Clinical trials: Development Disorders
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Gastric Cancer, Gastritis, Atrophic
Gastric Cancer Screening Quality Improvement System Establishment
Experienced endoscopists will perform endoscopy during the study period and the detection rate of gastric premalignant lesion, correlation between endoscopic and serologic diagnosis of premalignant lesions and inter-observer…
- Conditions
- Gastric Cancer, Gastritis, Atrophic, Intestinal Metaplasia
- Trial name
- NCT02457624
- Testing
- Education and feedback
- Where
- South Korea
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Congenital Heart Diseases, Children
Physical Activity and Cognitive Development in Children
1. Compare physical activity and cognitive functions between children having cardiac surgery with an age-matched group of children undergoing non-cardiac surgery, as well as otherwise healthy siblings or best buddies (or age and…
- Trial name
- NCT02542683
- Testing
- structured physical activity program
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Columbia University
Autistic Disorder
Social Skills in Children With ASD and Process Drama
This is a one-group, pre-post feasibility study of an intensive, interdisciplinary (theatre, Occupational Therapy (OT), and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT02850666
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Utah
Atrial Fibrillation, Heart Failure
A CALIBER Study: Risk Factors for Stroke, Heart Failure, and Myocardial Infarction in Atrial Fibrillation
We aim to investigate the prognosis of patients diagnosed with AF, particularly in relation to the development of subsequent stroke, heart failure, and myocardial infarction.
- Conditions
- Atrial Fibrillation, Heart Failure, Stroke, Myocardial Infarction
- Trial name
- NCT01944397
- Where
- United Kingdom
- Volunteers
- 125,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Molar-Incisor Hypomineralisation
Silver Diamine Fluoride in Molar-Incisor Hypomineralisation
The objective of this study is to assess the efficacy of silver diamine fluoride application in molars affected by molar-incisor hypomineralization.
- Trial name
- NCT06165042
- Testing
- glass hybrid restorative system, Fluoride varnish + Glass hybrid restorative system
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Marmara University
Autistic Disorder
Associative Memory in Adults With an Autism Spectrum Disorder
The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity.
- Trial name
- MEM-T2A (NCT02279680)
- Testing
- Electroencephalography, Neuropsychological assesments
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Parenting, Development, Child
Pathways for Parents After Incarceration Feasibility Study
The purpose of this study is to learn how to better support fathers and their families after incarceration. It will test an intervention that promotes healthy development for children of previously incarcerated fathers and the…
- Conditions
- Parenting, Development, Child, Behavior
- Trial name
- NCT04525703
- Testing
- Pathways for Parents after Incarceration
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cognitive Dysfunction, Cognitive Disorder
Effects of Video Games and Ball Tossing on Eye Hand Coordination in Elderly With Mild Cognitive Impairment.
One of the key challenges faced by individuals with mild cognitive impairment (MCI) is the decline in cognitive and motor abilities, particularly eye-hand coordination (EHC), which is essential for performing daily activities and…
- Conditions
- Cognitive Dysfunction, Cognitive Disorder, Cognitive Decline
- Trial name
- NCT07182396
- Testing
- Experimental Group, Control Group
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Preterm Birth, Neurodevelopment
Preterm Birth Cohort Study in Guangzhou
The Preterm Birth Cohort Study in Guangzhou (PBCSG) aims to explore the impact of genetic and environmental factors including life styles on preterm birth, to examine the interaction effect between these factors, and to follow up…
- Conditions
- Preterm Birth, Neurodevelopment, Immune Development, Host and Microbiome
- Trial name
- PBCSG (NCT03668327)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Breast Masses, Breast Cancer
Photoacoustic/Ultrasound Imaging for Breast Nodule Diagnosis, Molecular Classification, and Neoadjuvant Chemotherapy Response Evaluation
Photoacoustic (PA) imaging (PAI) emergerd as a rapidly evolving biomedical imaging modality, which combines the merits of optical imaging and ultrasound (US) imaging, and has a capacity in morphological, functional and molecular…
- Conditions
- Breast Masses, Breast Cancer, Breast Cancer Treated with Neoadjuvant Chemotherapy
- Trial name
- NCT06908291
- Testing
- Multi-modal photoacoustic/ultrasonic (PA/US) imaging system
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Parkinson Disease, Huntington Disease
A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
Measurement of metabotropic glutamate receptor type 5 (mGluR5) binding capacity in the brain, may be a valuable tool in the early detection, understanding, or evaluation of Parkinson disease (PD), Huntington disease (HD), Fragile…
- Conditions
- Parkinson Disease, Huntington Disease, Autistic Spectrum Disorders, Fragile X Syndrome
- Trial name
- FPEB (NCT00870974)
- Testing
- [18F]FPEB
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II
Addressing Barriers to Palliative Care Use in Bladder Cancer
Investigators plan to establish an in-depth understanding of knowledge and beliefs about palliative care in advanced Bladder Cancer patients and their caregivers, and to identify factors associated with positive and negative…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II, Bladder Cancer Stage III, Bladder Cancer Stage IV
- Trial name
- NCT04598724
- Testing
- Surveys
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Autism Spectrum Disorder
The Effect of Mindfulness-Based Self-Compassion Education Given to Parents of Children With Autism Spectrum Disorder
Autistic Spectrum Disorder (ASD) is an important public health problem in our country as well as all over the world. The physical, psychological, social and economic problems and mood disorders experienced by the parents of these…
- Trial name
- NCT05693662
- Testing
- Session 1, Session 2, Session 3
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Primary Glaucoma, Glaucoma Suspect
Development of the Glaucoma Visual Functioning Questionnaire-40 and Its Psychometric Properties
The objective of this study is to develop and test the psychometric properties of a self-report questionaire, the Glaucoma Visual Functioning Questionnaire-40 (GVFQ-40), which was designed to measure the difficulty of daily…
- Trial name
- NCT04722861
- Testing
- GVFQ-40
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Molar Incisor Hypomineralization
Restorative Treatment in First Molars Affected by Molar-Incisor Hypomineralization
The restorative management of molars with Molar-Incisor Hypomineralization (MIH) represents a challenge in the clinical practice with high failure rate.
- Trial name
- NCT02717286
- Testing
- restorative
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Paraná
Maternal-Fetal Relations, Microcephaly
Fetal and Maternal Head Circumference During Pregnancy in Israeli Population
In this study, measurements of fetal and maternal head circumference will be collected. This data will be presented in table or graph form.
- Trial name
- NCT02510170
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Autism Spectrum Disorder
Social Cognitive Development in Young Children With Autism
Through the development of a novel treatment targeting core Autism Spectrum Disorder (ASD) social deficits and studying the efficacy of this intervention, the investigators hope to provide a means for children with ASD to more…
- Trial name
- NCT01425918
- Testing
- Social Enhancement Intervention, Parent Education
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
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