Clinical trials: Development Disorders, open to volunteers
Cortical Excitability, Brain Stimulation
Cortical Excitability and Role of Non Invasive Brain Stimulation in ADHD and AUTISM
This double-blind, randomized, sham-controlled clinical trial will evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on children and adolescents with attention-deficit/hyperactivity disorder (ADHD) or…
- Conditions
- Cortical Excitability, Brain Stimulation, ADHD, Autism
- Trial name
- NCT07315217
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with adult growth hormone deficiency (AGHD) and mild…
- Trial name
- GRIT (NCT04867317)
- Testing
- Somatropin
- Where
- 16 sites in United States
- Volunteers
- 172 people
- Sponsor
- VA Office of Research and Development
Dysphagia Following Cerebrovascular Accident
Evaluation of Effectiveness of an Interactive Dysphagia Education System for Patients With Stroke
The goal of this clinical trial is to learn if an interactive dysphagia education system can improve swallowing outcomes and quality of life in patients with post-stroke dysphagia.
- Trial name
- NCT07810374
- Testing
- Interactive dysphagia education
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Mei-Yu Lin
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Family Conflict, Marital Conflict
Families of Youth with Developmental Disabilities: a Theory-Based Intervention
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability.
- Conditions
- Family Conflict, Marital Conflict, Communication
- Trial name
- NCT03495440
- Testing
- Center Sessions, At-home
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Asthma
Therapeutic Relevance of Abnormal Airway Morphology in Asthma
Most individuals with asthma can effectively manage their symptoms and maintain normal lung function using inhaled medications, unfortunately, there is a subset of asthma sufferers whose symptoms, lung function, and risk of…
- Trial name
- AirPATH (NCT06970080)
- Testing
- Inhaled corticosteroid (ICS), Oral Corticosteroid (OCS)
- Where
- 2 sites in Canada
- Volunteers
- 242 people
- Sponsor
- McMaster University
Vitamin D 25-Hydroxylase Deficiency, Undernutrition
Impact of Trout Fish, Cow Milk With Egg, Vitamin D Supplementation, and Dietary Education on Vitamin D Status, Undernutrition, and Neurocognitive Outcomes Among School Children in Pakistan: An Open-label Individually Randomized Controlled Trial
Vitamin D deficiency and undernutrition are major public health concerns globally, particularly among children in low-resource and high-altitude settings.
- Conditions
- Vitamin D 25-Hydroxylase Deficiency, Undernutrition, Neurocognitive Development
- Trial name
- NCT07864662
- Testing
- Vitamin D supplement 4000 IU weekly, 200 grams of cooked trout fish, 250 milliliters of whole cow milk + whole egg
- Where
- Pakistan
- Volunteers
- 304 people
- Sponsor
- Aga Khan University
Snake Bite
Multicenter Application Verification and Effect Evaluation of Artificial Intelligence-Based Snake Species Identification System in the Diagnosis and Treatment of Snakebites
This multicenter prospective observational study aims to develop and validate a deep learning-based artificial intelligence snake species identification system, and evaluate its clinical application efficacy in real-world…
- Trial name
- NCT07658885
- Testing
- SSRS system-assisted snake species identification
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Huntington's Disease
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable…
- Trial name
- HDClarity (NCT02855476)
- Where
- 40 sites in United States, Canada and 8 more
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University College, London
Sarcoidosis, Pulmonary
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
- Trial name
- RISE-UP (NCT05567133)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Immunity, Respiratory Infection
Childhood Infection and Immunity Longitudinal Cohort
This prospective observational study will enroll approximately 1,200 children from birth through 7 years of age in Zhejiang Province, China.
- Conditions
- Immunity, Respiratory Infection, Asthma
- Trial name
- NCT07815925
- Where
- 2 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Cystic Fibrosis, Immunologic Deficiency Syndrome
Natural History of Noncirrhotic Portal Hypertension
Background: Noncirrhotic Portal Hypertension (NCPH) is caused by liver diseases that increase pressure in the blood vessels of the liver. It seems to start slowly and not have many warning signs.
- Conditions
- Cystic Fibrosis, Immunologic Deficiency Syndrome, Turner Syndrome, Congenital Hepatic Fibrosis
- Trial name
- NCT02417740
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gait
Dual-tasking Effect on Gait in Children With Developmental Coordination Disorder
The aim of the study is to collect data in children with developmental coordination disorder (DCD) aged between 7 and 17 years for analyses of the gait pattern while walking at the Gait Real-time Analysis Interactive Lab (GRAIL)…
- Trial name
- NCT06400043
- Testing
- Cognitive dual-task, Motor dual-task
- Where
- 2 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- University Ghent
Autism Spectrum Disorder
Improving Autistic Children's Experiences of Dental Care With Class-integrated Social Story
Children with autism spectrum disorder (ASD) are more likely to have unmet dental needs. Due to hypersensitivity and oral defensiveness, new or unexpected stimuli during dental examinations often precipitate anxiety and stress.
- Trial name
- NCT07166978
- Testing
- Social story
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- The University of Hong Kong
Cardiovascular Diseases
Wearable Ultrasound for Cardiac Monitoring During Surgery and in Intensive Care
This study aims to evaluate the accuracy, feasibility, and clinical usefulness of a wearable ultrasound imaging system for cardiac monitoring during perioperative care and in intensive care units (ICUs).
- Trial name
- NCT07891052
- Testing
- Wearable Ultrasound Imaging System
- Volunteers
- 600 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke, Alzheimer s Disease
Development, Validation and Normative Data of the Italian Battery for the Recognition of Famous Faces (FAME)
The I-FACE project aims to develop and validate a battery to assess famous-face recognition in people with neurodegenerative diseases and stroke.
- Conditions
- Stroke, Alzheimer s Disease, Frontotemporal Degeneration (FTD)
- Trial name
- I-FACE (NCT07911878)
- Testing
- Neuropsychological assessment using the I-FACE battery
- Where
- 10 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Creation of an Italian Network of Biobanks of Rare Diseases
ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria
Rare diseases (RDs) have been defined by the European Union (EU) as life-threatening or chronically debilitating conditions affecting less than 1 person in 2000.
- Trial name
- SATELLITES (NCT06782230)
- Where
- Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Complementary Feeding, Pediatric Nurse
The Effect of Technology-Based Education Given to Mothers During the Transition to Complementary Feeding on Infant Development, Transition to Complementary Feeding Behavior, and Mothers' Anxiety Levels
This study will be conducted as a randomized controlled pre-test post-test study to determine the effects of technology-based complementary feeding training given to mothers during the transition period of babies to complementary…
- Trial name
- NCT07487493
- Testing
- Transition to traditional complementary feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Physical Activity, Intellectual Disabilities
Advancing Cardiovascular Health Among Adolescents With Intellectual Disabilities: Co-Development of Technology Interventions to Enhance Physical Activity
Adolescents with intellectual disabilities (ID) face significant health issues, particularly in managing chronic conditions such as cardiovascular (CV) health risks.
- Conditions
- Physical Activity, Intellectual Disabilities, Cardiovascular Health
- Trial name
- NCT07919171
- Testing
- Virtual reality physical activity health promotion intervention
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Michigan State University
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