Clinical trials: Detection
Colorectal Cancer
CB-17-08 Augmented Endoscopy System for Mucosal Lesion Detection During Colonoscopy for Colon Rectal Cancer.
The aim of this study is to assess the performance of the CB-17-08 to help endoscopists find potential mucosal polyps during the colonoscopy procedure, without significant noise disturbing the endoscopist attention, nor negative…
- Trial name
- NCT03954548
- Testing
- CB-17-08 CADe
- Where
- 10 sites in United States, Italy and 1 more
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Cosmo Artificial Intelligence-AI Ltd
Chronic Obstructive Pulmonary Disease (COPD)
Temple Health Chest Initiative (THCI 2.0)
Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to significant costs on healthcare…
- Trial name
- NCT06933758
- Testing
- Determine COPD prevalence utilizing spirometry along with CT scans and symptom assessments in the THCI lung cancer screening populatio
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Cancer, Cancer Diagnosis
The DISCOVER Study
The purpose of this research study is to evaluate the possible benefits of screening with an investigational, but commercially available blood test designed to detect many types of cancer.
- Trial name
- DISCOVERY (NCT07390643)
- Testing
- GRAIL Galleri MCED test
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Sepsis, Severe Infection
Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis
The measurement of monocyte volume width distribution (MDW) is intended for use with adult patients presenting to the emergency department (ED), where a CBC with Differential has been ordered, as an aid in the early detection of…
- Trial name
- MDW (NCT03145428)
- Testing
- CBC-Diff Monocyte volume width distribution (MDW)
- Where
- 3 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beckman Coulter, Inc.
Lung Carcinoma
Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial
This clinical trial studies whether tailored patient navigation (PN) works to improve the uptake of lung cancer screening (LCS) in tribal communities in western Washington state.
- Trial name
- NCT07176000
- Testing
- Patient Navigation, Educational Intervention, Best Practice
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colon Polyps
Detection and Classification of Colon Polyps
Colon cancer is the third most common cancer in western society. To prevent colon cancer it is recommended for people to undergo a screening colonoscopy at the age of fifty.
- Trial name
- NCT00825292
- Testing
- Polp removal and identification, colon polyp removal, ETMI colonoscope (ETMI scope is a FDA approved device)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Inflammatory Bowel Diseases, Dysplasia
Image Enhanced Endoscopy IBD
Dye- spray chromoendoscopy remains the recommended gold standard approach for IBD dysplasia surveillance colonoscopy however recently published European and American guidelines recommend either dye-spray or virtual…
- Trial name
- NCT06266104
- Testing
- Image Enhanced Endoscopy Filters
- Where
- Australia
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Royal Perth Hospital
Prostate Cancer
The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
Prostate cancer is the most common non-skin cancer among Veterans and the second leading cause of male cancer death. Current methods of screening men for prostate cancer are inaccurate and cannot identify which men do not have…
- Trial name
- ProGRESS (NCT05926102)
- Testing
- Precision screening intervention, Usual care
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Color Detection of Upper Central Incisors
Study on the Chromatic Perception of Digital Systems in Aesthetic Field
The study under consideration aims to evaluate differences in chromatic perception among three distinct color acquisition methodologies.
- Trial name
- NCT06346548
- Testing
- oral photography
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Paolone Gaetano
Breast Diseases
Lesion Detection of Automated Breast Ultrasound Compared With Handheld Physician-performed Breast Ultrasound
Compare lesion detection of the automated breast ultrasound (ABVS) exam with the conventional handheld (HH) breast ultrasound (US) exam.
- Trial name
- NCT02310776
- Testing
- Supine automated breast ultrasound scanner, High-resolution handheld breast ultrasound
- Where
- 2 sites in United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Northwestern University
CRC, Precancerous Condition
Noninvasive Early Diagnosis of Colorectal Cancer Using Odor-Targeted Capture, Point-of-Care Testing, and Intelligent Analysis
The goal of this observational study is to see whether a new, noninvasive test that analyzes smells (odor) from breath and intestinal gas can help detect colorectal cancer and precancerous growths at an early stage.
- Conditions
- CRC, Precancerous Condition, Healthy
- Trial name
- NCT07620743
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Beijing University of Chinese Medicine
Castration-resistant Prostate Cancer
Liquid Biopsy-based Detection of Resistance to Targeted Therapy in Prostate Cancer Patients
This study will prospectively compare liquid-biopsy based methods for prediction of resistance under androgen-receptor signaling inhibitors.
- Trial name
- PEARL (NCT03601143)
- Testing
- Blood samples prior to a new line of AR-targeted therapy
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Irritable Bowel Syndrome
Confocal Laser Endomicroscopy, IBS and Stress
After standard endomicroscopy with fluorescein to investigate for dysplasia in Barrett's esophagus the endoscope will be forwarded into the 2nd part of the duodenum.
- Trial name
- NCT02316132
- Testing
- Stress, Control
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Breast Cancer
Fujifilm DBT Plus S-View Versus FFDM Alone in the Detection of Breast Cancer - A Pivotal Study
The purpose of the pivotal reader study is to assess the comparative accuracy of Fujifilm DBT plus S-View versus FFDM in the detection of breast cancer.
- Trial name
- NCT03501693
- Testing
- DBT plus S-View, FFDM Alone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Neoplasms, Breast Cancer Detection
Diagnostic Accuracy of Carebot AI MMG in Mammography Screening: Multicenter MRMC Study
This study evaluates the diagnostic performance of Carebot AI MMG, an artificial intelligence (AI)-enabled medical device for evaluating mammograms.
- Conditions
- Breast Neoplasms, Breast Cancer Detection, Breast Cancer - Female, Breast Cancer Screening
- Trial name
- CARE-MMG-MRMC (NCT07298252)
- Testing
- Carebot AI MMG software analysis
- Where
- 4 sites in Czechia, Slovakia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Carebot s.r.o.
Gastric Cancer
Novel Screening Modality for Early Gastric Cancer
Potential patients will be recruited at participating sites based on routine care with clinical indications for upper endoscopy.
- Trial name
- NCT04114006
- Where
- Honduras
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Coronary Arterial Disease (CAD)
Non-invasive Detection of Coronary Artery Stenosis
The aim of this viability study is to investigate using a novel medical device, the potential for detecting partial blockages in the arteries within the wall of the heart (coronary artery stenosis).
- Trial name
- NIDCAS (NCT06750016)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nilocas
Child, Anesthesia
Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in Children
The purpose of this study is to find an optimal inspiratory pressure to provide adequate tidal volume and prevent gastric insufflation in pediatric patients.
- Trial name
- NCT02471521
- Testing
- Mask ventilation, Rocuronium
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pregnancy
Effectiveness of Online-Based "Pregnant Women Care Cadres" Intervention on Husband Support in Early Detection of High Risk in Medan Maimun Area
The goal of this quasi-experimental study is to evaluate whether an online-based "Caring for Pregnant Women" intervention delivered through community health cadres can improve husband support in the early detection of high-risk…
- Trial name
- NCT07430033
- Testing
- Online-Based "Caring for Pregnant Women" Intervention Through Community Health Cadres to Enhance Husband Support in Early Detection of High-Risk Pregnancy
- Where
- Indonesia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Siti Saidah Nasution
Cancer
Pan-canceR Early DetectIon projeCT (PREDICT)
PREDICT is a prospective, multicenter study for the early detection of pan-cancer through cell-free DNA (cfDNA) methylation-based model, in which approximately 14,000 participants will be enrolled.
- Trial name
- NCT04817306
- Testing
- Multi-cancer early detection test
- Where
- 3 sites in China
- Volunteers
- 14,026 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
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