Clinical trials: Development Disorders
Opioid Use Disorder
Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine
This study aims to develop and pilot test a patient decision aid (PtDA) for emergency department (ED)-initiated buprenorphine treatment for opioid use disorder (OUD).
- Trial name
- NCT07278518
- Testing
- Patient Decision Aid for Opioid Use Disorder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Pregnancy Related, Pregnancy Disease
Chinese Pregnant Woman Cohort Study (Offspring Follow-up)
Purpose: To investigate the growth and development status for children of 1 ~ 3 years old in China, and to explore and analyze the influencing factors of infant growth.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy, Infant Development
- Trial name
- NCT04444791
- Where
- China
- Volunteers
- 1,978 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Frailty, Oncology
Approaches and Metrics in Fraily Patients During COVID-19 Era
The COVID-19 pandemic started in December 2019 in Wuhan, the Chinese province of Hubei. Compared to the period of the first epidemic wave (March to May 2020), in the period of the second epidemic wave (October 2020 to July 2021)…
- Conditions
- Frailty, Oncology, Immune Deficiency
- Trial name
- COMETA (NCT05792891)
- Testing
- Collecting biological material from frail patients, with or without COVID-19
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Chronic Pain, Musculoskeletal Pain
Video Intervention for Older Adults With Chronic Pain
Chronic musculoskeletal (MSK) pain, which includes spinal pain, osteoarthritis, and fibromyalgia, is a common and costly problem for older adults and is associated with decreased quality of life.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Older Adults With Chronic Pain
- Trial name
- NCT07404618
- Testing
- Reclaim Your Day, Health education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Butler Hospital
Human Microbiome, Pediatrics
Human Microbiome Research and Development for Overcoming Pediatric Diseases
Prediction and treatment of pediatric diseases and long-term outcomes through microbiome and multi-omics analysis by life cycle: We aim to demonstrate that a wide range of diseases are associated with gut microbiome dysbiosis and…
- Conditions
- Human Microbiome, Pediatrics, Disease, Growth & Development
- Trial name
- NCT06812091
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Colorectal Neoplasms
European Serrated Adenoma Classification Score
The aim of the study is to develop a score system in order to differentiate adenomatous polyps, hyperplastic polyps and serrated adenomas on the basis of optical features.
- Trial name
- ESCO (NCT03486418)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Achondroplasia
An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia
The intent and design of this Phase 3 study is to assess BMN 111 as a therapeutic option for the treatment of children with Achondroplasia
- Trial name
- NCT03424018
- Testing
- BMN 111
- Where
- 24 sites in United States, Australia and 5 more
- Volunteers
- 119 people
- Sponsor
- BioMarin Pharmaceutical
Achondroplasia
Lifetime Impact of Achondroplasia Study in Europe-LIAISE
Observational study looking at the burden of illness in achondroplasia subjects aged 5-70. The study will include a 5 year review of historical clinical data as well as a single point collection of questionnaire data to look at…
- Trial name
- LIAISE (NCT03449368)
- Where
- 13 sites in Austria, Denmark and 4 more
- Volunteers
- 196 people
- Sponsor
- BioMarin Pharmaceutical
Bone Aging, Osteoporosis Diagnosis
Automated Bone Age Estimation From Noncontrast Abdominal CT Using Deep Learning
This study is a retrospective analysis that uses abdominal CT scans, which were originally taken for other medical reasons, to estimate bone age.
- Trial name
- NCT07162168
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Fibromyalgia
Prehabilitation for Being Active. A Feasibility Study in Fibromyalgia
Twelve people with FM will be recruited from the FM patient support groups. The investigators will develop and test a 4-week prehabilitation educational programme (i.e., a behavioural change intervention) consisting of meeting…
- Trial name
- NCT03764397
- Testing
- Prehabilitation for behavioural change
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Universidad de Granada
Premature Birth, Psychological Stress
Parental Stress and Attachment in Preterm Infants
Introduction: Advances in neonatology mean a significant reduction in mortality in premature infants as well as an increase in the risk of morbidity in the medium, short and long term.
