Clinical trials: Development Disorders
Fragile X Syndrome, Angelman Syndrome
Parent and Infant Inter(X)Action Intervention (PIXI)
The objective is to develop and test, through an iterative process, an intervention to address and support the development of infants with a confirmed diagnosis of a neurogenetic disorder with associated developmental delays or…
- Conditions
- Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Dup15Q Syndrome
- Trial name
- NCT03836300
- Testing
- Parent-Infant Inter(X)action Intervention (PIXI)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RTI International
Infant Malnutrition, Nutrition Knowledge
Improving the Nutrition Status of Infants in South-Western Uganda
Undernutrition and growth restriction due to poor diet and inadequate nutrient intake continues to be a global challenge, particularly in the developing countries including Uganda.
- Conditions
- Infant Malnutrition, Nutrition Knowledge, Growth, Cognitive Development
- Trial name
- CHNUDEV (NCT02098031)
- Testing
- Improving nutrition knowledge among mothers
- Where
- Uganda
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Radiologically Isolated Syndrome, Epstein-Barr Virus Infections
Environmental Risk Factors in Multiple Sclerosis Development: Epidemiological Study of EBV Infection and Vitamin D Deficiency in RIS Patients
This is an ancillary study using samples collected in the ProBioRIS cohort (NCT06395662). The aim of the project is to highlight new biomarker candidates to assess the risk of conversion to clinically definite multiple sclerosis…
- Trial name
- RIS - EBVD (NCT07256431)
- Testing
- Antibiody titration
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypotonia-Cystinuria Syndrome, Muscle Hypotonia
PREPL in Health and Disease
Evaluation of PREPL activity in healthy controls and known or possible PREPL deficient patients
- Conditions
- Hypotonia-Cystinuria Syndrome, Muscle Hypotonia, Healthy Volunteers, Dwarfism, Growth Hormone Deficiency
- Trial name
- PHD (NCT02263781)
- Testing
- Blood draw, muscle biopsy
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson's Disease
Development of a Face Valid Executive Functioning Task
The purpose of this study is to develop a task to measure executive thinking skills that can be performed in a laboratory setting, but has clear parallels to the thinking demands of real life situations, and can be administered…
- Trial name
- MedTask (NCT00918112)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gastric Cancer, Tongue Images
Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms
In this study, the investigators will prospectively recruit 100,000 individuals, including gastric cancer patients who have not undergone any anti-tumor treatment and non-gastric cancer participants.
- Conditions
- Gastric Cancer, Tongue Images, Diagnosis
- Trial name
- NCT06078930
- Testing
- Tongue imaging, tougue coating, saliva, gastric juice, and feces
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang Cancer Hospital
Type 1 Diabetes Mellitus, Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome in Type 1 Diabetes
BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary syndrome (PCOS), is very prevalent in women with type 1 diabetes (T1D). The pathogenic mechanisms of this association remain unclear.
- Trial name
- NCT07490964
- Testing
- Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Mental and Behavioral Disorders, Mental Resilience
Media and Mental Health
This study's goal is to find if using the ThinkHumanTV program during 6 weekly sessions of watching Netflix or Disney series or movies for 90 minutes, together with 4 - 8 members of the Whole Health Center and EpiCenter and a…
- Conditions
- Mental and Behavioral Disorders, Mental Resilience, Emotional Awareness, Emotional Development
- Trial name
- NCT07286305
- Testing
- ThinkHumanTV
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Autism Spectrum Disorder
Relationships, Employment, Autonomy, and Life Satisfaction (REALS) Study
One of the major methodological obstacles to more informed policies and programs to support the successful transition to adulthood in autism spectrum disorder (ASD) is the absence of suitable measures of meaningful outcomes for…
- Trial name
- REALS (NCT04381195)
- Testing
- REALS Development, REALS Testing
- Where
- United States
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorders
Parents Workgroup About Emotion Regulation
The purpose of this study is examine emotional regulation and reflective functioning in parents of children with Autism Spectrum Disorders (ASD) before and after an educational training (four sessions of group workshops).
