Clinical trials: Development Disorders
DSD, Hypospadias
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias).
- Trial name
- NCT06989593
- Testing
- Narrative Medicine Journaling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sarah Schlegel
Occupational Diseases, Work Related Upper Limb Disorder
ARPE Training for Manual Handling Workers: A Quasi-Experimental Study on Ergonomic Knowledge and Practice
The goal of this study is to evaluate whether an Augmented Reality-based ergonomic training module (ARPE) can improve ergonomic knowledge, self-prevention, and self-evaluation practices among adult manual material handling (MMH)…
- Trial name
- ARPE;MMH (NCT06993298)
- Testing
- Augmented Reality Ergonomics Training (ARPE), Conventional Ergonomics Training
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Growth, Vitamin D Supplementation
Next-generation Effects of Vitamin D Supplementation in Pregnancy
Vitamin D deficiency is common among pregnant women, despite daily vitamin D supplements. This study aims to investigate if maternal vitamin D intake of 90 vs 10 µg affects the overall health, growth, and immune system of the…
- Conditions
- Growth, Vitamin D Supplementation, Immune System Diseases, Child Development
- Trial name
- NCT05616117
- Testing
- Intrauterine 90µg D-vitamin, Intrauterine 10µg D-vitamin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gluten Intolerance
Development of a Celiac Safe Food Additive
The goal of this clinical trial was to investigate if intestinal deamidation of gliadin from wheat bread could be hindered by adding a E304i/zinc additive.
- Trial name
- NCT06005376
- Testing
- Breakfast rolls consisting of wheat flour with and without a E304i/zinc additive
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Vestibular Dysfunction, Dizziness
Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks
This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same…
- Conditions
- Vestibular Dysfunction, Dizziness, Falls (Accidents) in Old Age, Balance Assessment
- Trial name
- NCT07735078
- Testing
- Instrumented balance and gait assessment using wearable inertial sensors, Questionnaires and paper-based cognitive tests
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Axial Length, Myopia
China Children Eye Study
The primary objective of this multi-center, observational study is to establish the reference ranges of axial length in Chinese children and adolescents.
- Conditions
- Axial Length, Myopia, Child Development
- Trial name
- CCES (NCT05770661)
- Where
- 2 sites in China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Dementia Alzheimers
Dementia Risk Prediction Model: Development and Validation
At present, there is no treatment for dementia that changes the course of the disease. However, it is now understood that the proteins in dementias such as Alzheimer's disease are present years before someone develops symptoms of…
- Trial name
- NCT03943641
- Testing
- This is not an intervention study
- Where
- United Kingdom
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Developmental Language Disorder, Speech Sound Disorder
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04558541
- Testing
- Sensitivity to phonological rules, Sensitivity to semantic category cues.
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Hypertension
Evaluating the Relationship Between Inflammation, Genetics, and Stress in the Development of High Blood Pressure
High blood pressure affects nearly one third of all individuals in the United States. If left untreated, it can lead to stroke, heart failure, heart attack, kidney failure, or blindness.
- Trial name
- NCT00384241
- Testing
- Induced Stress, Buccal Swab
- Where
- United States
- Volunteers
- 1,099 people, healthy volunteers welcome
- Sponsor
- Augusta University
Bladder Cancer
Development of a Non-Invasive DNA Methylation-Based Assay System for the Risk Assessment of Urothelial Carcinoma
Bladder cancer ranks the ninth in worldwide cancer incidence. Approximate 90% of bladder cancer is the malignancy of urothelium tissues, the urothelial cancer (UC).
- Trial name
- NCT00867620
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Telehealth Autism Assessment for Adults
The study aims to investigate the reliability and validity of an adapted Autism Spectrum Disorder assessment measure for use in a telehealth visit.
- Trial name
- NCT04766970
- Testing
- ADOS-2 Module 4, Adapted Telehealth ADOS-2 Module 4
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism, Asperger's Syndrome
Functional Magnetic Resonance Imaging (fMRI) for the Study of Response Inhibition, and Face and Linguistic Processing in Autism
This study investigates face processing, response inhibition and phoneme processing in autistic adults by fMRI.
- Trial name
- NCT00211783
- Testing
- fMRI
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pancreas Cancer, Diagnosis
Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine
This study aim to develope a diagnostic method of pancreatic cancer by using a reagent for analyzing purine metabolite (Hypoxanthine, Xanthine) in urine. It is safe and cost effective compare to radiologic or blood test.
- Trial name
- NCT06291779
- Testing
- Purine metabolite (Hypoxanthine, Xanthine) in urine by CubeBio
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ho-Seong Han
Obesity, Growth Hormone
Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity
Obesity is one of the leading causes of cardiovascular-related diseases, including diabetes and heart disease. Obesity, and more specifically abdominal obesity, may cause decreased growth hormone (GH) levels.
- Trial name
- NCT00562796
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Diseases in Children
NICE - Nutritional Impact on Immunological Maturation During Childhood in Relation to the Environment
Role of the exposome on allergy, caries, and neurophysiological development in childhood.
- Trial name
- NICE (NCT05809479)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 1,950 people, healthy volunteers welcome
- Sponsor
- Umeå University
Behavior Problem, Development Delay
Norwalk Feasibility Study
The purpose of this study is two-fold: 1) to examine the feasibility of the Drop-In model of Family Nurture Intervention (FNI); and 2) to collect pilot data concerning the mother's response to the Drop-In model of FNI and short…
- Conditions
- Behavior Problem, Development Delay, Emotional Disturbances, Family Conflict
- Trial name
- NCT04048720
- Testing
- Family Nurture Intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Mental Health Disorder, Mental Health Impairment
Youth FORWARD Phase 1 YRI and EPP Study
Objectives: The objectives of this research proposal are to study the delivery of an evidence-based mental health intervention in the alternate setting of youth employment programs tied to regional economic development and to…
- Conditions
- Mental Health Disorder, Mental Health Impairment, Psychosocial Impairment, Emotional Dysfunction
- Trial name
- NCT03603613
- Testing
- YRI, EPP
- Where
- Sierra Leone
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston College
Healthy Individuals
Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes
There are controversial data about fluoride intake by children when tooth brushing with children's or regular toothpastes. However, a study have showed that children were exposed to a dose of 0.051 mg F/Kg/day and 0.046 mg…
- Trial name
- F (NCT01568541)
- Testing
- Regular toothpastes, Children's toothpastes
- Where
- 3 sites in Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Autism Spectrum Disorder, Executive Functioning
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings.
- Trial name
- NCT06651086
- Testing
- Unstuck and On Target, Unified Protocol for Children
- Where
- 2 sites in United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Arthritis, Spondylitis, Ankylosing
Natural History and Development of Spondyloarthritis
Background: Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal bone growth affecting the joints and spine.
- Trial name
- NCT01422694
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
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