Clinical trials: Development Disorders
Intellectual Disability
Development and Application-Smart Football for Movement Evaluation and Training in the Special Education Population
Children with disabilities are frequently ignored by the general population, hence the development of movement evaluation and training devices for use in special education settings are relatively overlooked.
- Trial name
- NCT02486081
- Testing
- smart soccer ball
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dementia
Development and Effectiveness of a User-centered Mobile Application for Informal Caregivers of People Living With Dementia: Randomized Controlled Trial
The research shows that the mobile application developed for informal caregivers of people living with dementia affects caregivers' care burden, quality of life; It was planned as a mixed-type, randomized controlled study to…
- Trial name
- NCT06179667
- Testing
- Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Neurodevelopmental Disorders
Positive Emotion Regulation Training in Children, Adolescents and Young Adults With and Without Developmental Disorder
The purpose of this study is to evaluate the efficacy of a novel positive emotion regulation intervention that aims to increase positive emotions and improve emotion regulation skills in children, adolescents and young adults.
- Trial name
- ERICA (NCT02898298)
- Testing
- Positive Emotion Regulation Training
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Pectus Carinatum, Chondromanubrial
Chest Compressor for Conservative Treatment of Pectus Carinatum: a Multicenter Study
Pectus carinatum (PC) is a congenital deformity of the chest wall whose prevalence is 0.6% of the population and although it does not cause cardio respiratory physiological damage, it has profound psychological effects on young…
- Trial name
- NCT04171063
- Testing
- Thoracic compressor
- Where
- 4 sites in Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Fluorosis
Clinical Evaluation of Different Minimal Invasive Treatment Modalities of Mild to Moderate Dental Fluorosis Using A Visual Analog Scale
This study was conducted for clinical evaluation of the quality of different minimal-invasive treatment modalities and combination treatments in esthetics improvement of mild to moderate fluorosed teeth using two different…
- Trial name
- NCT05051748
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Autism Spectrum Disorder (ASD), Intellectual Disability
Emotion Intensity Modulates Intention in ASD
This study used eye-tracking to examine how emotional expression intensity (low/medium/high) influences intention understanding in children with ASD, PDD, and TD during a puzzle-search task.
- Trial name
- NCT07597655
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Amelogenesis Imperfecta
Oral Health Related Quality of Life of Children With Amelogenesis Imperfecta
This project aims to evaluate the impact of anterior veneer treatment on oral health-related quality of life in children with amelogenesis imperfecta (AI).
- Trial name
- NCT07250906
- Testing
- Veneers
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Alcoholism
Validation of a Test System for Development of Medications for Alcoholism
Using theTEMA (test system for development of medications for alcoholism) it can be shown, that naltrexone administration reduces the willingness to perform work for alcohol infusion in a laboratory experiment.
- Trial name
- TEMANX (NCT02652585)
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Autism Spectrum Disorder, Parental Stress
The Effect of a Micro-Appreciation Intervention (Three-Things Journal Application) on Caregiver Burden, Family Functioning, and Happiness Levels for Mothers of Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder in which individuals experience significant difficulties in social interaction, communication, and repetitive behaviors.
- Trial name
- NCT07124091
- Testing
- Positive Event Writing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Infertility
Results Following the Vitrification of Human Oocytes Using 2 Methodologies
The investigators are going to compare embryo developmental rates of human eggs following freezing in two different freezing methods.
- Trial name
- NCT01033474
- Where
- Peru
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwest Center for Reproductive Sciences
Cockayne Syndrome
Metabolic Study of Cockayne Syndrome
Cockayne syndrome (CS) is related to defective DNA transcription and/or repair and belongs to the family of Nucleotide Excision Repair.
- Trial name
- METABO-CS (NCT03044210)
- Testing
- Metabolic evaluation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Overweight, Obesity
Fatty Acids During Pregnancy and Lactation and Body Fat Mass in Newborns
Pregnant and lactating women receive n-3 fatty acids starting from week 15 of gestation until 4 months post-partum (pp) in comparison to a control group, who only gets information about adequately healthy nutrition during…
- Trial name
- NCT00362089
- Testing
- Marinol D-40
- Where
- Germany
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Cytochrome P450 Oxidoreductase Deficiency, Hypertension
Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency
This study investigates the etiology of hypertension and endothelial damage in patients with Cytochrome P450 Oxidoreductase (POR) deficiency.
- Conditions
- Cytochrome P450 Oxidoreductase Deficiency, Hypertension, Endothelial Dysfunction, Congenital Adrenal Hyperplasia
- Trial name
- PORENDO (NCT06756620)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ozge Bayrak Demirel
Autism
Show Me to Help Me
This cohort observation, randomized controlled trial is intended to provide data that icons and non-verbal communication improve communication and cooperation with children with Autism/communication delay and aid in the…
- Trial name
- NCT01311596
- Testing
- Icons
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Autism Spectrum Disorder, Parenting Self-efficacy
Multicomponent Group Parent Program Incorporating Naturalistic Teaching in Türkiye
This randomized study examined a 10-session multicomponent group parent program incorporating Naturalistic Teaching principles for caregivers of autistic children enrolled in preschool or early intervention services in Türkiye.
- Trial name
- NCT07416903
- Testing
- Multicomponent Group Parent Program Incorporating Naturalistic Teaching, General Parenting Comparison Seminar
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Lung Cancer
Lung EpiCheck Biomarkers Development Study
This study is part of the development of a non-invasive lung cancer screening test which aim to identify early-stage lung cancer in patients at high risk for lung cancer.
- Trial name
- NCT06245876
- Testing
- Blood collection
- Where
- 10 sites in United States, Hungary and 2 more
- Volunteers
- 2,132 people, healthy volunteers welcome
- Sponsor
- Nucleix Ltd.
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
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