- Conditions
- Premature Birth, Psychological Stress, Physiological Stress
- Trial name
- NCT06813560
- Testing
- hair cortisol, salivary cortisol, salivary Oxytocin
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Growth Hormone Deficiency
A Multi-Dose Study to Assess Tolerability, Safety and Pharmacology of hGH-ViaDerm™ System in Adults With GH-Deficiency
This study aims to examine the safety, tolerability and pharmacokinetics of transdermal delivery of human Growth Hormone (hGH or somatropin) using the ViaDerm device in adult patients with Growth Hormone Deficiency Syndrome.
- Trial name
- NCT00455260
- Testing
- hGH-ViaDerm™ System (hGH or somatropin), hGH-ViaDerm™ System
- Volunteers
- 60 people
- Sponsor
- Teva Neuroscience, Inc.
Marfan Syndrome
Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients
The major clinical problems in patients with Marfan Syndrome (MFS) are aortic root dilation (ARD), dissection and rupture. Although the available treatments (beta-blockers, BBs) improve the evolution of the disease, they do not…
- Trial name
- MaNeLo (NCT00683124)
- Testing
- Losartan and nebivolol, Losartan, Nebivolol
- Where
- Italy
- Volunteers
- 291 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Neurological Rehabilitation, Stroke
Effects of Repetitive Transcranial Magnetic Stimulation Therapy on Lower Extremity Motor Development in Stroke Patients
The aim of our study is to investigate the effects of rTMS applications at different current frequencies (low frequency / intermittent (intermittent) theta burst (iTBS)) in stroke patients on lower extremity motor development…
- Conditions
- Neurological Rehabilitation, Stroke, Lower Extremity Problem, Quality of Life
- Trial name
- NCT05554861
- Testing
- Low Frequency rTMS Protocol, Intermittent Theta Burst Stimulation (iTBS) Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Autism
Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism
This study will evaluate the effectiveness of atomoxetine in treating children with attention deficit hyperactivity disorder symptoms associated with autistic disorder, Asperger's syndrome, and pervasive developmental disorder…
- Trial name
- NCT00498173
- Testing
- Atomoxetine
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Growth Hormone Deficiency
Safety Study of Syntropin (Human Growth Hormone) for the Treatment of Growth Hormone Deficiency
The purpose of this study is to evaluate the pharmacokinetics of Syntropin (a human growth hormone) and to determine the serum concentration of IGF-1 after Syntropin injection.
- Trial name
- NCT00489294
- Testing
- Syntropin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Phage Pharmaceuticals, Inc.
Alcohol Consumption, Alcohol Use Disorder
Step Away: Comparing a Chatbot-delivered Alcohol Intervention With a Smartphone App
A wide gap exists between the number of people needing alcohol treatment and those actually receiving it. This study builds on a previous one that indicated that smartphone-based intervention can help increase the number of…
- Trial name
- NCT04447794
- Testing
- Step Away Chatbot, Step Away App
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Depression, Anxiety
BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD)
Many youth with disabilities and their families receive "care coordination services" from a state Maternal and Child Health Bureau (MCHB) agency.
- Conditions
- Depression, Anxiety, Transition
- Trial name
- BEST (NCT05520983)
- Testing
- Adapted Teens Achieving Mastery over Stress (TEAMS) Treatment, Adapted Teens Achieving Mastery over Stress (TEAMS) Prevention, Adapted Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT)
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Gastrointestinal Problems, Autism Spectrum Disorders
Beneficial Bacteria Treatment for Autism
This is an open-label clinical trial to investigate a combination therapy for treating gastrointestinal problems in children with autism spectrum disorders. The combination therapy includes beneficial bacteria.
- Trial name
- BBT (NCT02504554)
- Testing
- oral Vancomycin, MoviPrep, Prilosec
- Volunteers
- 18 people
- Sponsor
- Arizona State University
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