Clinical trials: Detection
COVID - 19, Influenza A
Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test
This observational study aims to evaluate the diagnostic performance of an investigational Influenza A/B and COVID-19 test in patients presenting with signs and symptoms of respiratory infection.
- Conditions
- COVID - 19, Influenza A, Influenza B
- Trial name
- NCT07190131
- Testing
- Investigational Flu A/B And Covid-19 Diagnostic Test
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 588 people
- Sponsor
- iHealth Labs inc
Colorectal Cancer, Adenoma
A Multi-center Trial to Establish a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA
In this study, the investigators establish a model for the early diagnosis of colorectal cancer based on the detection of 5-hydroxymethylcytosine (5-hmC) in training group and validate the effectiveness of the model using a…
- Trial name
- NCT03676075
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Fudan University
Celiac Disease, Treatment Adherence
Use of a Home Test for Gluten Detection in Urine and Its Effect on Gluten-free Diet Adherence
The use of a home rapid test for the detection of gluten immunogenic peptides (GIP) in urine of treated adolescent patients with celiac disease (CD) could facilitate the adherence to the gluten-free diet (GFD) and contribute to…
- Conditions
- Celiac Disease, Treatment Adherence, Adolescent
- Trial name
- NCT05119322
- Testing
- GlutenDetect home urine test
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Biomedal S.L.
Heart Diseases, Cardiac Surgery
Evaluation of an AI-Based Lightweight ECG Telemetry Monitoring System
This study aims to evaluate the clinical applicability of the AI-based lightweight ECG monitoring system (MEMO Patch Plus) as a telemetry ECG monitoring system in patients undergoing cardiac surgery.
- Conditions
- Heart Diseases, Cardiac Surgery, Cardiac Arrhythmias
- Trial name
- NCT07725445
- Testing
- MEMO Patch
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- HUINNO Co., Ltd
Fever Malaria
Clinical Evaluation of the STANDARD™ Q Malaria/CRP Duo Test
The aim of this study is to assess the clinical performance (sensitivity, specificity, positive and negative predictive values) of the STANDARD™ Q Malaria/CRP Duo Test when used by health care workers (HW) in a point of care…
- Trial name
- NCT04791800
- Testing
- Malaria/CRP combination test
- Where
- India
- Volunteers
- 1,808 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Hepatocellular Carcinoma
Study of PIVKA-II and AFP Measurement in Surveillance Program for Early Detection of Hepatocellular Carcinoma
There is no prospective study on the test intervals of alpha-fetoprotein (AFP) or on the role of prothrombin induced vitamin K absence or antagonist-II (PIVKA-II) in surveillance program for early detection of hepatocellular…
- Trial name
- NCT01277653
- Testing
- tumor maker interval shortly
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Breast Cancer, Breast Cancer Female
SNAPS Breast Cancer Patient Study Breast Cancer Patients
Differential immunogenomic signatures from peripheral blood CD14 (phagocytic) and CD2 (non-phagocytic) cells have been associated with multiple cancers and disease states.
- Trial name
- NCT05370300
- Testing
- Blood test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Immunis.AI
Lymphoma
HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive Lymphoma
This is a study to use glucarpidase prophylactically to treat methotrexate induced toxicities in lymphoma patients with cerebral involvement.
- Trial name
- NCT04668768
- Testing
- Glucarpidase
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Fox Chase Cancer Center
Colorectal Cancer
Full-spectrum Endoscopy in Colorectal Cancer Screening
The purpose of this study is to compare the adenoma detection rates of full-spectrum endoscopy versus standard forward-viewing colonoscopy in colorectal cancer screening programme.
