Clinical trials: Development
Language Development, Literacy
Digital Literacy Promotion
This study evaluates the effects of digital versus standard literacy promotion, as well as dialogic language behaviors and reading comprehension among infants when comparing the use of e-books to standard board books.
- Trial name
- DLP (NCT03121365)
- Testing
- Digital/E-Book Arm, Standard/Board Book Arm
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sudden Infant Death
Incorporation of Safe Sleep Education Into m-Health Technology
Sudden Unexplained Infant Death (SUID) is the leading cause of death in infants age 28 days to 1 year. Protective factors, such as supine positioning, firm sleep surface, breastfeeding, pacifier use, elimination of soft objects…
- Trial name
- NCT06074211
- Testing
- Safety in Seconds mobile app: Safe Sleep Education, Safety in Seconds mobile app: Car Seat Safety Education
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Infant Development, Pain, Procedural
Parental Touch Trial (Petal)
This is a two centre two-arm randomised controlled interventional trial. We aim to determine whether parental touch prior to a painful clinical procedure provides effective analgesia in neonates.
- Conditions
- Infant Development, Pain, Procedural, Parents
- Trial name
- Petal (NCT04901611)
- Testing
- Parental touch
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Paediatric Neuroimaging Research Group
Unaccompanied Migration
Testing the Impact of Family-Based Intervention to Improve Developmental and Health Outcomes for Female Adolescents
This study seeks to address the urgent need for theoretically and empirically informed interventions that would address the increasing numbers of unaccompanied minors migrating from rural to urban centers in developing countries…
- Trial name
- NCT07278934
- Testing
- ANZANSI Family Program
- Where
- Ghana
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- New York University
Krabbe Disease
Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
This study is designed to learn about early brain development in children with Krabbe disease, and to use diffusion tensor imaging as an early diagnostic tool to identify newborns at risk for the disease.
- Trial name
- NCT00787865
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Molar Incisor Hypomineralization
Resin Infiltration Treatment Versus a Combined Treatment With Microabrasion for the Management of MIH Affected Incisors
The prevalence of molar incisor hypomineralization is relatively high. It has been reported that MIH-affected children experience a wide range of negative impacts because of having visible enamel opacities on their incisors…
- Trial name
- NCT04471571
- Testing
- Resin infiltration and microabrasion for MIH-affected incisors, Resin infiltration for MIH-affected incisors
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maternal Distress, Child Development
In Vitro Fertilization (IVF) and Prenatal Effects Independent of Genetics
This study examines how maternal stress during pregnancy affects infant brain and behavioral development, focusing on whether these effects are due to the prenatal environment or shared genes.
- Trial name
- NCT07296107
- Testing
- Prenatal maternal psychosocial and biological assessment protocol
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
Venous Thromboembolism
Efficacy of Sodium Heparin for Prophylaxis of Venous Thromboembolism in Surgical Patients
The aim of this study is to verify, through clinical examination and doppler, the non-inferiority of the drug test (heparin sodium 5.000UI/0.25 mL - HIPOLABOR) in relation to the drug compared (heparin sodium 5.000USP/mL - APP)…
- Trial name
- NCT00934167
- Testing
- heparin sodium - Hipolabor, Heparin sodium - APP
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
Behavior and Behavior Mechanisms
Translational Research to Inform Interventions for Challenging Behavior
This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts.
- Trial name
- NCT04842500
- Testing
- Demand Informed Moderator Analysis
- Where
- 5 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Elderly
Development of an Integrated Health Care Environment for Elderly With RFID Technology
A falling prevention system will be established by RFID location and motion detection. Using RFID to detect participants' allocation indoor.
