Clinical trials: Desflurane
Early Recovery in Elderly Patients, Cognitive Function
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
The goal of this clinical study is to compare the effects of desflurane versus sevoflurane on early postoperative recovery and cognitive function in elderly patients (aged 60 years and older, ASA I-III) undergoing elective…
- Trial name
- NCT07289945
- Testing
- Sevoflurane, Desflurane
- Where
- Tunisia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Oxygenation, Spinal Surgery
Effects of Different Anesthetic Gases on Hemodynamics, Arterial Oxygenation and Pulmonary Mechanics
The bronchodilator effects of volatile anesthetics have been the subject of many clinical studies. It is known that all volatile anesthetics, especially halothane, have similar effects.
- Conditions
- Oxygenation, Spinal Surgery, Sevoflurane, Desflurane
- Trial name
- NCT06118489
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Desflurane, Anesthesia, General
The Effect of Anthropometrics on Desflurane Rise Time
Desflurane is increasingly used in general anesthesia. Its pharmacokinetic properties are known and its distribution is easily modeled. Yet these models fail in practice.
- Trial name
- NCT06026033
- Testing
- Desflurane induction
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Inhalation Anesthesia, Lung Injury
The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain…
- Trial name
- NCT04645316
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anesthesia
1-1-12 Wash-in for Desflurane Low Flow Anesthesia
We propose a new wash-in technique for desflurane low flow anesthesia with fresh gas flow of O2:N2O 1:1 L/min with desfluraene 12%.
- Trial name
- NCT02013882
- Testing
- 1-1-12 wash-in
- Where
- Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Hemifacial Spasm
Hemifacial Spasm and Desflurane
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm.
- Trial name
- HFS (NCT01726725)
- Testing
- desflurane
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pituitary Adenoma
Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests
This study will compare the effects of sevoflurane, desflurane and total intravenous anaesthesia on pulmonary function tests in patients undergoing endoscopic endonasal transsphenoidal surgery of pituitary gland.
- Trial name
- NCT02709863
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Endothelial Dysfunction
Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx
The glycocalyx is a dynamic and complex biochemical structure composed of proteoglycans, glycoproteins, and soluble proteins. The glycocalyx interacts with various proteins such as albumin and orosomucoid to form a thick surface…
- Trial name
- NCT05068336
- Testing
- desflurane anesthesia, sevoflurane anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Minimal Flow Anesthesia, Low Flow Anesthesia
Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery
This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery.
- Conditions
- Minimal Flow Anesthesia, Low Flow Anesthesia, Robotic Assisted Laparoscopic Abdominal Surgery
- Trial name
- NCT06520943
- Testing
- blood gas analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Abdominal Hysterectomy (& Wertheim)
The Effects of Morphine on Desflurane Consumption and Recovery Time
Combination of volatile and opioid agents are used to achieve unconsciousness, haemodynamic stability and analgesia for surgical prosedures.
- Trial name
- NCT02362022
- Testing
- Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Baskent University
Anesthesia
Effect-site Concentration of Remifentanil for Smooth Induction With Desflurane
Desflurane is a halogenated ether with low solubility, giving rapid induction and emergence from anesthesia This character is suitable for Volatile Induction and Maintenance Anesthesia (VIMA).
- Trial name
- NCT02379715
- Testing
- Remifentanil, Desflurane
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Airway Response
Optimal Dose of Alfentanil for Removal of Supreme Laryngeal Mask Airway During Emergence From Desflurane Anaesthesia
This study aims to determine the optimal dose of alfentanil in suppressing the airway reflexes during supreme LMA removal in anaesthetized adult.
- Trial name
- NCT01371968
- Testing
- alfentanil
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
DNA Damage, Anesthesia
Comparison of the Genotoxicity of Desflurane and Propofol
The purpose of this study is to evaluate if the anesthetics propofol and desflurane can damage DNA according to comet essay in patients submitted to lumbar disc surgery.
- Trial name
- NCT05185167
- Testing
- Anesthetics, General Desflurane Maintenance, Anesthetics, General Propofol Maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Emergence Agitation
Efficacy of Remifentanil in Preventing Emergence Agitation
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane…
- Trial name
- agitation (NCT06539013)
- Testing
- Remifentanil, N2O, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Cough, Hypertension
Optimal Remifentanil Ce for Preventing Severe Cough and Hyperdynamic Response During Tracheal Extubation
Pain, cough, hypertension and tachycardia are frequent events during extubation due to a secondary stimulation of mechanoreceptors located in the airway.
- Trial name
- REX (NCT03132519)
- Testing
- Remifentanil
- Where
- Colombia
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
Ureteral Stent Occlusion, Exposure Laser
Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females
Numerous studies demonstrate that patients have improved immediate recovery characteristics following desflurane anesthesia compared to other volatile agents, including sevoflurane.
- Conditions
- Ureteral Stent Occlusion, Exposure Laser, Ureterostomy; Functional Disturbance, Vaginal Diseases
- Trial name
- NCT01310582
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hahnemann University Hospital
Delirium, Postoperative Cognitive Dysfunction
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality.
- Trial name
- NCT06176144
- Testing
- Desflurane, Sevoflurane
- Where
- China
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Low Flow Anesthesia, Normal Flow Anesthesia
Comparison of Low and Normal Flow Anesthesia in Robotic Assisted Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy has gained increasing popularity compared to open radical prostatectomy with its advantages such as low blood loss, reduced blood transfusion rate, low complication rate, and…
- Conditions
- Low Flow Anesthesia, Normal Flow Anesthesia, Robotic Surgery
- Trial name
- NCT05517551
- Testing
- robotic assisted radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Valvular Heart Disease
Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity
The purpose of this study is to determine desflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery.
- Trial name
- NCT02003885
- Testing
- increment of desflurane
- Where
- South Korea
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Cystoscopes, Baxter Anaesthesia Brand of Desflurane
Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask…
- Conditions
- Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
- Trial name
- NCT01219881
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University