- Where
- 2 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT05080907
- Testing
- Observational
- Where
- 7 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Basal Cell Carcinoma, Squamous Cell Carcinoma
Eversion in Dermatologic Surgery: Is Cosmetic Appearance Improved?
The investigators hypothesize that everting wound edges while suturing surgical sites will result in more aesthetic scars. Additionally, we also hypothesize that small to moderate wound irregularities present at 3 months will…
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
- Trial name
- NCT01770002
- Testing
- Everted suture technique, Non-everted suture technique
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Dermatology/Skin - Other
Animated Video Consultation for Reducing Pre-Operative Anxiety in Outpatient Dermatologic Surgery
The purpose of this study is to evaluate whether the addition of an animated skin surgery educational video to conventional in-person surgery consultation will help reduce pre-operative anxiety in patients awaiting outpatient…
- Trial name
- NCT03344497
- Testing
- VC Group
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Arizona
Dermatologic Disease, Pediatric ALL
Evaluation of the Interest of a Specialist in Dermatology for Dermatopediatric Consultations
Dermatologic diseases, of very different etiology and variable severity, represent a major motivation for consultation (in private consultations and in emergency departments), thus leading pediatricians to frequently turn to…
- Conditions
- Dermatologic Disease, Pediatric ALL, Collaboration
- Trial name
- HLSkinPed (NCT03578718)
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Epidermolysis Bullosa Acquisita
Phase II Pilot Study of Extracorporeal Phototherapy for Epidermolysis Bullosa Acquisita
OBJECTIVES: I. Evaluate immunomodulation with extracorporeal photochemotherapy (ECP) in patients with epidermolysis bullosa acquisita. II. Investigate the effect of ECP on lymphocyte activity.
- Trial name
- NCT00004359
- Testing
- methoxsalen
- Volunteers
- 10 people
- Sponsor
- National Center for Research Resources (NCRR)
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT03848962
- Where
- 2 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Psychological, Sexual Dysfunction
The Impact of Chronic Adolescent Skin Conditions on Sexual Health
Background: Skin conditions are common in young people and are known to adversely affect emotional well-being and quality of life in a range of ways, including negative impact on intimate relationships.
- Conditions
- Psychological, Sexual Dysfunction, Adolescent Development, Interaction, Social
- Trial name
- NCT06397664
- Where
- United Kingdom
- Volunteers
- 91 people
- Sponsor
- Oxford University Hospitals NHS Trust
Skin Toxicity, Immunotoxicity
Novel Skin Care for Immunotherapy- Related Dermatologic Toxicities
Notwithstanding the continuous progress in cancer treatment, patients with cancer still have to cope with quality of life (QoL) - impairing complications.
- Trial name
- ImmunoSkin (NCT04929834)
- Testing
- Hydrating emollient + body lotion for immunotherapy-related side effects
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Nausea and Vomiting, Nausea
Broadening Antiemetics Research by Comparing the Effectiveness of Fosaprepitant and Metoclopramide
The study team proposes a double-blind, comparative effectiveness, randomized controlled trial (RCT) to address the following goal: to determine the relative efficacy and adverse event profile of fosaprepitant compared to the…
- Conditions
- Nausea and Vomiting, Nausea, Vomiting
- Trial name
- BARF RCT (NCT06740812)
- Testing
- Fosaprepitant for Injection, Metoclopramide Injection
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Montefiore Medical Center
Dermatologic Disease
Acceptance of Telemedicine in Dermatology Patients, Physicians and Medical Staff
This study is to investigate the current use and intention to use of teledermatology in Swiss dermatology patients, dermatologists, other physicians and medical staff.
- Trial name
- NCT04495036
- Testing
- data collection (21-items-patient descriptive survey), data collection (23-items-physician descriptive survey)
- Where
- 3 sites in Switzerland
- Volunteers
- 683 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds
LUT017 Gel for Venous Leg Ulcers and Chronic Non-Healing Skin Wounds in Adults
This research study is investigating a new topical medication called LUT017, which is being developed to help heal chronic skin wounds, particularly those known as venous leg ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds, VLU
- Trial name
- NCT07463365
- Testing
- LUT017 gel
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Antoni Ribas