- Trial name
- NCT02400177
- Testing
- emotion regulation training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Premature Birth
Studying Newborns' Brain Activity in the NICU Through a Musical Intervention: the Role of Fundamental Frequency
This research project stands to the intersection of neonatology, neuroscience, and music based interventions (MBIs), exploring the impact of structured sound on the brain activity of premature newborns in Neonatal Intensive Care…
- Trial name
- FunFreqNICU (NCT06398912)
- Testing
- Music Based Intervention
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
HIV Infections, Sexually Transmitted Infections (Not HIV or Hepatitis)
Developing an HIV Disclosure Intervention for Men in Uganda
The goal of this clinical trial is to test an HIV disclosure intervention that the investigators are developing focused on men living with HIV in Uganda.
- Trial name
- DASH (NCT05771519)
- Testing
- HIV disclosure intervention
- Where
- Uganda
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Foetal Differences Between Healthy and Schizophernic Parents
Schizophrenia Imaging
Schizophrenia is a common disorder with a lifetime prevalence of about 1%.Genetic studies strongly suggest a genetic component to the inheritance of schizophrenia.
- Trial name
- NCT01655472
- Testing
- imaging follow up: MRI scan, imaging follow up: Ultrasonographic examination
- Where
- 8 sites in Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Overweight, Physical Activity
The Healthy Elementary School of the Future
Unhealthy lifestyles in early childhood are a major global health challenge. These lifestyles often persist from generation to generation and contribute to a vicious cycle of health-related and social problems.
- Conditions
- Overweight, Physical Activity, Malnutrition, Child Development
- Trial name
- THESF (NCT02800616)
- Testing
- The Healthy Primary School of the Future, The Physical Activity School
- Volunteers
- 2,349 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Dental Trauma, Enamel Hypoplasia
Evaluation of Sequelae in Permanent Successors Following Traumatic Injuries to Primary Teeth
Retrospective data analysis of children with primary dental trauma and follow-up visual examination to find out the sequelae.
- Conditions
- Dental Trauma, Enamel Hypoplasia, Sequelae, Sequelae Successors
- Trial name
- NCT07134348
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Zeynep Aslı GÜÇLÜ
Uterine Cervical Neoplasms
AI Model for Cervical Cancer Detection From Colposcopy Images
Cervical cancer is a significant health issue, particularly in low-income countries, where late diagnosis and limited access to screenings contribute to high mortality rates.
- Trial name
- NCT06644248
- Testing
- Colposcopy
- Where
- Bangladesh
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bangladesh University of Engineering and Technology
Arterial Hypertension
Arterial Hypertension in Men in the Warmia and Masuria Region
The primary aim of the study is to define the prevalence of arterial hypertension and risk factors of its development in an unselected group of Polish men from the region of Warmia and Mazury, considered as one of the most…
- Trial name
- ProM (NCT03559608)
- Where
- Poland
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury
Alzheimer's Disease
Valproic Acid in Subjects With Intact Cognition - Proof of Concept Study
The purpose of this study is to evaluate the safety of administration and effects of valproic acid on clusterin expression in cognitively-intact, healthy, elderly subjects.
- Trial name
- VPA (NCT01729598)
- Testing
- Valproic Acid
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gregory Jicha, 323-5550
Obesity, Overweight
Early Stockholm Obesity Prevention Program
To study whether a targeted intervention can prevent the development of overweight and obesity among pre-school children in families with either one obese or two overweight parents.
- Trial name
- EarlySTOPP (NCT01198847)
- Testing
- Dietary, physical activity and sleeping
- Where
- Sweden
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Abdominal Diseases
Rapid Abdominal Diagnosis With AI & Radiology
This study aims to develop an AI-assisted diagnostic system for abdominal contrast-enhanced CT images using data from multiple inpatient centers.
- Trial name
- RADAR (NCT07040358)
- Where
- China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
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