Clinical trials: Detection
Lung Biopsy
Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy
Objective: The goal of this study is to evaluate the sensitivity and specificity of the presence of pneumothorax on a 4-hour CXR after image-guided transthoracic lung biopsy (TTLB) for diagnosing subsequent clinically significant…
- Trial name
- NCT06563167
- Testing
- CXR
- Where
- Hong Kong
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
Acute Myocardial Infarction (AMI)
POCT Detection for Blood Concentration of Tirofiban in Acute Myocardial Infarction Based on Azo-POP Probe.
The goal of this observational study is to monitor blood drug concentration during the use of tirofiban, predict the occurrence of intraoperative and postoperative complications related to interventional therapy, and evaluate the…
- Trial name
- NCT06836531
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Cancer, Colo-rectal Cancer
Gut Microbiota and Color-rectal Cancer.
This clinical trial is focused in the development of a screening test for the people at risk of colo-rectal cancer (aged more than 50 years old), valid and safe, improving the screening prognosis increasing the sensitivity and…
- Conditions
- Cancer, Colo-rectal Cancer, Diagnoses Disease, Microbiota-related Disease
- Trial name
- CCR-microbiota (NCT04662853)
- Testing
- Gut microbiota determination from feces samples.
- Where
- Spain
- Volunteers
- 153 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Pregnancy
Accuracy of Whole-Blood Testing for Rapid Detection of Pregnancy
It is common practice in the emergency medicine department to rapidly assess pregnancy status through the use of either urine or serum in pregnancy tests.
- Trial name
- NCT00373139
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Autism Spectrum Disorder, Neurodevelopmental Disorders
A Smart Toy for Motor Function and Early Assessment of Children With Possible Autism
Autism diagnostic referrals across the UK have doubled within the last five years. Covid-19 has further delayed diagnostic pathways, while innovation has not kept pace in assisting clinical teams with low cost, fast, and…
- Trial name
- Tangiball (NCT04980677)
- Testing
- Tangiball
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sussex Community NHS Foundation Trust
Genital Mycoplasma Infection, High Risk Pregnancy
Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy
Subclinical urogenital infections have been implicated in up to 70% of adverse pregnancy outcome, especially preterm labor and delivery.
- Conditions
- Genital Mycoplasma Infection, High Risk Pregnancy, Preterm Labor
- Trial name
- NCT01281319
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Promyco Diagnostics
Anastomotic Leak
Early Detection of Postoperative Anastomotic Leak by CT
Postoperative anastomotic leak is rare but life threatening complication after gastric cancer surgery. Early diagnosis is key to minimize other hazards which are caused by anastomotic leak.
- Trial name
- NCT03632395
- Testing
- computed tomography
- Where
- China
- Volunteers
- 110 people
- Sponsor
- BIRENDRA KUMAR SAH
Colon Cancer, Polyp
Chromocolonoscopy for the Detection of Flat Adenomas in Routine Colorectal Cancer Screening.
The proposed research aims to determine the prevalence, size, shape and histology of flat colorectal neoplasms in a cohort of asymptomatic, average-risk individuals presenting for screening colonoscopy.
- Conditions
- Colon Cancer, Polyp, Adenoma
- Trial name
- NCT00245492
- Testing
- Chromocolonoscopy
- Where
- 3 sites in United States
- Volunteers
- 792 people, healthy volunteers welcome
- Sponsor
- Indiana University
Type 1 Diabetes
Fault Detection, Zone MPC and DiAs System in T1D
This is a randomized crossover study testing the efficacy of the Fault Detection algorithms using the Zone MPC algorithm and DiAs artificial pancreas platform in adult patients with type 1 diabetes.
- Trial name
- ZoneMPC (NCT02773875)
- Testing
- Artificial pancreas system (Algorithm + CGM + pump)
- Volunteers
- 20 people
- Sponsor
- Rensselaer Polytechnic Institute
Colorectal Adenoma
Development and Validation of an Artificial Intelligence-assisted System for Bowel Cleanliness Assessment Based on Withdrawal Distance Weighting
To address the limitations of current AI-based systems that rely on the assumption of a "constant withdrawal speed," this study proposes the integration of the UPD-3 endoscopic positioning system.