- Trial name
- NCT00748683
- Testing
- RFID
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Birth Asphyxia, Neonatal Death
Development of a Mobile Application for HBB Prompt Study
This study applies an iterative user-centred design approach involving frontline birth attendants to create a mobile application ("HBB Prompt") to improve skills retention after initial newborn stabilization training through the…
- Trial name
- HBB-Prompt (NCT03577054)
- Testing
- HBB Prompt, Low-Dose High Frequency training
- Where
- Uganda
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Hepatitis B
Development of Read-outs in Healthy, Hepatitis B Virus Naive Adults Vaccinated With the Hepatitis B Surface Antigen (HBsAg) in Combination With a GlaxoSmithKline (GSK) Biologicals' Adjuvant System
This study aims to develop innovative immunological read-outs and new technologies in order to further characterise the early immune response and its kinetics as well as the adaptive immune responses to adjuvanted vaccines.
- Trial name
- NCT01777295
- Testing
- Adjuvanted Hepatitis B surface antigen (HBsAg) candidate vaccine GSK2231392A., EngerixTM-B
- Where
- Belgium
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Perinatal Depression, Parents
Supporting At-Risk Mothers Across Perinatal Period
The SMART app is a mobile application based psychosocial parenting intervention containing educational materials (articles, videos, audios, podcasts) on parenting, an integrated peer support chat function with experienced mothers…
- Conditions
- Perinatal Depression, Parents, Anxiety, Self Efficacy
- Trial name
- SMART (NCT06363019)
- Testing
- Supporting at-risk Mothers Across perinatal period: a Randomized controlled Trial (SMART) mobile application
- Where
- 2 sites in Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
PreDiabetes, Obesity
Development of an Adaptive Treatment for Weight Loss in People With Prediabetes
This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effective in people who are…
- Trial name
- NCT04745572
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Congenital Hypothyroidism, Hypothyroidism
Generic vs. Name-Brand Levothyroxine
This study compares two different brands of thyroxine (thyroid hormone). Currently, pharmacists may be substituting generic formulations of thyroid hormone without your doctor knowing about this.
- Trial name
- NCT00403390
- Testing
- Brand Name Levothyroxine (Synthroid), Generic formulation of Levothyroxine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pneumonia
Evaluation of Innovative Tools in Development of Antibiotics
The investigators will determine the difference of pharmacokinetics of ciprofloxacin and imipenem between healthy volunteers and intensive care patients suffering from pneumonia in plasma and at the target site - lung - using…
- Trial name
- NCT03177720
- Testing
- Ciprofloxacin, Imipenem
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Developmental Language Disorders, Developmental Articulation Disorder
Smart Computing Models, Sensors, and Early Diagnostic Speech and Language Deficiencies Indicators in Child Communication
This clinical trial aims to justify a protocol for designing and developing an automated decision-making system to support and enhance screening and early detection procedures for developmental speech/language difficulties in…
- Conditions
- Developmental Language Disorders, Developmental Articulation Disorder, Speech Disorder, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- SmartSpeech (NCT06633874)
- Testing
- TD Playing the Serious Game APSOU, Non-TD Playing Serious Game
- Where
- Greece
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Psychological
Developement and Validation of the Health Behavior Questionnaire Towards Deprescribing (HBQtD)
The goal of this observational study is to: 1. develop and validate a health behavior theory-based questionnaire to examine the older adults' and informal caregivers' determinants of deprescribing behavior 2.
- Trial name
- HBQtD (NCT06212713)
- Testing
- Questionnaire administration
- Where
- Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Short Stature
Weekly Zinc Chelate Supplementation on Children's Growth
The purpose of this study is to measure the effect of weekly zinc supplementation on schoolchildren with growth deficit or normal stature.
- Trial name
- APZinc (NCT01911260)
- Testing
- Zinc amino acid chelate
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Immunological Status, Healthy Volunteers
Critical Food Ingredients on Immunocompetence to Prevent the Risk and Development of Obesity/Metabolic Syndrome
Double-blind cross-over intervention where the volunteers were randomized into two groups who, after receiving nutritional counseling, received two formulations in the form of a cookie: Group 1, commercial formulation and Group…
- Conditions
- Immunological Status, Healthy Volunteers, Healthy Volunteers - Male and Female
- Trial name
- CricoImNut (NCT07496320)
- Testing
- Administration of a commercial cookie formulation, Immunonutritional_2
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMDEA Food