- Trial name
- NCT02812550
- Testing
- colonoscopy procedure
- Volunteers
- 249 people
- Sponsor
- Hospital del Rio Hortega
Colorectal Adenoma
Transparent Cap-Assisted Colonoscopy Combined With Computer-Aided Detection in Improving the Detection Rate of Colorectal Adenomas
A prospective, single-center, single-blind, randomized controlled study to compare the effectiveness of transparent cap-assisted colonoscopy combined with computer-aided detection and computer-aided detection alone in improvement…
- Trial name
- NCT07097350
- Testing
- computer-aided detection alone, transparent cap-assisted colonoscopy combined with computer-aided detection
- Where
- China
- Volunteers
- 524 people
- Sponsor
- Fudan University
Gastric Cancer
Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA
To facilitate the early gastric cancer diagnosis, an assay based on assessing large-scale methylation and fragmentation profiles of the plasma cell free (cfDNA) will be developed and validated.
- Trial name
- NCT05668910
- Testing
- whole genomic methylation and fragmentation profile analysis of cfDNA
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Colorectal Cancer, Adenoma
Comparing Detection of Standard Colonoscopy, CAD-EYE and Combined CAD-EYE and G-EYE® Aided Colonoscopy
The purpose of this study is to compare the additional diagnostic yield over Standard Colonoscopy (i.e., the adenoma miss-rate reduction) obtained by performing CADEYE and G-EYE® aided colonoscopy, vs.
- Trial name
- NCT05237310
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy, CAD-EYE
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Puerperal: [Major Infection] or [Sepsis]
Diagnostic Breath Analysis Study to Detect Sepsis
Analysis of exhaled breath samples using a high-speed gas chromatography medical device will identify Volatile Organic Compounds (VOC) that are specifically associated with SIRS and Sepsis.
- Trial name
- NCT02532959
- Testing
- Diagnostic Breath Analysis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Rectal Cancer, Lymph Node Metastasis
Radioisotope and Fluorescence Guidance in Rectal Cancer
A study to investigate if pelvic side wall lymph nodes that remain after neo-adjuvant chemoradiotherapy can be identified intraoperatively using dual radioisotope and fluorescence guidance.
- Trial name
- NCT05336643
- Testing
- Radiofluorescence
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Stroke
Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring
The purpose of this study is to assess whether repeated enhanced and prolonged ECG monitoring after ischemic stroke results in a higher detection of atrial fibrillation (/flutter) compared to usual care (at least 24 hour of…
- Trial name
- NCT01855035
- Testing
- prolonged ECG monitoring, standard care
- Where
- 4 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Cerebral Palsy, Prematurity
Study of Generalized Movements for Early Prediction of Cerebral Palsy
The purpose of this study is to assess the predictive value of generalized movements in preterm and term infants who are at risk for development of cerebral palsy.
- Trial name
- NCT00749008
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Charles R. Neal,
Knee Injuries
Deep Learning of Knee Joint MRI Intelligent Detection
Knee joint is the most common part of sports injury. MRI is a powerful tool to diagnose knee joint injury. However, it takes a long time to read the film, needs a lot, and some hidden injuries have a high rate of missed…
- Trial name
- NCT04958408
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Peking University Third Hospital
Liver Cancer
Diagnostic Accuracy of Folate-Targeted NIR-II Carbon Dots for Ex Vivo HCC Detection
This prospective, single-center observational study evaluates the diagnostic accuracy of a novel Folate-targeted Near-Infrared II Carbon Dot (FA-CDots) probe for the ex vivo assessment of Hepatocellular Carcinoma (HCC).
- Trial name
- NCT07295340
- Testing
- Ex Vivo FA-CDots Staining
- Where
- China
- Volunteers
- 20 people
- Sponsor
- West China Hospital
Metastatic Colorectal Cancer
Early Detection of Relapses in Stage IV Colorectal Cancer Patients
This study is a prospective, multicenter, observational study on metastatic, operable colorectal cancer to evaluate the proof of concept of the cfDNA analysis for the early detection of recurrences
- Trial name
- REDCLOUD (NCT04232891)
- Testing
- liquid biopsy
- Where
- 2 sites in Italy
- Volunteers
- 141 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Glomerulonephritis
US Time-Harmonic Elastography for the Early Detection of Childhood Glomerulonephritis
US Time-Harmonic Elastography for the Early Detection of Childhood Glomerulonephritis
- Trial name
- NCT04582890
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
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