- Trial name
- NCT07150130
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Fudan University
Endometrial Cancer, Endometrial Cancer Precursors
The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons
BACKGROUND: Endometrial cancer is a common and deadly cancer for women. It is getting more common and deadly because risk factors like age and obesity are increasing.
- Conditions
- Endometrial Cancer, Endometrial Cancer Precursors, Ovarian Cancer, Complex Atypical Endometrial Hyperplasia
- Trial name
- DETECT (NCT03538665)
- Where
- United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Human Papillomavirus Infection
Comparison of Self-collection Using Dry Compared to Wet Swabs for HPV Detection
This study will compare the performance of self-collected vaginal swabs, transported without liquid media (dry swabs) and self-collected vaginal swabs, transported in liquid media (wet swabs) for detection of hrHPV DNA LBC as the…
- Trial name
- HPV (NCT06213051)
- Testing
- • COPAN Self-collection FLOQSwabs® (COPAN, Italy)
- Where
- Kenya
- Volunteers
- 1,306 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Colorectal Cancer, Stage II and III
Simultaneaous Detection of Quantitative Somatic Alterations Using the Qantitative Multiplex Pcr of Short Fluorescent Fragments Method (QMPSF) in Stage II-III Colon Cancer: a Prospective Study
Lymph node involvement remains the main criteria for postoperative chemotherapy in patients with colon cancer (CC) without distant metastasis.
- Trial name
- Code Barre (NCT02110329)
- Testing
- evaluation of the recurrence rate according to molecular analysis
- Where
- 3 sites in France
- Volunteers
- 401 people
- Sponsor
- University Hospital, Rouen
Chronic Kidney Diseases
Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm
One in 10 adults in Region Stockholm have chronic kidney disease (CKD), which dramatically increases healthcare costs and the risk of medication errors or adverse health outcomes, including cardiovascular disease and death.
- Trial name
- ALMA-CKD (NCT06386172)
- Testing
- Clinical decision support trigger
- Where
- Sweden
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
The Study Focuses on the Saliva as Potential Source of Early Detection of Oral Cancer
EVALUATION OF SALIVA AS LIQUID BIOPSY FOR EARLY DETECTION OF ORAL CANCER IN PATIENTS WITH ORAL-SUBMUCOUS FIBROSIS (OSMF)
Oral cancer is the top cancer in Pakistan, accounting for 27%, and it has a high mortality rate due to late-stage diagnosis. It primarily affects the lips, tongue, cheeks, and floor of the mouth.
- Trial name
- Sal (NCT07122128)
- Testing
- saliva a a diagnostic tool for early detection of oral cancer
- Where
- Pakistan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Gastric Cancer
Evaluation of a Computer-aided Diagnosis System (CADx) in the Early Detection of Gastric Cancer in France. Cancer in France.
Upper gastrointestinal (GI) cancers are one of the most common cancers worldwide. Except for cardia cancers, the incidence of gastric cancer has decreased consistently since 1980, but remains at a high level.
- Trial name
- EGC-France (NCT05928819)
- Testing
- Evaluation of the proportion of gastric neoplastic lesions detected by a computer-aided diagnosis system (CADx) compared with experienced endoscopists.
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon
Colonoscopy
Impact of Real-time Automatic Quality Control System on Colorectal Adenoma Detection
The purpose of this study was to assess the performance of automatic quality-control system (AQCS) in real-time quality control of colonoscopy.
- Trial name
- NCT04901130
- Testing
- Computer-aided Real-time Automatic Quality Control System (AQCS)
- Where
- 6 sites in China
- Volunteers
- 1,254 people
- Sponsor
- Shandong University
Difficult Airway
Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients
the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients
- Trial name
- NCT06700265
- Where
- Egypt
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Metastatic Prostate Cancer
Evaluation of 18F-DCFBC PSMA-based PET Imaging for Detection of Metastatic Prostate Cancer
This research is being done to see if an investigational radioactive drug called 18F-DCFBC can help us find cancer that has spread (metastatic disease) from its original site in people who have cancer in their prostate to other…
- Trial name
- NCT01815515
- Testing
- 18F-DCFBC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pulmonary Infection
mNGS for Detection of Pathogens for Pulmonary Infection
Pulmonary infections remain the leading causes of morbidity and mortality among patients worldwide. Pathogen identification is crucial yet difficult for the majority of the cases.
- Trial name
- NCT03798925
- Testing
- None Intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sir Run Run Shaw Hospital
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